Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrew L'Huillier"'
Autor:
Michael F. Princiotta, Robert G. Petit, Brandon D. Coder, Elena V. Filippova, Cristina Mottershead, Susan Armington, Andrew L'Huillier, Daniel O. Villarreal
Expression of Lm-AH1 vaccine construct.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8d979c4faff608e88b8d2c69c5a249
https://doi.org/10.1158/0008-5472.22420151
https://doi.org/10.1158/0008-5472.22420151
Autor:
Michael F. Princiotta, Robert G. Petit, Brandon D. Coder, Elena V. Filippova, Cristina Mottershead, Susan Armington, Andrew L'Huillier, Daniel O. Villarreal
CCR8 mAb treatment mediates potent antitumor activity, suppressing MC38 tumor growth and improving long-term survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f0c55012fe05fc657a37ced5d44bb7
https://doi.org/10.1158/0008-5472.22420157
https://doi.org/10.1158/0008-5472.22420157
Autor:
Michael F. Princiotta, Robert G. Petit, Brandon D. Coder, Elena V. Filippova, Cristina Mottershead, Susan Armington, Andrew L'Huillier, Daniel O. Villarreal
File contains the supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae3fbb5a8a4e8f4c3308394c875da74
https://doi.org/10.1158/0008-5472.22420148.v1
https://doi.org/10.1158/0008-5472.22420148.v1
Autor:
Michael F. Princiotta, Robert G. Petit, Brandon D. Coder, Elena V. Filippova, Cristina Mottershead, Susan Armington, Andrew L'Huillier, Daniel O. Villarreal
CCR8 is a chemokine receptor expressed principally on regulatory T cells (Treg) and is known to be critical for CCR8+ Treg-mediated immunosuppression. Recent studies have demonstrated that CCR8 is uniquely upregulated in human tumor-resident Tregs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e66077d316cfdd8c6d856f599950bd
https://doi.org/10.1158/0008-5472.c.6510569.v1
https://doi.org/10.1158/0008-5472.c.6510569.v1
Autor:
Michael F. Princiotta, Robert G. Petit, Brandon D. Coder, Elena V. Filippova, Cristina Mottershead, Susan Armington, Andrew L'Huillier, Daniel O. Villarreal
The frequency of peripheral Tregs in tumor-bearing αCCR8-treated mice and the effects of αCCR8 on ex vivo tumor CD8+ and CD4+ T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227cf679b41f4436ca7ff0b231365e26
https://doi.org/10.1158/0008-5472.22420154
https://doi.org/10.1158/0008-5472.22420154
Autor:
Robert Petit, Michael F. Princiotta, Elena Filippova, Susan Armington, Cristina Mottershead, Daniel O. Villarreal, Andrew L'Huillier, Brandon Coder
Publikováno v:
Cancer Research. 78:5340-5348
CCR8 is a chemokine receptor expressed principally on regulatory T cells (Treg) and is known to be critical for CCR8+ Treg-mediated immunosuppression. Recent studies have demonstrated that CCR8 is uniquely upregulated in human tumor-resident Tregs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e16c04d1fd27e63b473f410fd7b5486
https://doi.org/10.1158/0008-5472.can-18-1119
https://doi.org/10.1158/0008-5472.can-18-1119
Autor:
Elena Filippova, Kim Ramos, Susan Armington, Daniel O. Villarreal, Nithya Thambi, Michael F. Princiotta, Andrew L'Huillier, Cristina Mottershead, David Balli, Brandon Coder, Robert Petit
Publikováno v:
Cancer Research. 78:LB-149
Introduction: Virtually all tumors contain somatic mutations that can result in novel antigenic sequences that may be targeted by the host cellular immune response. Some of these mutations occur in preferential regions of specific genes commonly refe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aac5fa08e2308be0d58838965068162
https://doi.org/10.1158/1538-7445.am2018-lb-149
https://doi.org/10.1158/1538-7445.am2018-lb-149
Autor:
Andrew L'Huillier, Dipti Kelkar, Daniel O. Villarreal, Kim Ramos, David Balli, Cristina Mottershead, Elena Filippova, Hyewon Phee, James A. Johnston, Xiaoming Ju, Michael F. Princiotta, Brandon Coder, Robert Petit, Susan Armington
Publikováno v:
Cancer Research. 78:LB-148
Introduction: Neoantigens derived from tumor-specific mutations have been shown to drive tumor specific CD8+ T cell responses leading to tumor regression and extending overall survival. Frameshift mutations are estimated to generate up to nine times
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc2325bcc98191479538f35d7d86189
https://doi.org/10.1158/1538-7445.am2018-lb-148
https://doi.org/10.1158/1538-7445.am2018-lb-148
Autor:
Andrew L'Huillier, Arthur I. Roberts, Weifang Ling, Changshun Shao, Liying Zhang, Jimin Zhang, Xin Zhao, Anh D. Le, Yufang Shi, Songtao Shi, Guangwen Ren
Publikováno v:
The Journal of Immunology. 184:2321-2328
Cell–cell adhesion mediated by ICAM-1 and VCAM-1 is critical for T cell activation and leukocyte recruitment to the inflammation site and, therefore, plays an important role in evoking effective immune responses. However, we found that ICAM-1 and V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d19c463c1585c48936d8f78f384ef11
https://doi.org/10.4049/jimmunol.0902023
https://doi.org/10.4049/jimmunol.0902023
Publikováno v:
Cellular & Molecular Immunology. 9:369-370
The immune system can robustly respond to pathogens, while it is capable of maintaining tolerance to self and innocuous antigens, so that the body is not jeopardized by autoimmune reactivity. Under certain circumstances, nonetheless, control of homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df09f4c58533e628f0868128594d9150
https://doi.org/10.1038/cmi.2012.25
https://doi.org/10.1038/cmi.2012.25