Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Andrew L. Salzman"'
Autor:
Tuvshintugs Baljinnyam, Yosuke Niimi, John R. Salsbury, Satoshi Fukuda, Casey M. Ouellette, Clark R. Andersen, Yasutaka Hirasawa, Donald A. Prough, C. Edwin Garner, Andrew L. Salzman, Perenlei Enkhbaatar
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Characterization of the pathophysiology of ARDS following chlorine gas inhalation in clinically relevant translational large animal models is essential, as the opportunity for clinical trials in this type of trauma is extremely limited. To i
Externí odkaz:
https://doaj.org/article/92f5f5112ba446bf8f9d92c0a9c0e0f1
Autor:
Satoshi Fukuda, Yosuke Niimi, Yasutaka Hirasawa, Ennert R. Manyeza, C. Edwin Garner, Garry Southan, Andrew L. Salzman, Donald S. Prough, Perenlei Enkhbaatar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In sepsis, microvascular hyperpermeability caused by oxidative/nitrosative stress (O&NS) plays an important role in tissue edema leading to multi-organ dysfunctions and increased mortality. We hypothesized that a novel compound R-107, a modu
Externí odkaz:
https://doaj.org/article/0a205f198d544ea58822c974d20c9099
Autor:
Hiroshi Ito, Erik Malgerud, Sven Asmussen, Ernesto Lopez, Andrew L. Salzman, Perenlei Enkhbaatar
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-8 (2017)
Abstract Background Septic shock is a major cause of death in intensive care units around the world . The aim of the study was to investigate whether the novel drug R-100 (a superoxide degradation catalyst and nitric oxide donor) improves pulmonary f
Externí odkaz:
https://doaj.org/article/a0d07bf8b5824090899913fafb2449ee
Autor:
José A. Guevara-Patiño, I. Caroline Le Poole, Manuel F. Fernandez, Richard Duff, Andrew L. Salzman, Steven W. Henning, James P. Mahon, Alfred Rademaker, Farshid Azarafrooz
Publikováno v:
Journal of Investigative Dermatology. 138:2531-2539
Human HSP70iQ435A carries a single amino-acid modification within the dendritic cell activating region and tolerizes dendritic cells in vitro. The underlying DNA was used to prevent and treat disease in vitiligo mouse models through reduced dendritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f06fc7d5a66145a85838a74bb04c7c84
https://doi.org/10.1016/j.jid.2018.06.186
https://doi.org/10.1016/j.jid.2018.06.186
Autor:
Nicola J. Curtin, Nathan A. Berger, Solomon H. Snyder, Raymond A. Swanson, Peter Radermacher, Csaba Szabó, Pal Pacher, Francisco Garcia Soriano, Robert S. B. Clark, Robert P. Strosznajder, Flavio Moroni, A. Hamid Boulares, Balazs Sumegi, Andrew L. Salzman, Valina L. Dawson, Salvatore Cuzzocrea, Alberto Chiarugi, Ted M. Dawson, Alexander Bürkle, Lucas Liaudet, György Haskó, Valérie C. Besson
Publikováno v:
British Journal of Pharmacology. 175:192-222
The recent clinical availability of the PARP inhibitor olaparib (Lynparza) opens the door for potential therapeutic repurposing for non-oncological indications. Considering (a) the preclinical efficacy data with PARP inhibitors in non-oncological dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef6a56426ace2dc158875362d94a3819
https://doi.org/10.1111/bph.13748
https://doi.org/10.1111/bph.13748
Autor:
Hiroshi Ito, Perenlei Enkhbaatar, Erik Malgerud, Ernesto Lopez, Sven Asmussen, Andrew L. Salzman
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-8 (2017)
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-8 (2017)
Background Septic shock is a major cause of death in intensive care units around the world . The aim of the study was to investigate whether the novel drug R-100 (a superoxide degradation catalyst and nitric oxide donor) improves pulmonary function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566076a92fb2ac6c85d83bbfdfcaa324
https://pubmed.ncbi.nlm.nih.gov/29282084
https://pubmed.ncbi.nlm.nih.gov/29282084
Autor:
Lillian D. Traber, Andrew L. Salzman, David N. Herndon, Dirk M. Maybauer, Martin Westphal, Csaba Szabó, Daniel L. Traber, Marc O. Maybauer
Publikováno v:
Burns. 37:842-850
This prospective, randomized, controlled experimental study examined the effects of the peroxynitrite decomposition catalyst WW-85 on global hemodynamics and regional microvascular blood flow (RMBF) in an established ovine model of septic shock follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df915078597769a847502015da2618d9
https://doi.org/10.1016/j.burns.2010.12.020
https://doi.org/10.1016/j.burns.2010.12.020
Autor:
Hal K. Hawkins, Martin Westphal, Robert A. Cox, Andrew L. Salzman, David N. Herndon, Lillian D. Traber, Eszter M. Horváth, Dirk M. Maybauer, Marc O. Maybauer, Garry J. Southan, Daniel L. Traber, Csaba Szabó, Levente Kiss
Publikováno v:
Shock. 35:148-155
Systemic inflammatory response syndrome is associated with excessive production of nitric oxide (NO·) and superoxide (O2), forming peroxynitrite, which in turn, acts as a terminal mediator of cellular injury by producing cell necrosis and apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b713768c402c760578f36fd28768b88
https://doi.org/10.1097/shk.0b013e3181eb4556
https://doi.org/10.1097/shk.0b013e3181eb4556
Autor:
Garry J. Southan, Salsbury Randy, Koji Ihara, Donald S. Prough, Yasutaka Hirasawa, Yosuke Niimi, Perenlei Enkhbaatar, Satoshi Fukuda, Andrew L. Salzman, Robert H. Cox, Edwin Garner
Publikováno v:
Critical Care Medicine. 46:519-519
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d2ce12882a15469b31f913d21d63a3c
https://doi.org/10.1097/01.ccm.0000529077.21387.bb
https://doi.org/10.1097/01.ccm.0000529077.21387.bb