Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew K Mason"'
Autor:
Alexis M, Ziemba, Keith P, Lane, Ignacio M, San Segundo, Anthony R, D'Amato, Andrew K, Mason, Ryan J, Sexton, Hubert, Casajus, Richard A, Gross, David T, Corr, Ryan J, Gilbert
Publikováno v:
ACS biomaterials scienceengineering. 4(5)
Electrospun poly-l-lactic acid (PLLA) fiber scaffolds are used to direct axonal extension in neural engineering models. We aimed to improve the efficacy of these fibers in promoting neurite outgrowth by altering surface topography and reducing fiber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e981028e52f4af91fe1d895552414ea8
https://pubmed.ncbi.nlm.nih.gov/33445306
https://pubmed.ncbi.nlm.nih.gov/33445306
Autor:
Ignacio Martinez San Segundo, Richard A. Gross, Ryan J. Gilbert, Alexis M. Ziemba, Anthony R. D’Amato, Andrew K. Mason, Ryan J Sexton, Hubert Casajus, Keith P. Lane, David T. Corr
Publikováno v:
ACS Biomaterials Science & Engineering.
Electrospun poly-l-lactic acid (PLLA) fiber scaffolds are used to direct axonal extension in neural engineering models. We aimed to improve the efficacy of these fibers in promoting neurite outgrowth by altering surface topography and reducing fiber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff4e6bc957027df785225fd2b196512
https://doi.org/10.1021/acsbiomaterials.8b00013
https://doi.org/10.1021/acsbiomaterials.8b00013
Autor:
Michelle R. Lennartz, Anthony R. D’Amato, Ryan J. Gilbert, Erin Y. Harmon, Nicholas J. Schaub, David T. Corr, Andrew K. Mason
Publikováno v:
Journal of biomaterials science. Polymer edition. 28(13)
Currently, it is unknown how the mechanical properties of electrospun fibers, and the presentation of surface nanotopography influence macrophage gene expression and protein production. By further elucidating how specific fiber properties (mechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f68d49967ea1e06c00da31f0e30f2c
https://pubmed.ncbi.nlm.nih.gov/28420296
https://pubmed.ncbi.nlm.nih.gov/28420296
Autor:
Laurent Salphati, Eric Sands, Praveen Balimane, Caroline A. Lee, Johan E. Palm, Joe Bentz, Lalitha Podila, Jesse Taur, Tetsuo Yamagata, Lei K. Zhang, Kathleen M. Hillgren, Eric L. Reyner, Marie Brännström, Dietmar Weitz, Emile Plise, Jocelyn Yabut, Masoud Jamei, Harma Ellens, Anne Pak, Dallas Bednarczyk, Guangqing Xiao, Mitchell E. Taub, Libin Li, Heleen M. Wortelboer, Elke S Perloff, Andrew K Mason, Michael P. O'Connor, Krisztina Herédi-Szabó, Aarti Patel, Ganesh Rajaraman, Xiaoyan Chu, Evelyn Hollnack-Pusch, Christoph Funk, Joann Coleman, Cindy Q. Xia, Xuena Lin, Imad Hanna, Ailan Guo, Sibylle Neuhoff
Publikováno v:
Drug Metabolism and Disposition. 41:1347-1366
A P-glycoprotein (P-gp) IC₅₀ working group was established with 23 participating pharmaceutical and contract research laboratories and one academic institution to assess interlaboratory variability in P-gp IC₅₀ determinations. Each laboratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d287357bc8fa4a0193383933cbb55d1a
https://doi.org/10.1124/dmd.112.050500
https://doi.org/10.1124/dmd.112.050500
Autor:
Ritu Singh, Andrew P. Blanchard, Eric Gangl, Shangara S. Dehal, Timothy P Creegan, David M. Stresser, Andrew K Mason, Elke S Perloff
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 44(8)
The sedative clomethiazole (CMZ) has been used in Europe since the mid-1960s to treat insomnia and alcoholism. It has been previously demonstrated in clinical studies to reversibly inhibit human CYP2E1 in vitro and decrease CYP2E1-mediated eliminatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8899cf80542ce48b86c940728fdcaf8
https://pubmed.ncbi.nlm.nih.gov/27149898
https://pubmed.ncbi.nlm.nih.gov/27149898
Autor:
L. Morgan, N. Boily, T. Ho, Elke S Perloff, C. M. Chandler, Charles L. Crespi, Andre A. Dandeneau, David M. Stresser, R. M. Crocker, Shangara S. Dehal, Andrew P. Blanchard, Andrew K Mason
Publikováno v:
Xenobiotica. 39:99-112
1. Recent guidance from the US Food and Drug Administration (USFDA) has advocated testing of time-dependent inhibition of cytochrome P450 (CYP), which can be addressed by performing IC(50) shift as well as K(I)/k(inact) determinations. 2. Direct (IC(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df3676ccd47fdcd6264a0ca88f8ebb5
https://doi.org/10.1080/00498250802638155
https://doi.org/10.1080/00498250802638155
Autor:
Thuy Ho, David M. Stresser, Shangara S. Dehal, Andre A. Dandeneau, Charles L. Crespi, Ling Morgan, Elke S Perloff, Andrew K Mason
Publikováno v:
Drug Metabolism and Disposition. 37:695-698
Fluoxetine [+/--N-methyl-3-phenyl-3-[(alpha, alpha, (-trifluoro-p-tolyl)oxy]-propylamine)] a selective serotonin reuptake inhibitor, is widely used in treating depression and other serotonin-dependent disease conditions. Racemic, (R)- and (S)-fluoxet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9a00176d3bd7f9dd6f398c9d156009
https://doi.org/10.1124/dmd.108.025726
https://doi.org/10.1124/dmd.108.025726
Publikováno v:
Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions.
Skeletal muscle loss, through injuries, myopathies, and interventional medicine, presents major challenges in physiological function and clinical interventions [1]. Autologous tissue transplantation necessitates tissue loss from the donor site, and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a062c14df2206d2ebbe75114c4b97bd6
https://doi.org/10.1115/sbc2013-14646
https://doi.org/10.1115/sbc2013-14646
Publikováno v:
Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions.
Normal organ development, function, and repair are coordinated by interactions between the epithelium and the surrounding stromal cell populations. Cellular function and homeostasis are controlled by an array of chemical and physical cues originating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d05652e3b2aae7d569cbb22c63242fd0
https://doi.org/10.1115/sbc2013-14600
https://doi.org/10.1115/sbc2013-14600
Autor:
Dan A. Rock, Michael G. Johnson, Xiaoqi Chen, Simon Wong, Bradley K. Wong, George Tonn, Brooke M. VandenBrink, Yohannes Teffera, Raju Subramanian, Thuy B. Tran, David M. Stresser, Kirk Henne, Andrew K Mason, Divesh Aidasani
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 40(7)
CYP3A4-mediated biotransformation of (R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(pyridin-3-ylmethyl)-2-(4-(trifluoromethoxy)phenyl)acetamide (AMG 487) was previously shown to generate an inhibitory metabolite l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e511622be663bb3203009279a0e395eb
https://pubmed.ncbi.nlm.nih.gov/22517972
https://pubmed.ncbi.nlm.nih.gov/22517972