Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Andrew L. Wood"'
Autor:
Daniel J. Bolland, Hashem Koohy, Andrew L. Wood, Louise S. Matheson, Felix Krueger, Michael J.T. Stubbington, Amanda Baizan-Edge, Peter Chovanec, Bryony A. Stubbs, Kristina Tabbada, Simon R. Andrews, Mikhail Spivakov, Anne E. Corcoran
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2475-2487 (2016)
Variable (V), diversity (D), and joining (J) (V(D)J) recombination is the first determinant of antigen receptor diversity. Understanding how recombination is regulated requires a comprehensive, unbiased readout of V gene usage. We have developed VDJ
Externí odkaz:
https://doaj.org/article/2754b12283b14484b5441338b9c3ac7a
The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF
Autor:
Andrew L. Wood, Anne E. Corcoran, Changfeng Chen, Colette Johnston, Marjorie A. Oettinger, John W. Morris, Yanqun Wang, Ruslan I. Sadreyev, Yuka Namiki, Adam G. W. Matthews, Katrina B. Morshead, David N. Ciccone
Publikováno v:
The Journal of Biological Chemistry
Antigen receptor assembly in lymphocytes involves stringently-regulated coordination of specific DNA rearrangement events across several large chromosomal domains. Previous studies indicate that transcription factors such as paired box 5 (PAX5), Yin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703980a728e369b78c42da1d818b641d
https://doi.org/10.1074/jbc.ra118.007348
https://doi.org/10.1074/jbc.ra118.007348
Autor:
Andrew L. Wood, Robert W. Lindeman, Sungchul Jung, Pramuditha L. Abhayawardhana, Simon Hoermann
Publikováno v:
VR
Supporting perceptual-cognitive tasks is an important part of our daily lives. We use rich, multi-sensory feedback through sight, sound, touch, smell, and taste to support better perceptual-cognitive things we do, such as sports, cooking, and searchi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3204ea9a611eb4b14de394c2c9534ceb
https://doi.org/10.1109/vr46266.2020.00067
https://doi.org/10.1109/vr46266.2020.00067
Autor:
Simon Andrews, Andrew L. Wood, Amanda Baizan-Edge, Hashem Koohy, Felix Krueger, Daniel J. Bolland, Mikhail Spivakov, Kristina Tabbada, Louise S. Matheson, Peter Chovanec, Anne E. Corcoran, Bryony A. Stubbs, Michael J. T. Stubbington
Publikováno v:
Cell Reports
Cell Reports, Vol 15, Iss 11, Pp 2475-2487 (2016)
Cell Reports, Vol 15, Iss 11, Pp 2475-2487 (2016)
Summary Variable (V), diversity (D), and joining (J) (V(D)J) recombination is the first determinant of antigen receptor diversity. Understanding how recombination is regulated requires a comprehensive, unbiased readout of V gene usage. We have develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bafc076a00f9ae1dd289efc37c33575
http://europepmc.org/articles/PMC4914699
http://europepmc.org/articles/PMC4914699
Autor:
Nick Young, Stephen Robjohns, Mark Reacher, David J Roberts, Andrew L. Wood, Sandra White, Ayoub Saei, Helen Smith, Vicky Massey, David Wilcox, Tony Fletcher, Ovnair Sepai, Neville Q. Verlander, Diane Edwards, John W. Morris, Gill Davies, Semina Makhani, Giovanni Leonardi
Publikováno v:
ISEE Conference Abstracts. 2018
The protective effect of community water fluoridation (CWF) on caries is established, but secular changes may modify its impact. Relationships with adverse health outcomes have also been alleged. W...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0976bbbd95c9a3677b468c9e23937e42
https://doi.org/10.1289/isesisee.2018.p02.3141
https://doi.org/10.1289/isesisee.2018.p02.3141
Autor:
Anne E. Corcoran, Andrew L. Wood, Louise S. Matheson, Daniel J. Bolland, Felix Krueger, Peter Chovanec, Simon Andrews
Publikováno v:
Nature protocols. 13(6)
VDJ-seq is a DNA-based, high-throughput sequencing method that uses biotinylated J gene primers and UMIs to quantify immunoglobulin diversity in an unbiased manner on a per-cell basis. For high-throughput sequencing and quantification of immunoglobul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173a3f834ac88d6e893e62da5e05bcc0
https://pubmed.ncbi.nlm.nih.gov/29725123
https://pubmed.ncbi.nlm.nih.gov/29725123
Publikováno v:
Journal of Biological Chemistry. 285:9327-9338
During immunoglobulin heavy chain (Igh) V(D)J recombination, D to J precedes V to DJ recombination in an ordered manner, controlled by differential chromatin accessibility of the V and DJ regions and essential for correct antibody assembly. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7504d5a4432e4ca07e72ed39d3b4ef1
https://doi.org/10.1074/jbc.m109.098251
https://doi.org/10.1074/jbc.m109.098251
Autor:
John Collinge, Jacqueline M. Linehan, Emmanuel A. Asante, Melanie Desbruslais, Jonathan D. F. Wadsworth, Andrew L. Wood, Susan Joiner, Julie Welch, Ian Gowland, Andrew F. Hill, Sarah E. Lloyd
Publikováno v:
The EMBO Journal. 21:6358-6366
Variant Creutzfeldt-Jakob disease (vCJD) has been recognized to date only in individuals homozygous for methionine at PRNP codon 129. Here we show that transgenic mice expressing human PrP methionine 129, inoculated with either bovine spongiform ence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1937ef8b5fccbe216345fc2e84eaa5fd
https://doi.org/10.1093/emboj/cdf653
https://doi.org/10.1093/emboj/cdf653
Publikováno v:
Advances in experimental medicine and biology. 650
V(D)J recombination in lymphocytes is the cutting and pasting together of antigen receptor genes in cis to generate the enormous variety of coding sequences required to produce diverse antigen receptor proteins. It is the key role of the adaptive imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bd69d722772204e9b1bb6dd09bd1b3d
https://pubmed.ncbi.nlm.nih.gov/19731801
https://pubmed.ncbi.nlm.nih.gov/19731801
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781441902955
V(D)J recombination in lymphocytes is the cutting and pasting together of antigen receptor genes in cis to generate the enormous variety of coding sequences required to produce diverse antigen receptor proteins. It is the key role of the adaptive imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ccd6f7190c91a61b21dae292de00b96
https://doi.org/10.1007/978-1-4419-0296-2_5
https://doi.org/10.1007/978-1-4419-0296-2_5
