Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andrew Keith Harlow Forrest"'
Autor:
Martin Everett, Michael S. Bodnarchuk, Venkatesh Kotha, Nicolas Sprynski, Narender Pottabathini, Lilha Beyria, Paduri Karunakar, Mark William Jones, Toby M G Mullins, Ramesh Ramula, T David Pallin, Sathish Kumar Martha, Jérôme Castandet, Jonathan M Sutton, Marc Lemonnier, Andrew Keith Harlow Forrest, Simon Leiris, David T. Davies, Battu Parusharamulu, Srinivasu Pothukanuri
Publikováno v:
ACS Medicinal Chemistry Letters. 12:217-227
Novel therapies are required to treat chronic bacterial infections in cystic fibrosis (CF) sufferers. The most common pathogen responsible for these infections is Pseudomonas aeruginosa, which persists within the lungs of CF sufferers despite intensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d43ca8d108ceb7eb07205d120f6775d7
https://doi.org/10.1021/acsmedchemlett.0c00554
https://doi.org/10.1021/acsmedchemlett.0c00554
Autor:
Laurent Salphati, Daniel P. Sutherlin, Binqing Wei, Jim Nonomiya, Brian Safina, Richard L. Elliott, Jodie Pang, Robert Heald, Eileen Mary Seward, Mark Ultsch, Jeremy Murray, Wenqian Yang, Andrew Keith Harlow Forrest, Steven T. Staben
Publikováno v:
ACS medicinal chemistry letters. 8(9)
A novel selective benzoxazepin inhibitor of PI3Kδ has been discovered. Beginning from compound 3, an αPI3K inhibitor, we utilized structure-based drug design and computational analysis of dihedral torsion angles to optimize for PI3Kδ isoform poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e416623d1c12d4b79901a84c2f7037
https://pubmed.ncbi.nlm.nih.gov/28947940
https://pubmed.ncbi.nlm.nih.gov/28947940