Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Andrew K. Gelasco"'
Autor:
John R. Raymond, Andrew K. Gelasco
Publikováno v:
American Journal of Physiology-Renal Physiology. 290:F1551-F1558
Indoxyl sulfate is a protein metabolite that is concentrated in the serum of patients with chronic renal insufficiency. It also is a uremic toxin that has been implicated in the progression of chronic renal disease in rodent models. We have shown pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976d8a5e923401d254a592bd58fdc77a
https://doi.org/10.1152/ajprenal.00281.2004
https://doi.org/10.1152/ajprenal.00281.2004
Publikováno v:
Journal of Biological Chemistry. 279:17027-17037
The serotonin 5-HT(1A) receptor couples to heterotrimeric G proteins and intracellular second messengers, yet no studies have investigated the possible role of additional receptor-interacting proteins in 5-HT(1A) receptor signaling. We have found tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ba638d765d6df0a9f7955cd66046afa
https://doi.org/10.1074/jbc.m313919200
https://doi.org/10.1074/jbc.m313919200
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:1121-1129
Primaquine is an important antimalarial drug that is often dose-limited in therapy by the onset of hemolytic anemia. We have shown recently that an N-hydroxy metabolite of primaquine, 6-methoxy-8-hydroxylaminoquinoline (MAQ-NOH), is a direct-acting h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8259d3b8cee4e65ae1aa2a5ae165e09
https://doi.org/10.1124/jpet.102.041459
https://doi.org/10.1124/jpet.102.041459
Autor:
Justin H. Turner, Georgiann Collinsworth, Thomas W. Gettys, John R. Raymond, Jasjit S. Grewal, Maria N. Garnovskaya, Andrew K. Gelasco, Yurii V. Mukhin
Publikováno v:
Pharmacology & Therapeutics. 92:179-212
The serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into 7 subfamilies by convention, 6 of which include 13 different genes for G-protein-coupled receptors. Those subfamilies have been characterized by overlapping pharmacological pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87876b6a9b0767e64c5f29b59a3e7580
https://doi.org/10.1016/s0163-7258(01)00169-3
https://doi.org/10.1016/s0163-7258(01)00169-3
Autor:
Jarren Section, Edward L. Krug, Ricardo A. Moreno-Rodriguez, Kevin L. Schey, Andrew K. Gelasco, Angus C. Grey
Utilization of MALDI-MS (matrix-assisted laser desorption/ionization mass spectrometry) for tissue imaging is a relatively new proteomic technique that simultaneously maps the spatial distribution of multiple proteins directly within a single frozen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179848ce01862970c1578a629f09fb02
https://europepmc.org/articles/PMC3089908/
https://europepmc.org/articles/PMC3089908/
Autor:
Steven J. Christopher, Andrew K. Gelasco, Kevin Huncik, Pamela J. Riggs-Gelasco, W. Clay Davis, Peter D. R. Moeller, Kevin R. Beauchesne
Publikováno v:
Environmental sciencetechnology. 41(4)
Metal-containing organic toxins produced by Pfiesteria piscicida were characterized, for the first time, by corroborating data obtained from five distinct instrumental methods: nuclear magnetic resonance spectroscopy (NMR), inductively coupled plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc839b12f52269de4504d316fb377e7
https://pubmed.ncbi.nlm.nih.gov/17593697
https://pubmed.ncbi.nlm.nih.gov/17593697
Autor:
C. Nicole Beck, Michael E. Ullian, Wayne R. Fitzgibbon, Andrew K. Gelasco, Thomas A. Morinelli
Publikováno v:
Journal of the American Society of Nephrology : JASN. 16(8)
Antioxidants seem to inhibit angiotensin II (Ang II) actions by consuming stimulated reactive oxygen species. An alternative hypothesis was investigated: Antioxidants that are also strong reducers of disulfide bonds inhibit the binding of Ang II to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b8a8fe16050530c92dad14b2998688
https://pubmed.ncbi.nlm.nih.gov/15944340
https://pubmed.ncbi.nlm.nih.gov/15944340
Publikováno v:
Journal of the American Society of Nephrology : JASN. 15(6)
The purpose of this study was to determine the actions of oxidants on endoplasmic reticulum bound Ca(2+)-independent phospholipase A(2) (ER-iPLA(2)) and phospholipids in renal cells. Exposure of renal proximal tubule cells (RPTC) to the oxidants tert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5169384988710d5ca9340b469d0cd9b8
https://pubmed.ncbi.nlm.nih.gov/15153555
https://pubmed.ncbi.nlm.nih.gov/15153555
Publikováno v:
The Journal of biological chemistry. 279(17)
The serotonin 5-HT(1A) receptor couples to heterotrimeric G proteins and intracellular second messengers, yet no studies have investigated the possible role of additional receptor-interacting proteins in 5-HT(1A) receptor signaling. We have found tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93390a4dc79de822de80878ba0006b4d
https://pubmed.ncbi.nlm.nih.gov/14752100
https://pubmed.ncbi.nlm.nih.gov/14752100
Publisher Summary G protein-coupled receptors (GPCRs) present a challenge for mass spectrometric analysis. GPCRs, as with integral membrane proteins, in general, are more difficult to handle in terms of protein chemistry and separations than soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::067b1102b09e18846ec2730c8d54d9c6
https://doi.org/10.1016/s0076-6879(02)43132-1
https://doi.org/10.1016/s0076-6879(02)43132-1