Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrew Jarratt"'
BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation
Autor:
Andrew Keniry, Natasha Jansz, Linden J. Gearing, Iromi Wanigasuriya, Joseph Chen, Christian M. Nefzger, Peter F. Hickey, Quentin Gouil, Joy Liu, Kelsey A. Breslin, Megan Iminitoff, Tamara Beck, Andres Tapia del Fierro, Lachlan Whitehead, Andrew Jarratt, Sarah A. Kinkel, Phillippa C. Taberlay, Tracy Willson, Miha Pakusch, Matthew E. Ritchie, Douglas J. Hilton, Jose M. Polo, Marnie E. Blewitt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Female embryonic stem cells (ESCs) are the ideal model to study X chromosome inactivation (XCI) establishment; however, these cells are challenging to keep in culture. Here the authors create fluorescent ‘Xmas’ reporter mice as a renewable source
Externí odkaz:
https://doaj.org/article/55d8f97f36464af78639b6d7c2a5c371
Autor:
Judith Schütte, Huange Wang, Stella Antoniou, Andrew Jarratt, Nicola K Wilson, Joey Riepsaame, Fernando J Calero-Nieto, Victoria Moignard, Silvia Basilico, Sarah J Kinston, Rebecca L Hannah, Mun Chiang Chan, Sylvia T Nürnberg, Willem H Ouwehand, Nicola Bonzanni, Marella FTR de Bruijn, Berthold Göttgens
Publikováno v:
eLife, Vol 5 (2016)
Transcription factor (TF) networks determine cell-type identity by establishing and maintaining lineage-specific expression profiles, yet reconstruction of mammalian regulatory network models has been hampered by a lack of comprehensive functional va
Externí odkaz:
https://doaj.org/article/1de7a5bf09f74bf7bca63a4f8f5adab5
Autor:
Matthew P. McCormack, Sara Tomei, Olivia Stonehouse, Adrienne A. Hilton, Matthew E. Ritchie, Andrew Jarratt, Dawn S. Lin, Warren S. Alexander, Samir Taoudi, Mark D. McKenzie, Stephen L. Nutt, Jaring Schreuder, Ashley P. Ng, Shalin H. Naik, Ladina Di Rago, Daniela Amann-Zalcenstein, Jacob T. Jackson, Jessica E. Bolden, Carolyn A. de Graaf, Kirsten A. Fairfax, Luyi Tian
Publikováno v:
Nature Immunology. 21:1574-1584
A classical view of blood cell development is that multipotent hematopoietic stem and progenitor cells (HSPCs) become lineage-restricted at defined stages. Lin-c-Kit+Sca-1+Flt3+ cells, termed lymphoid-primed multipotent progenitors (LMPPs), have lost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4caa15b473124e6d02b7011f0da5dd7c
https://doi.org/10.1038/s41590-020-0799-x
https://doi.org/10.1038/s41590-020-0799-x
Publikováno v:
Cytokine. 146:155624
Interleukin 6 is the classical member of the IL-6 family of cytokines which triggers activation of the JAK/STAT signaling cascade in cells. IL-6 is a pleiotropic cytokine that acts on many cell types and plays a critical role in immune responses, inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc81bbf00ee9a4705e07bbb788925f0
https://doi.org/10.1016/j.cyto.2021.155624
https://doi.org/10.1016/j.cyto.2021.155624
Autor:
Shalin Naik, Luyi Tian, Sara Tomei, Jaring Schreuder, Tom Weber, Daniela Amman-Zalcenstein, Dawn Lin, Jessica Tran, Cindy Audiger, Melanie Bahlo, Mathew Chu, Peter Diakumis, Quentin Gouil, Adrienne Hilton, Andrew Jarratt, Tracy Willson, Lev Kats, Madison kelly, Ee Shan Pang, Meredith O'Keeffe, Timothy Patton, Tobias Sargeant, Shian Su, Philip Hodgkin, Ashley Ng, Matthew Ritchie
Publikováno v:
Experimental Hematology. 100:S92
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2257930456c7a8939d741f02202ca5b
https://doi.org/10.1016/j.exphem.2021.12.321
https://doi.org/10.1016/j.exphem.2021.12.321
Autor:
