Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew L. Garfoot"'
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background The protozoan pathogen Toxoplasma gondii has the unique ability to develop a chronic infection in the brain of its host by transitioning from the fast growing tachyzoite morphology to latent bradyzoite morphology. A hallmark of th
Externí odkaz:
https://doaj.org/article/a8fcafae12c642c4b1727882e20d1656
Autor:
Andrew L. Garfoot, Kristie D. Goughenour, Marcel Wüthrich, Murugesan V. S. Rajaram, Larry S. Schlesinger, Bruce S. Klein, Chad A. Rappleye
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia i
Externí odkaz:
https://doaj.org/article/5c09d23e88e94f35870097fd644ba235
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT The fungal pathogen Histoplasma capsulatum parasitizes host phagocytes. To avoid antimicrobial immune responses, Histoplasma yeasts must minimize their detection by host receptors while simultaneously interacting with the phagocyte. Pathogen
Externí odkaz:
https://doaj.org/article/9cb783cc7c744ebe9e2b7d87095c074a
Autor:
Gina M. Gallego-Lopez, Carolina Mendoza Cavazos, Andrés M. Tibabuzo Perdomo, Andrew L. Garfoot, Roberta M. O’Connor, Laura J. Knoll
Publikováno v:
Infection and immunity. 90(2)
Animals with a chronic infection of the parasite Toxoplasma gondii are protected against lethal secondary infection with other pathogens. Our group previously determined that soluble T. gondii antigens (STAg) can mimic this protection and be used as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6dc8e2f8a150027e5d50b855f70bc8
https://pubmed.ncbi.nlm.nih.gov/34928716
https://pubmed.ncbi.nlm.nih.gov/34928716
Autor:
Andrew L. Garfoot, Gina M Gallego-Lopez, Roberta M. O'Connor, Andrés M. Tibabuzo Perdomo, Laura J. Knoll, Carolina Mendoza Cavazos
Background: Protective immune responses to Cryptosporidium parvum, a zoonotic, gastrointestinal parasite, are primarily dependent on the presence of interferon-gamma (IFNγ). We discovered that treatment with soluble T. gondii antigen (STAg) reduces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43173403bc7b638a6bbff7ed47cc00d3
https://doi.org/10.21203/rs.3.rs-491899/v1
https://doi.org/10.21203/rs.3.rs-491899/v1
Autor:
Chad A. Rappleye, Andrew L. Garfoot
Publikováno v:
FEBS Journal. 283:619-633
The fungal pathogen Histoplasma capsulatum causes respiratory and disseminated disease, even in immunocompetent hosts. In contrast to opportunistic pathogens, which are readily controlled by phagocytic cells, H. capsulatum yeasts are able to infect m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0f3387d40ff484dc47c516869cd8f6
https://doi.org/10.1111/febs.13389
https://doi.org/10.1111/febs.13389
Autor:
Andrew L, Garfoot, Kacey L, Dearing, Andrew D, VanSchoiack, Vicki H, Wysocki, Chad A, Rappleye
Publikováno v:
The Journal of biological chemistry. 292(12)
Fungal cell walls contain β-glucan polysaccharides that stimulate immune responses when recognized by host immune cells. The fungal pathogen Histoplasma capsulatum minimizes detection of β-glucan by host cells through at least two mechanisms: conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cffcf5b2ee93c4bdbbb9cc78758a7008
https://pubmed.ncbi.nlm.nih.gov/28154008
https://pubmed.ncbi.nlm.nih.gov/28154008
Autor:
Christine M. Toutain-Kidd, Joseph S. Lam, Daniel J. Wozniak, John H. Hammond, Andrew L. Garfoot, Michael E. Zegans, Edward F. Griffin
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:4112-4122
Polysorbate 80 (PS80) is a nonionic surfactant and detergent that inhibits biofilm formation by Pseudomonas aeruginosa at concentrations as low as 0.001% and is well tolerated in human tissues. However, certain clinical and laboratory strains (PAO1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d7942e68471dda4d621e2c066484c6
https://doi.org/10.1128/aac.00373-12
https://doi.org/10.1128/aac.00373-12
During infection of the mammalian host, Histoplasma capsulatum yeasts survive and reside within macrophages of the immune system. Whereas some intracellular pathogens escape into the host cytosol, Histoplasma yeasts remain within the macrophage phago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ba45d9b8c41d3099199b314ef6f504
https://europepmc.org/articles/PMC3911860/
https://europepmc.org/articles/PMC3911860/
Publikováno v:
Biology of Reproduction. 85:6-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945e16fa34587e4e9ae02a64605e4907
https://doi.org/10.1093/biolreprod/85.s1.6
https://doi.org/10.1093/biolreprod/85.s1.6