Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrew L. Staley"'
Autor:
Suzanne Chamberland, May D. Lee, Hans Fuernkranz, Olga Lomovskaya, Andrew L. Staley, Julie C. Lee, Mark S. Warren, George H. Miller, Jorge L. Galazzo
Publikováno v:
Il Farmaco. 56:81-85
A library of 85000 microbial fermentation extracts was screened for inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa and Candida albicans. New compounds EA-371alpha and EA-371delta were isolated and demonstrated to be potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5743e78baa7884932c32a8d8ed8eae1b
https://doi.org/10.1016/s0014-827x(01)01002-3
https://doi.org/10.1016/s0014-827x(01)01002-3
Publikováno v:
The Journal of Organic Chemistry. 60:2786-2791
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9469d8474dde3fdc15902e425f51e26
https://doi.org/10.1021/jo00114a029
https://doi.org/10.1021/jo00114a029
Autor:
Kenneth L. Rinehart, Andrew L. Staley
Publikováno v:
ChemInform. 26
Three new tetrahydroanthracene antibiotics have been isolated from modified culture broths of Streptomyces spectabilis. The new compounds, spectomycins Al, A2 and Bl, exist as monomeric (C20H20O7, Al; C19H18O7, A2) and as symmetrical dimeric (C38H34O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::029753a9bd2d3a16f5f6b88d4520e2f1
https://doi.org/10.1002/chin.199523254
https://doi.org/10.1002/chin.199523254
Autor:
May D. Lee, Hans Fuernkranz, Andrew L. Staley, Julie C. Lee, George H. Miller, Olga Lomovskaya, Mark S. Warren, Suzanne Chamberland, Jorge L. Galazzo
Publikováno v:
ChemInform. 32
A library of 85000 microbial fermentation extracts was screened for inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa and Candida albicans. New compounds EA-371alpha and EA-371delta were isolated and demonstrated to be potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9da0949958141c28e442740d78403c79
https://doi.org/10.1002/chin.200128235
https://doi.org/10.1002/chin.200128235
Publikováno v:
Proceedings of the National Academy of Sciences. 88:1878-1882
The Gram-negative bacterium Pseudomonas aeruginosa produces the phenolic siderophore pyochelin. Salicylic acid is an intermediate in the pyochelin biosynthetic pathway, and mutants blocked in salicylic acid biosynthesis (Sal-) are able to incorporate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5faf38df15e2cec7b13d3d867f6bab
https://doi.org/10.1073/pnas.88.5.1878
https://doi.org/10.1073/pnas.88.5.1878
Autor:
Kenneth L. Rinehart, Andrew L. Staley
Publikováno v:
The Journal of antibiotics. 47(12)
Three new tetrahydroanthracene antibiotics have been isolated from modified culture broths of Streptomyces spectabilis. The new compounds, spectomycins Al, A2 and Bl, exist as monomeric (C20H20O7, Al; C19H18O7, A2) and as symmetrical dimeric (C38H34O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3f7478e8e1a46e0fdb61c6c788f056
https://pubmed.ncbi.nlm.nih.gov/7844036
https://pubmed.ncbi.nlm.nih.gov/7844036
Autor:
Jon Clardy, Andrew L. Staley
Publikováno v:
Anticancer Drug Discovery and Development: Natural Products and New Molecular Models ISBN: 9781461361183
As part of the NCI’s broader goal of finding new leads to therapeutic agents in cancer chemotherapy, our National Cooperative Natural Product Drug Discovery Group (NCNPDDG) was organized to access a relatively understudied source of natural product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e371ec26efa025111dc835c999f75be
https://doi.org/10.1007/978-1-4615-2610-0_3
https://doi.org/10.1007/978-1-4615-2610-0_3
Publikováno v:
Secondary-Metabolite Biosynthesis and Metabolism ISBN: 9781461363125
Study of the bioconversion of primary metabolites to antibiotics can provide a diverse array of novel information. The usual approach is to determine the pathway of carbon during the bioconversion and propose intermediates for further study. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe83d8fc19552b3a3ef8bab360c50ae
https://doi.org/10.1007/978-1-4615-3012-1_4
https://doi.org/10.1007/978-1-4615-3012-1_4
Autor:
Kenneth L. Rinehart, Andrew L. Staley
Publikováno v:
The Journal of antibiotics. 44(2)
[Carboxy-]sp14C]-3-amino-5-hydroxybenzoic acid (AHBA) has been shown to be incorporated by Streptomyces spectabilis to the extent of greater than 0.1% (35:1 dilution) in the ansamycin antibiotic streptovaricin C, the major component of the streptovar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa40754c5ee2f02811b7fbda9091ace
https://pubmed.ncbi.nlm.nih.gov/1672686
https://pubmed.ncbi.nlm.nih.gov/1672686