Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Andrew Kodani"'
Autor:
Kimino Fujimura, Amanda J. Guise, Tojo Nakayama, Christoph N. Schlaffner, Anais Meziani, Mukesh Kumar, Long Cheng, Dylan J. Vaughan, Andrew Kodani, Simon Van Haren, Kenneth Parker, Ofer Levy, Ann F. Durbin, Irene Bosch, Lee Gehrke, Hanno Steen, Ganeshwaran H. Mochida, Judith A. Steen
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106909- (2023)
Summary: Characterizing perturbation of molecular pathways in congenital Zika virus (ZIKV) infection is critical for improved therapeutic approaches. Leveraging integrative systems biology, proteomics, and RNA-seq, we analyzed embryonic brain tissues
Externí odkaz:
https://doaj.org/article/51cd38694972434695fcef207fb0e48f
Autor:
Andrew Kodani, Timothy W Yu, Jeffrey R Johnson, Divya Jayaraman, Tasha L Johnson, Lihadh Al-Gazali, Lāszló Sztriha, Jennifer N Partlow, Hanjun Kim, Alexis L Krup, Alexander Dammermann, Nevan J Krogan, Christopher A Walsh, Jeremy F Reiter
Publikováno v:
eLife, Vol 4 (2015)
Primary microcephaly (MCPH) associated proteins CDK5RAP2, CEP152, WDR62 and CEP63 colocalize at the centrosome. We found that they interact to promote centriole duplication and form a hierarchy in which each is required to localize another to the cen
Externí odkaz:
https://doaj.org/article/b40640f1f0e84ee9a3c58b1340bbe175
Autor:
Andrew Kodani, Kristeene A Knopp, Elizabeth Di Lullo, Hanna Retallack, Arnold R Kriegstein, Joseph L DeRisi, Jeremy F Reiter
Publikováno v:
EMBO Rep
Zika virus (ZIKV) is a flavivirus transmitted via mosquitoes and sex to cause congenital neurodevelopmental defects, including microcephaly. Inherited forms of microcephaly (MCPH) are associated with disrupted centrosome organization. Similarly, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714d04ef2a046616212959180b6af8ec
https://doi.org/10.15252/embr.202052211
https://doi.org/10.15252/embr.202052211
Autor:
Andrew J. Holland, Jeremy F. Reiter, Christopher A. Walsh, Allen Y. Chen, Andrew Kodani, Tyler C. Moyer
Publikováno v:
The Journal of Cell Biology
Kodani et al. identify a role for the mammalian homologue of yeast SFI1 as a regulator of centriole duplication. They show that SFI1 localizes USP9X to the centrosome to stabilize the microcephaly protein STIL to promote centriole duplication.
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76de6ad1503cfa7f09b4442f63b703d7
http://europepmc.org/articles/PMC6605807
http://europepmc.org/articles/PMC6605807
Autor:
Joseph L. DeRisi, Hanna Retallack, Jeremy F. Reiter, Andrew Kodani, Kristeene A. Knopp, Elizabeth Di Lullo, Arnold R. Kriegstein
Zika virus (ZIKV) is a flavivirus transmitted via mosquitoes and sex to cause congenital neurodevelopmental defects, including microcephaly. Inherited forms of microcephaly (MCPH) are associated with disrupted centrosome organization. Similarly, we f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a192ad3c559566e18bbed1fb90c78f7
https://doi.org/10.1101/2020.09.15.298083
https://doi.org/10.1101/2020.09.15.298083
Autor:
James Conner, Oliver D. King, Angela Lek, Monkol Lek, Lillian Mead, Kathryn R. Wagner, Keryn G. Woodman, Vincent T. Ho, Neville E. Sanjana, Justin B. Cohen, Shushu Huang, Louis M. Kunkel, Peter L. Jones, Anna Pakula, Yuanfan Zhang, Andrew Kodani, Alec M. DeSimone
Publikováno v:
Sci Transl Med
The emergence of CRISPR-Cas9 gene-editing technologies and genome-wide CRISPR-Cas9 libraries enables efficient unbiased genetic screening that can accelerate the process of therapeutic discovery for genetic disorders. Here, we demonstrate the utility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e95707ef4e2ef15d8ed9c5251b18b7b
