Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Andrew Kyle"'
Autor:
Maura Greiser, Mariusz Karbowski, Aaron David Kaplan, Andrew Kyle Coleman, Nicolas Verhoeven, Carmen A Mannella, W Jonathan Lederer, Liron Boyman
Publikováno v:
eLife, Vol 12 (2023)
Mitochondrial ATP production in ventricular cardiomyocytes must be continually adjusted to rapidly replenish the ATP consumed by the working heart. Two systems are known to be critical in this regulation: mitochondrial matrix Ca2+ ([Ca2+]m) and blood
Externí odkaz:
https://doaj.org/article/165b4639279f459893cd06a93cbac943
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Abstract Objectives: Consenting donors for remnant clinical biospecimen donation is critical for scaling research biorepositories. Opt-in, low-cost, self-consenting for donations that solely relied on clinical staff and printed materials was recentl
Externí odkaz:
https://doaj.org/article/ce6d773c746249a9837c31c2ecfe0c49
Autor:
Marta Poblocka, Akang Leonard Bassey, Victoria M. Smith, Marta Falcicchio, Ana Sousa Manso, Mohammad Althubiti, XiaoBo Sheng, Andrew Kyle, Ruth Barber, Mark Frigerio, Salvador Macip
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract A wide range of diseases have been shown to be influenced by the accumulation of senescent cells, from fibrosis to diabetes, cancer, Alzheimer’s and other age-related pathologies. Consistent with this, clearance of senescent cells can prol
Externí odkaz:
https://doaj.org/article/0025965e081a437187edf55f3e63aa33
Autor:
Nick Evans, Ruslan Grygorash, Paul Williams, Andrew Kyle, Terrence Kantner, Ravindra Pathak, XiaoBo Sheng, Fabio Simoes, Hiteshri Makwana, Ricardo Resende, Elena de Juan, Alan Jenkins, David Morris, Aurelie Michelet, Frances Jewitt, Felicity Rudge, Nicolas Camper, Anaïs Manin, William McDowell, Martin Pabst, Antony Godwin, Mark Frigerio, Matthew Bird
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Antibody-drug conjugates (ADCs) have begun to fulfil their promise as targeted cancer therapeutics with ten clinical approvals to date. As the field matures, much attention has focused upon the key factors required to produce safe and efficacious ADC
Externí odkaz:
https://doaj.org/article/e322c470d7fb4d25b6de4ac481fa6602
Publikováno v:
Conference on Neural Information Processing Systems (NeurIPS), Dec 2024
Recent studies suggest that deep learning models inductive bias towards favoring simpler features may be one of the sources of shortcut learning. Yet, there has been limited focus on understanding the complexity of the myriad features that models lea
Externí odkaz:
http://arxiv.org/abs/2407.06076
Representation learning, and interpreting learned representations, are key areas of focus in machine learning and neuroscience. Both fields generally use representations as a means to understand or improve a system's computations. In this work, howev
Externí odkaz:
http://arxiv.org/abs/2405.05847
Autor:
Carvalho, Wilka, Saraiva, Andre, Filos, Angelos, Lampinen, Andrew Kyle, Matthey, Loic, Lewis, Richard L., Lee, Honglak, Singh, Satinder, Rezende, Danilo J., Zoran, Daniel
The Option Keyboard (OK) was recently proposed as a method for transferring behavioral knowledge across tasks. OK transfers knowledge by adaptively combining subsets of known behaviors using Successor Features (SFs) and Generalized Policy Improvement
Externí odkaz:
http://arxiv.org/abs/2310.15940
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 26-26 (2020)
OBJECTIVES/GOALS: BURRITO is an efficient strategy that provides full disclosure in the electronic medical record of a patient’s preference in real time. BURRITO uses printed materials only to inform patients and has a
Externí odkaz:
https://doaj.org/article/bf3bd13c67c74f60b52ff6ba572a6d0d
What can be learned about causality and experimentation from passive data? This question is salient given recent successes of passively-trained language models in interactive domains such as tool use. Passive learning is inherently limited. However,
Externí odkaz:
http://arxiv.org/abs/2305.16183
Autor:
Lampinen, Andrew Kyle
How should we compare the capabilities of language models (LMs) and humans? I draw inspiration from comparative psychology to highlight some challenges. In particular, I consider a case study: processing of recursively nested grammatical structures.
Externí odkaz:
http://arxiv.org/abs/2210.15303