Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrew L. Rozelle"'
Autor:
Leonardo Punzi, David M. Lee, Tamsin M. Lindstrom, Heidi H. Wong, Carla R. Scanzello, Gurkan Bebek, Christin M. Lepus, Mary K. Crow, V. Michael Holers, Tony Wyss-Coray, James F. Crish, Jason J. Song, Inyong Hwang, Susan Y. Ritter, Angelo Encarnacion, Steven R. Goldring, Joshua M. Thurman, Stuart B. Goodman, William H. Robinson, Andrew L. Rozelle, Reuben Gobezie, Mehrdad Shamloo, Nirmal K. Banda, D Meegan Larsen, Qian Wang
Publikováno v:
Nature Medicine. 17:1674-1679
Osteoarthritis, characterized by the breakdown of articular cartilage in synovial joints, has long been viewed as the result of 'wear and tear'. Although low-grade inflammation is detected in osteoarthritis, its role is unclear. Here we identify a ce
Publikováno v:
JCR: Journal of Clinical Rheumatology. 14:285-288
Malignancy and interstitial lung disease (ILD) are 2 conditions associated with dermatomyositis (DM) that are responsible for a significant portion of the morbidity and mortality related to this disease; however, they rarely occur in the same patient
Publikováno v:
The Journal of Cell Biology
ADP-ribosylation factor (Arf) 6 regulates the movement of membrane between the plasma membrane (PM) and a nonclathrin-derived endosomal compartment and activates phosphatidylinositol 4-phosphate 5-kinase (PIP 5-kinase), an enzyme that generates phosp
Autor:
Katherine Luby-Phelps, Gerard Marriott, Robert H. Insall, Mariëtte H.E. Driessens, Masaya Yamamoto, Alan Hall, Andrew L. Rozelle, Helen L. Yin, Michael G. Roth, Laura M. Machesky
Publikováno v:
Current Biology. 10(6):311-320
Background: Phosphatidylinositol 4,5-bisphosphate (PIP2) has been implicated in the regulation of the actin cytoskeleton and vesicle trafficking. It stimulates de novo actin polymerization by activating the pathway involving the Wiskott-Aldrich syndr
Autor:
Andrew L. Rozelle, William H. Robinson, Christine Austin, Philip Doble, Rudolf Grimm, Dominic J. Hare
Publikováno v:
Metallomics : integrated biometal science. 1(2)
Laser ablation inductively coupled plasma mass spectrometry (LA ICP-MS) was employed to image deposits of calcium phosphate based crystals in knee cartilage and synovial fluid from arthritic patients. A reaction/collision cell containing hydrogen min
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 171(5)
The localization of receptors, signaling intermediates, and cytoskeletal components at the T cell/APC interface is thought to be a major determinant of efficient T cell activation. However, important questions remain open. What are the dynamics of th
Autor:
Xiaodong Wang, Hui Qiao Sun, Marisan Mejillano, Helen L. Yin, Andrew L. Rozelle, Masaya Yamamoto
Publikováno v:
The Journal of biological chemistry. 276(3)
Phosphoinositides such as phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate promote cell survival and protect against apoptosis by activating Akt/PKB, which phosphorylates components of the apoptotic machinery. We now