https://europepmc.org/articles/PMC7304480/
https://europepmc.org/articles/PMC7304480/
Autor:
Alicia B. Byrne, Laura Isacco, R. Sean Hill, Wojciech Wiszniewski, Kristin W. Barañano, A. James Barkovich, Anne O’Donnell, David G. Vossler, Julie S. Cohen, Christopher A. Walsh, Kirsty McWalter, Edward Stronge, Christopher J. Yuskaitis, Andrew Kodani, Mustafa Sahin, Dilenny M. Gonzalez, Gabrielle M. Sejourne, Edward Yang, Pawel Gawlinski, Jennifer N. Partlow, S. Ali Fatemi, Abbe Lai, Connor J. Kenny
Publikováno v:
Neuron
Genes mutated in human neuronal migration disorders encode tubulin proteins and a variety of tubulin-binding and -regulating proteins, but it is very poorly understood how these proteins function together to coordinate migration. Additionally, the wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b762aa6ab6011c27bd4262d374ec7a9b
https://hdl.handle.net/11541.2/142192
https://hdl.handle.net/11541.2/142192
Autor:
Komal Patel, Xenophon Papademetris, Rebeca Borges-Monroy, Kiho Im, Xingshen Sun, Joseph B. Mandeville, Daniel Coman, Andrew Kodani, Fahmeed Hyder, Hojoong Kwak, Lawrence H. Staib, Dilenny M. Gonzalez, Ziying Yan, Richard S. Smith, Christopher A. Walsh, Steven C. Ryu, Kelly M. Girskis, Manavi Chatterjee, Peter P. Wang, Matthew B. Johnson, Yu Mi Woo, Byoung-Il Bae, P. Ellen Grant, Bo Liang, John F. Engelhardt
Publikováno v:
Nature
The human cerebral cortex is distinguished by its large size and abundant gyrification, or folding. However, the evolutionary mechanisms that drive cortical size and structure are unknown. Although genes that are essential for cortical developmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0ff5bcde28051085b3b147200b1b22
https://doi.org/10.1038/s41586-018-0035-0
https://doi.org/10.1038/s41586-018-0035-0
Autor:
Joseph D. Mancias, Jeremy F. Reiter, Timothy W. Yu, Dilenny M. Gonzalez, Jeffrey R. Johnson, Ganeshwaran H. Mochida, J. Wade Harper, Divya Jayaraman, Christopher A. Walsh, Andrew Kodani, Cristiana Vagnoni, Nevan J. Krogan, Byoung-Il Bae
Mutations in several genes encoding centrosomal proteins dramatically decrease the size of the human brain. We show that Aspm (abnormal spindle-like, microcephaly-associated) and Wdr62 (WD repeat-containing protein 62) interact genetically to control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49736df47d99ca22a4fe94bcb763e7a6
https://ora.ox.ac.uk/objects/uuid:00dadbb7-8c28-4938-a06e-3212da637a0f
https://ora.ox.ac.uk/objects/uuid:00dadbb7-8c28-4938-a06e-3212da637a0f
Autor:
Jeremy F. Reiter, Timothy W. Yu, Thong Teck Tan, Mohammad Shboul, Anas M. Alazami, Bruno Reversade, Christopher A. Walsh, Wen Fan Hu, Matthew P. Harris, Mollie B. Woodworth, Hanan Hamamy, Grace Selva Raj, Mohammed Al-Owain, Katrin Henke, Ganeshwaran H. Mochida, Amira Masri, Andrew Kodani, Muna Al Saffar, Carine Bonnard, Jennifer N. Partlow, Mohammed S. Al-Dosari, Oz Pomp, Fowzan S. Alkuraya, Tawfeg Ben-Omran
Publikováno v:
Neuron, vol 84, iss 6
Neuron, 84(6), 1240-1257. Cell Press
Neuron, 84(6), 1240-1257. Cell Press
Katanin is a microtubule-severing complex whose catalytic activities are well characterized, but whose invivo functions are incompletely understood. Human mutations in KATNB1, which encodes the noncatalytic regulatory p80 subunit of katanin, cause se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e34a72cdd2106da98ebe12237d30c44
https://doi.org/10.1016/j.neuron.2014.12.017
https://doi.org/10.1016/j.neuron.2014.12.017