Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Andrew L. Lewis and"'
Autor:
Ayele H. Negussie, Andrew S. Mikhail, Joshua W. Owen, Natalie Hong, Camella J. Carlson, Yiqing Tang, Kendal Paige Carrow, Michal Mauda-Havakuk, Andrew L. Lewis, John W. Karanian, William F. Pritchard, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hepatocellular carcinoma (HCC) is an aggressive liver cancer with limited effective treatment options. In this study, we selected TLR agonists imiquimod (IMQ), gardiquimod (GARD), GS-9620 and DSR 6434, and a small molecule checkpoint inhibit
Externí odkaz:
https://doaj.org/article/a5f7912257d54f5cb2ffe67f7c41928a
Autor:
Ayele H. Negussie, Andrew S. Mikhail, Joshua W. Owen, Natalie Hong, Camella J. Carlson, Yiqing Tang, Kendal Paige Carrow, Michal Mauda-Havakuk, Andrew L. Lewis, John W. Karanian, William F. Pritchard, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/21cccb8cdbf44c99b3ea9c43414d7873
Autor:
Ayele H. Negussie, Quirina M. B. de Ruiter, Hugh Britton, Danielle R. Donahue, Quentin Boffi, Young-Seung Kim, William F. Pritchard, Chrit Moonen, Gert Storm, Andrew L. Lewis, Bradford J. Wood
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Current therapy for hypervascular cancers, e.g., hepatocellular carcinoma, includes occlusion of the tumor blood supply by arterial infusion of embolic microspheres (beads) suspended in iodine-based contrast under fluoroscopic guidance. Avai
Externí odkaz:
https://doaj.org/article/5c8343e6e7924265820253b48addecee
Autor:
Alireza Meghdadi, Stephen A. Jones, Venisha A. Patel, Andrew L. Lewis, Timothy M. Millar, Dario Carugo
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1725 (2022)
Sclerotherapy is among the least invasive and most commonly utilised treatment options for varicose veins. Nonetheless, it does not cure varicosities permanently and recurrence rates are of up to 64%. Although sclerosing foams have been extensively c
Externí odkaz:
https://doaj.org/article/2b5aff9a99024fb48ee5e481ff053647
Autor:
Elisabetta Bottaro, Jemma Paterson, Xunli Zhang, Martyn Hill, Venisha A. Patel, Stephen A. Jones, Andrew L. Lewis, Timothy M. Millar, Dario Carugo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Foam sclerotherapy is clinically employed to treat varicose veins. It involves intravenous injection of foamed surfactant agents causing endothelial wall damage and vessel shrinkage, leading to subsequent neovascularization. Foam production methods u
Externí odkaz:
https://doaj.org/article/758cf565ed0c42cfa102e13076de1433
Autor:
Richard G. Pearson, Tahir Masud, Elaine Blackshaw, Andrew Naylor, Michael Hinchcliffe, Kirk Jeffery, Faron Jordan, Anjumn Shabir-Ahmed, Gareth King, Andrew L. Lewis, Lisbeth Illum, Alan C. Perkins
Publikováno v:
Pharmaceutics, Vol 11, Iss 6, p 265 (2019)
Nasal delivery of large peptides such as parathyroid 1-34 (PTH 1-34) can benefit from a permeation enhancer to promote absorption across the nasal mucosa into the bloodstream. Previously, we have published an encouraging bioavailability (78%), relati
Externí odkaz:
https://doaj.org/article/835f2d5b3a3e42739c1270f537c2dac0
Autor:
Andrew S. Mikhail, William F. Pritchard, Ayele H. Negussie, Gazi Inkiyad, Dilara J. Long, Michal Mauda-Havakuk, Paul G. Wakim, William van der Sterren, Elliot B. Levy, Andrew L. Lewis, John W. Karanian, Bradford J. Wood
Publikováno v:
Investigative radiology. 57(8)
The aims of this study were to develop a model to estimate drug dose delivered to tumors after transarterial chemoembolization (TACE) with radiopaque drug-eluting beads (DEBs) based on DEB density on cone-beam computed tomography (CT) and to evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e2c650fe90e4325772a1c709213535
https://pubmed.ncbi.nlm.nih.gov/35239613
https://pubmed.ncbi.nlm.nih.gov/35239613
Autor:
Elizabeth J. Wright, Nigel W. Hodson, Michael J. Sherratt, Moustapha Kassem, Andrew L. Lewis, Christine Wallrapp, Nadim Malik, Cathy M. Holt
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Background. Mesenchymal stem cells (MSCs) and glucagon-like peptide-1 (GLP-1) are being tested as treatment strategies for myocardial infarction (MI); however, their mechanisms in the heart are not fully understood. Methods. We examined the effects o
Externí odkaz:
https://doaj.org/article/5a3d799a70b649eebeb6f93fa7285d6e
Publikováno v:
Biomedical Glasses, Vol 6, Iss 1, Pp 34-49 (2020)
This study investigates the role of yttrium in phosphate-based glasses in the system 45(P2O5)–25(CaO)– (30-x)(Na2O)–x(Y2O3) (0≤x≤5) prepared via melt quenching and focuses on their structural characterisation and degradation properties. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dd5bfad81b6786a895833a1aca1a0e
https://doaj.org/article/7ea63f8e8209443981a64e53725a9004
https://doaj.org/article/7ea63f8e8209443981a64e53725a9004
Autor:
Alireza Meghdadi, Andrew L. Lewis, Stephen A. Jones, Venisha A. Patel, Timothy M. Millar, Dario Carugo
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 109:69-91
Varicose veins are chronic venous defects that affect >20% of the population in developed countries. Among potential treatments, sclerotherapy is one of the most commonly used. It involves endovenous injection of a surfactant solution (or foam) in va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51ac38dca30d83fb7fca6ec14dbbccf
https://doi.org/10.1002/jbm.b.34681
https://doi.org/10.1002/jbm.b.34681