Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew K, Turner"'
Publikováno v:
Genes. 13(9)
Elucidating the actions of genetic polymorphisms associated with the risk of Alzheimer's disease (AD) may provide novel insights into underlying mechanisms. Two polymorphisms have implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::092c7813423b31c6c192e1693918a90a
https://pubmed.ncbi.nlm.nih.gov/36140776
https://pubmed.ncbi.nlm.nih.gov/36140776
An Alternatively Spliced TREM2 Isoform Lacking the Ligand Binding Domain is Expressed in Human Brain
Autor:
Benjamin C. Shaw, Henry C. Snider, Andrew K. Turner, Diana J. Zajac, James F. Simpson, Steven Estus
Publikováno v:
J Alzheimers Dis
Background: Genetic variants in TREM2 are strongly associated with Alzheimer’s disease (AD) risk but alternative splicing in TREM2 transcripts has not been comprehensively described. Objective: Recognizing that alternative splice variants can resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854e8ad2d84eeafaf45364ffaf5dce05
https://pubmed.ncbi.nlm.nih.gov/35527547
https://pubmed.ncbi.nlm.nih.gov/35527547
Autor:
Joseph A Jackson, Amy J Hall, Ida M Friberg, Catriona Ralli, Ann Lowe, Malgorzata Zawadzka, Andrew K Turner, Alexander Stewart, Richard J Birtles, Steve Paterson, Janette E Bradley, Mike Begon
Publikováno v:
PLoS Biology, Vol 12, Iss 7, p e1001901 (2014)
Hosts are likely to respond to parasitic infections by a combination of resistance (expulsion of pathogens) and tolerance (active mitigation of pathology). Of these strategies, the basis of tolerance in animal hosts is relatively poorly understood, w
Externí odkaz:
https://doaj.org/article/32f0f91d0a234beab6d95f3349f12eec
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002343 (2011)
Pathogens are believed to drive genetic diversity at host loci involved in immunity to infectious disease. To date, studies exploring the genetic basis of pathogen resistance in the wild have focussed almost exclusively on genes of the Major Histocom
Externí odkaz:
https://doaj.org/article/6a7fda7ae5ae41fba47a30059190d177
Autor:
Christopher H. Taylor, Michael Begon, Steve Paterson, Anna G. Thomason, Ida M. Friberg, Janette E. Bradley, Richard J. Birtles, Klara M. Wanelik, Andrew K. Turner, Joseph A. Jackson
The animal immune response has hitherto been viewed primarily in the context of resistance only. However, individuals, can also employ a tolerance strategy to maintain good health in the face of on-going infection. To shed light on the genetic and ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5229bc3f45a59eb5b615879ac09cecd8
https://usir.salford.ac.uk/id/eprint/44525/8/Wanelik_et_al-2018-Molecular_Ecology.pdf
https://usir.salford.ac.uk/id/eprint/44525/8/Wanelik_et_al-2018-Molecular_Ecology.pdf
Publikováno v:
Molecular Ecology. 21:1632-1646
Individuals in natural populations are frequently exposed to a wide range of pathogens. Given the diverse profile of gene products involved in responses to different types of pathogen, this potentially results in complex pathogen-specific selection p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a0c0268bdb4ef98ff53b714a005149e
https://doi.org/10.1111/j.1365-294x.2012.05501.x
https://doi.org/10.1111/j.1365-294x.2012.05501.x
Autor:
Catriona Ralli, Richard J. Birtles, Andrew K. Turner, Joseph A. Jackson, Michael Begon, Malgorzata Zawadzka, Ann Lowe, Ida M. Friberg, Amy Hall, Janette E. Bradley, Steve Paterson
Publikováno v:
Molecular Ecology. 20:893-909
Special Issue: FRONTIERS IN HOST-PARASITE ECOLOGY AND EVOLUTION Jackson, J. A., Begon, M., Birtles, R., Paterson, S., Friberg, I. M., Hall, A., Lowe, A., Ralli, C., Turner, A., Zawadzka, M., Bradley, J. E. (2011). The analysis of immunological profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3c48a3a70ddb25a1bb6840a17f50f98
https://doi.org/10.1111/j.1365-294x.2010.04907.x
https://doi.org/10.1111/j.1365-294x.2010.04907.x
Autor:
Andrew K. Turner, Steve Paterson
Publikováno v:
Parasite Immunology.
Individuals vary in their susceptibility to infectious disease, and it is now well established that host genetic factors form a major component of this variation. The discovery of genes underlying susceptibility has the potential to lead to improved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9c09f64d0e8428186ba30c702ea283
https://doi.org/10.1111/pim.12036
https://doi.org/10.1111/pim.12036
Publikováno v:
Molecular ecology. 21(7)
Individuals in natural populations are frequently exposed to a wide range of pathogens. Given the diverse profile of gene products involved in responses to different types of pathogen, this potentially results in complex pathogen-specific selection p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33a4cb9203c0616ca20a22a063c0038a
https://pubmed.ncbi.nlm.nih.gov/22364125
https://pubmed.ncbi.nlm.nih.gov/22364125
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 10, p e1002343 (2011)
PLoS Genetics, Vol 7, Iss 10, p e1002343 (2011)
Pathogens are believed to drive genetic diversity at host loci involved in immunity to infectious disease. To date, studies exploring the genetic basis of pathogen resistance in the wild have focussed almost exclusively on genes of the Major Histocom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a60158b352f291e4accdbd445c204b2
https://pubmed.ncbi.nlm.nih.gov/22039363
https://pubmed.ncbi.nlm.nih.gov/22039363