Lev Kats, Peter Diakumis, Timothy Patton, Sara Tomei, Cindy Audiger, Meredith O'Keeffe, Toby Sargeant, Shalin H. Naik, Daniela Amann-Zalcenstein, Jessica Tran, Melanie Bahlo, Ee Shan Pang, Luyi Tian, Matthew E. Ritchie, Dawn S. Lin, Ashley P. Ng, Madison J. Kelly, Adrienne A. Hilton, Andrew Jarratt, Tracy A. Willson, Jaring Schreuder, Tom S. Weber, Quentin Gouil, Mathew Chu, Philip D. Hodgkin, Shian Su
Publikováno v:
Immunity. 54:1338-1351.e9
Despite advances in single-cell multi-omics, a single stem or progenitor cell can only be tested once. We developed clonal multi-omics, in which daughters of a clone act as surrogates of the founder, thereby allowing multiple independent assays per c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0c7e9bb4e4b72fe8b7e1116b15c705
https://doi.org/10.1016/j.immuni.2021.03.012
https://doi.org/10.1016/j.immuni.2021.03.012
Autor:
Daniela, Amann-Zalcenstein, Luyi, Tian, Jaring, Schreuder, Sara, Tomei, Dawn S, Lin, Kirsten A, Fairfax, Jessica E, Bolden, Mark D, McKenzie, Andrew, Jarratt, Adrienne, Hilton, Jacob T, Jackson, Ladina, Di Rago, Matthew P, McCormack, Carolyn A, de Graaf, Olivia, Stonehouse, Samir, Taoudi, Warren S, Alexander, Stephen L, Nutt, Matthew E, Ritchie, Ashley P, Ng, Shalin H, Naik
Publikováno v:
Nature immunology. 21(12)
A classical view of blood cell development is that multipotent hematopoietic stem and progenitor cells (HSPCs) become lineage-restricted at defined stages. Lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4907eb136484612c74aac4efa521bca
https://pubmed.ncbi.nlm.nih.gov/33077975
https://pubmed.ncbi.nlm.nih.gov/33077975
DACH1 DOWNREGULATION DELINEATE A LYMPHOID PRIMED PROGENITOR (LPP) POPULATION WITHIN THE MPP4 CLUSTER
Autor:
Sara Tomei, Mark D. McKenzie, Shalin H. Naik, Matt McCormack, Jacob T. Jackson, D J Hilton, Ashley P. Ng, Adrienne A. Hilton, Andrew Jarratt, Ladina Di Rago, Luyi Tian, Matthew E. Ritchie, Daniela Zalcenstein, Dawn S. Lin, Ben Shields, Jaring Schreuder
Publikováno v:
Experimental Hematology. 76:S89
Classical models of haematopoiesis dictate that a single hematopoietic stem cell (HSC) with self-renewal capacity can give rise to all the hematopoietic lineage through subsequent division and loss of potential. This loss of potential is captured thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c05a3e91359be7c70d6b8a7d990cd1be
https://doi.org/10.1016/j.exphem.2019.06.448
https://doi.org/10.1016/j.exphem.2019.06.448
Publikováno v:
Proceedings of the Institution of Civil Engineers - Energy. 166:58-66
Foamed grout has been used extensively to backfill disused coal mines, but with densities of between 1000 and 2000 kg/m3. This report describes how two lightweight grouts having densities of 500 and 300 kg/m3 were developed and deployed in order to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bc970aa30a80d2ab0463e4b1448eee
https://doi.org/10.1680/ener.12.00001
https://doi.org/10.1680/ener.12.00001
Autor:
Eddy Rubin, Caroline L. Speck, Pik-Shan Li, John Kong-a-San, Matthew Burgess, Andrew Jarratt, Marella F. T. R. de Bruijn, Wade T. Nottingham, Shyam Prabhakar, Jan Fang Cheng, Jackie Sloane-Stanley
The transcription factor Runx1/AML1 is an important regulator of hematopoiesis and is critically required for the generation of the first definitive hematopoietic stem cells (HSCs) in the major vasculature of the mouse embryo. As a pivotal factor in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d62f61d1b4e214e1ef280a6e1b6094
https://ora.ox.ac.uk/objects/uuid:d1babc62-db8d-4f7c-be6a-53c10ee203dd
https://ora.ox.ac.uk/objects/uuid:d1babc62-db8d-4f7c-be6a-53c10ee203dd
