Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrew Karkhut"'
Publikováno v:
Letters in Organic Chemistry. 17:639-644
The reaction of bis-(4,6-dichloro-[1,3,5]triazin-2-yl)-diazene with furan proceeds with the formation of inverse electron demand Diels-Alder product with a high yield. M06 2X/6 31G(d,p) calculations show thermodynamic instability of “normal” DA r
Autor:
Andrew Karkhut, Anna Kryshchyshyn-Dylevych, Roman Lesyk, Myroslav Garazd, Sviatoslav Polovkovych
A mild and efficient method for the synthesis of 1-oxo-9H-thiopyrano[3,4-b]indole-3-carboxylic acids and dimerized 3-(4-carboxy-1H-3-indolyl)-2-propenoic acids via alkaline hydrolysis of 3-(rhodanin-5-yl)-1H-indole-2-carboxylic acids derivatives was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75be6e4617b79ca4dfb0a079c05efbdc
Autor:
Andrew Karkhut, Sviatoslav Polovkovych, Vadym Syngaevsky, Roman Lesyk, Volodymyr Novikov, Andrzej Gzella
Novel 2,3,4,9-tetrahydro- and 4,9-dihydro-1H-benzo[f]isoindole derivatives were synthesized from Juglone and amino-acid azomethines in 74–85% yields via 1,3-dipolar cycloaddition. The stereo- and regioselectivity of cycloaddition was confirmed by N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675c1a88c047d9b62a47b63fe22a0724
Autor:
Volodymyr Novikov, Roman Lesyk, Svyatoslav Polovkovych, Borys Zimenkovsky, Natalia G. Marintsova, Andrew Karkhut
Publikováno v:
Journal of Heterocyclic Chemistry. 50:1419-1424
New aromatic aldimines, isatine substituted ketimines based on (4,6-dichloro-1,3,5-triazin-2-yl)-hydrazine scaffold and polycyclic fused thiopyranothiazoles formed using hetero-Diels-Alder reactions starting from 4-thioxo-2-thiazolidinones and 5-norb
Autor:
Roman Lesyk, Borys Zimenkovsky, Volodymyr Novikov, Andrew Karkhut, Natalia G. Marintsova, Svyatoslav Polovkovych
Publikováno v:
ChemInform. 45
The screening of the in vitro anticancer activity of the synthesized compounds shows that compounds (IVa), (VIIIb), (VIIId) are the most active compounds against different cell lines.