Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Andrew Kolozsvary"'
Autor:
Stephen L. Brown, Andrew Kolozsvary, Derek M. Isrow, Karine Al Feghali, Karen Lapanowski, Kenneth A. Jenrow, Jae Ho Kim
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells and increases in toxicity when used in combination with radiation. In addition to various molecular and metabolic mechanisms that have been previously pro
Externí odkaz:
https://doaj.org/article/c7facccff35c4782aa3a1d340abd9356
Autor:
Jae Ho Kim, Karine A Al Feghali, Derek Isrow, Kenneth A. Jenrow, Karen Lapanowski, Andrew Kolozsvary, Stephen L. Brown
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology
Frontiers in Oncology
Introduction: Metformin, the most widely used treatment for diabetes, is lethal to cancer cells and increases in toxicity when used in combination with radiation. In addition to various molecular and metabolic mechanisms that have been previously pro
Publikováno v:
International Journal of Radiation Biology. 89:311-318
To summarize current knowledge regarding mechanisms of radiation-induced skin injury and medical countermeasures available to reduce its severity. Advances in radiation delivery using megavoltage and intensity modulated radiation therapy have permitt
Autor:
Andrew Kolozsvary, Jianguo Liu, Jae Ho Kim, Kenneth A. Jenrow, Stephen L. Brown, Karen Lapanowski
Publikováno v:
Journal of Neuro-Oncology. 101:449-456
Whole brain irradiation (WBI) is commonly administered therapeutically and is routinely associated with late delayed radiation injuries, manifesting as severe and irreversible cognitive impairment. Neural progenitors within the subgranular zone (SGZ)
Publikováno v:
Journal of Neuro-Oncology. 90:19-24
Viral vector mediated suicide gene therapy (SGT) involving thymidine kinase (TK) or cytosine deaminase (CD) have considerable promise in the treatment of malignant brain tumors. An unresolved issue is to what extent tumor hypoxia influences the outco
Publikováno v:
Journal of Neuro-Oncology. 82:119-124
Radiation-induced optic nerve damage was reduced by ramipril, a prodrug angiotensin-converting enzyme inhibitor (ACEI). This study was to determine the optimum dose and administration time of ramipril for mitigating radiation-induced optic neuropathy
Autor:
Stephen L. Brown, Hans Stricker, Xueqing Xia, Joseph D. Fenstermacher, Andrew Kolozsvary, Tavarekere N. Nagaraja, Guopei Zhu, Mei Lu, Svend O. Freytag, Gregory Heisey, Kenneth N. Barton, Jae Ho Kim, Hui Yan, Fang-Fang Yin
Publikováno v:
Molecular Therapy. 9(4):625-631
This study describes a quantitative method to measure the magnitude and distribution of gene expression following local delivery of an adenoviral vector containing the human sodium iodide symporter (hNIS) reporter gene into the canine prostate. Follo
Publikováno v:
Radiation Research. 157:500-505
Available imaging techniques have a limited ability to detect radiation-induced injury of the normal brain. In particular, there is no noninvasive method available for detection of structural or functional neuronal damage induced by radiation. This s
Publikováno v:
Radiation research. 182(3)
Radiation injury to skin poses substantial morbidity risks in the curative treatment of cancers and is also of concern in the context of radiological attack or nuclear accident scenarios. Late effects can be severe and are frequently characterized by
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 45:1035-1040
Purpose: Fractionated radiosurgery is being carried out in the clinic to improve the therapeutic ratio of single-dose radiosurgery using various fractionation schemes. Because there is a paucity of experimental radiobiological data in the literature