Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Andrew K Ottens"'
Autor:
Haley E. Adcox, Jason R. Hunt, Paige E. Allen, Thomas E. Siff, Kyle G. Rodino, Andrew K. Ottens, Jason A. Carlyon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract How intracellular bacteria subvert the major histocompatibility complex (MHC) class I pathway is poorly understood. Here, we show that the obligate intracellular bacterium Orientia tsutsugamushi uses its effector protein, Ank5, to inhibit nu
Externí odkaz:
https://doaj.org/article/824e5249434245ba85ade003d5c33c0b
Autor:
Ekaterina Mostovenko, Matthew M. Dahm, Mary K. Schubauer-Berigan, Tracy Eye, Aaron Erdely, Tamara L. Young, Matthew J. Campen, Andrew K. Ottens
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Growing industrial use of carbon nanotubes and nanofibers (CNT/F) warrants consideration of human health outcomes. CNT/F produces pulmonary, cardiovascular, and other toxic effects in animals along with a significant release of bi
Externí odkaz:
https://doaj.org/article/fe3ec5b5128047a7b0e84b4924da30dd
Autor:
Tamara L. Young, Ekaterina Mostovenko, Jesse L. Denson, Jessica G. Begay, Selita N. Lucas, Guy Herbert, Katherine Zychowski, Russell Hunter, Raul Salazar, Ting Wang, Kelly Fraser, Aaron Erdely, Andrew K. Ottens, Matthew J. Campen
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Multiwalled carbon nanotubes (MWCNT) are an increasingly utilized engineered nanomaterial that pose the potential for significant risk of exposure-related health outcomes. The mechanism(s) underlying MWCNT-induced toxicity to extr
Externí odkaz:
https://doaj.org/article/254eda78fcc34280af3ce8c513a04754
Autor:
Ekaterina Mostovenko, Tamara Young, Pretal P. Muldoon, Lindsey Bishop, Christopher G. Canal, Aleksandar Vucetic, Patti C. Zeidler-Erdely, Aaron Erdely, Matthew J. Campen, Andrew K. Ottens
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-23 (2019)
Abstract Background The mechanisms driving systemic effects consequent pulmonary nanoparticle exposure remain unclear. Recent work has established the existence of an indirect process by which factors released from the lung into the circulation promo
Externí odkaz:
https://doaj.org/article/896acf3c8ab74e79bbd17ce1d0010576
Autor:
Tamara L. Young, David Scieszka, Jessica G. Begay, Selita N. Lucas, Guy Herbert, Katherine Zychowski, Russell Hunter, Raul Salazar, Andrew K. Ottens, Aaron Erdely, Haiwei Gu, Matthew J. Campen
Publikováno v:
Inhalation Toxicology. 35:86-100
Environmental exposures exacerbate age-related pathologies, such as cardiovascular and neurodegenerative diseases. Nanoparticulates, and specifically carbon nanomaterials, are a fast-growing contributor to the category of inhalable pollutants, whose
Autor:
Selita Lucas, Jesse L. Denson, Ting Wang, Jessica Begay, Tamara L. Young, Guy Herbert, Katherine E. Zychowski, Aaron Erdely, Raul Salazar, Andrew K. Ottens, Kelly Fraser, Russell Hunter, Matthew J. Campen, Ekaterina Mostovenko
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Particle and Fibre Toxicology
Particle and Fibre Toxicology
Background Multiwalled carbon nanotubes (MWCNT) are an increasingly utilized engineered nanomaterial that pose the potential for significant risk of exposure-related health outcomes. The mechanism(s) underlying MWCNT-induced toxicity to extrapulmonar
Autor:
Jillian E. Stafflinger, Andrew K. Ottens, Parantap D Patel, Jennifer H. Marwitz, Janet P. Niemeier
Publikováno v:
Neurorehabilitation and Neural Repair. 35:169-184
Background Rehabilitation following traumatic brain injury (TBI) significantly improves outcomes; yet TBI heterogeneity raises the need for molecular evidence of brain recovery processes to better track patient progress, evaluate therapeutic efficacy
Autor:
Jesse L. Denson, Selita Lucas, Guy Herbert, Tamara L. Young, Barry E. Bleske, Matthew J. Campen, Jessica Begay, Raul Salazar, Andrew K. Ottens, Samuel G. Mackintosh, Ryan L. Ashley, Stephanie D. Byrum, Thomas B Wilson, Marcus Garcia, Katherine E. Zychowski
Publikováno v:
Toxicol Sci
Exposure to air pollutants such as ozone (O3) is associated with adverse pregnancy outcomes, including higher incidence of gestational hypertension, preeclampsia, and peripartum cardiomyopathy; however, the underlying mechanisms of this association r
Autor:
David Scieszka, Russell Hunter, Jessica Begay, Marsha Bitsui, Yan Lin, Joseph Galewsky, Masako Morishita, Zachary Klaver, James Wagner, Jack R Harkema, Guy Herbert, Selita Lucas, Charlotte McVeigh, Alicia Bolt, Barry Bleske, Christopher G Canal, Ekaterina Mostovenko, Andrew K Ottens, Haiwei Gu, Matthew J Campen, Shahani Noor
Publikováno v:
Toxicol Sci
Utilizing a mobile laboratory located >300 km away from wildfire smoke (WFS) sources, this study examined the systemic immune response profile, with a focus on neuroinflammatory and neurometabolomic consequences, resulting from inhalation exposure to
Autor:
Mary K. Schubauer-Berigan, Matthew M. Dahm, Aaron Erdely, Andrew K. Ottens, Tracy Eye, Matthew J. Campen, Ekaterina Mostovenko, Tamara L. Young
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-16 (2021)
Background Growing industrial use of carbon nanotubes and nanofibers (CNT/F) warrants consideration of human health outcomes. CNT/F produces pulmonary, cardiovascular, and other toxic effects in animals along with a significant release of bioactive p