Isolation and characterisation of Leishmania donovani protein antigens from urine of visceral leishmaniasis patients.

Autor: Tegwen Marlais, Tapan Bhattacharyya, Callum Pearson, Bathsheba L Gardner, Safiyyah Marhoon, Stephanie Airs, Kiera Hayes, Andrew K Falconar, Om Prakash Singh, Steven G Reed, Sayda El-Safi, Shyam Sundar, Michael A Miles

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0238840 (2020)

Diagnosis of visceral leishmaniasis (VL) relies on invasive and risky aspirate procedures, and confirmation of cure after treatment is unreliable. Detection of Leishmania donovani antigens in urine has the potential to provide both a non-invasive dia

Externí odkaz: https://doaj.org/article/ad6c1be4829b439387e5d0b9f3086143

Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition.

Autor: Tapan Bhattacharyya, Andrew K Falconar, Alejandro O Luquetti, Jaime A Costales, Mario J Grijalva, Michael D Lewis, Louisa A Messenger, Trang T Tran, Juan-David Ramirez, Felipe Guhl, Hernan J Carrasco, Patricio Diosque, Lineth Garcia, Sergey V Litvinov, Michael A Miles

Publikováno v: PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2892 (2014)

BACKGROUND: Chagas disease, caused by infection with the protozoan Trypanosoma cruzi, remains a serious public health issue in Latin America. Genetically diverse, the species is sub-divided into six lineages, known as TcI-TcVI, which have disparate g

Externí odkaz: https://doaj.org/article/ec4f2ea7e2cf40088c643b06dc030853

Evaluation of Zika rapid tests as aids for clinical diagnosis and epidemic preparedness

Autor: Debi Boeras, Cheikh Tidiane Diagne, Jose L. Pelegrino, Marc Grandadam, Veasna Duong, Philippe Dussart, Paul Brey, Didye Ruiz, Marisa Adati, Annelies Wilder-Smith, Andrew K. Falconar, Claudia M. Romero, Maria Guzman, Nagwa Hasanin, Amadou Sall, Rosanna W. Peeling

Publikováno v: EClinicalMedicine, Vol 49, Iss , Pp 101478- (2022)

Summary: Background: Development and evaluation of diagnostics for diseases of epidemic potential are often funded during epidemics, but not afterwards, leaving countries unprepared for the next epidemic. United Nations Children's Emergency Fund (UNI

Externí odkaz: https://doaj.org/article/472ff7e21d114ce4b1be35c53bbf9213

Leptospira spp. y leptospirosis humana

Autor: Claudia M. Romero-Vivas, Andrew K. Falconar

Publikováno v: Salud Uninorte, Vol 32, Iss 1, Pp 123-143 (2016)

La leptospirosis, la enfermedad bacteriana zoonótica y emergente más importante en el mundo, es causada por las especies patógenas de Leptospira spp. Han sido descritas veinte especies de Leptospira spp.; se ha determinado la secuencia del ADN gen

Externí odkaz: https://doaj.org/article/52f4b360227141a7a51b484e0c9121de

Visceral Leishmaniasis IgG1 Rapid Monitoring of Cure vs. Relapse, and Potential for Diagnosis of Post Kala-Azar Dermal Leishmaniasis

Autor: Tegwen Marlais, Tapan Bhattacharyya, Om Prakash Singh, Pascal Mertens, Quentin Gilleman, Caroline Thunissen, Bruno C. Bremer Hinckel, Callum Pearson, Bathsheba L. Gardner, Stephanie Airs, Marianne de la Roche, Kiera Hayes, Hannah Hafezi, Andrew K. Falconar, Osama Eisa, Alfarazdeg Saad, Basudha Khanal, Narayan Raj Bhattarai, Suman Rijal, Marleen Boelaert, Sayda El-Safi, Shyam Sundar, Michael A. Miles

Publikováno v: Frontiers in Cellular and Infection Microbiology
Frontiers in cellular and infection microbiology
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)

Background: There is a recognized need for an improved diagnostic test to assess post-chemotherapeutic treatment outcome in visceral leishmaniasis (VL) and to diagnose post kala-azar dermal leishmaniasis (PKDL). We previously demonstrated by ELISA an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9be33f52f97026e0a0c7dcac34ffa2
http://europepmc.org/articles/PMC6300496