Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Andrew James Godkin"'
Publikováno v:
Trends in Cancer. 7:214-225
Secondary lymphoid organs (SLOs) are important initiators and regulators of immunity. To carry out this function, the blood vasculature must deliver oxygen and nutrients and recruit circulating lymphocytes into the SLO parenchyma, where they encounte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f9cc799c3f36afbc3b7fc75e3825e6
https://doi.org/10.1016/j.trecan.2020.10.001
https://doi.org/10.1016/j.trecan.2020.10.001
Autor:
Georgina H. Mason, David K. Cole, Frédéric Triebel, Awen Gallimore, Andrew James Godkin, Bruce J. MacLachlan, Alexander Greenshields-Watson
Publikováno v:
European Journal of Immunology
Immune checkpoint inhibitors (antibodies that block the T cell co‐inhibitory receptors PD‐1/PD‐L1 or CTLA‐4) have revolutionized the treatment of some forms of cancer. Importantly, combination approaches using drugs that target both pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295dfce87346771adca4707fe21a976b
https://doi.org/10.1002/eji.202048753
https://doi.org/10.1002/eji.202048753
Autor:
Andrew James Godkin, Andrew Blainey, Anja Bloom, Sarah Nicol Lauder, Jake Scott, Awen Gallimore, Emma Jones, Molly Browne, E. Hughes, Michelle Somerville, Ann Ager, Kathryn Smart
Publikováno v:
Cancer Immunology, Immunotherapy
Although metastatic disease is responsible for the majority of cancer deaths, tests of novel immunotherapies in mouse tumour models often focus on primary tumours without determining whether these therapies also target metastatic disease. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7823a107573420715c577954336cabb3
https://doi.org/10.1007/s00262-020-02603-x
https://doi.org/10.1007/s00262-020-02603-x
Autor:
Andrew James Godkin, Gillian Ingram, Randy Chance, Katharine Harding, Ruth Dobson, David Baker, Klaus Schmierer, Nikos Evangelou, Gavin Giovannoni, Kath Bramhall, Aimee Hibbert, Martin J. Scurr, Jessica Simmons, Mark Willis, Samantha Loveless, Matthew Upcott, Katila George, Aliye Nazli Asardag, Meleri Jones, Jonathan P. Bestwick, Leanne Grant, Valerie Anderson, Angray S. Kang, Sita Navin Shah, Stuart J. Moat, Neil Robertson, Stephen Jolles, Nicola Vickaryous, Emma C. Tallantyre
Publikováno v:
Annals of Neurology
Objective The purpose of this study was to investigate the effect of disease modifying therapies on immune response to severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) vaccines in people with multiple sclerosis (MS). Methods Four hundred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0b1f56ba31cf4c0cee96d4e9bc9666
https://nottingham-repository.worktribe.com/file/6729552/1/ana.26251
https://nottingham-repository.worktribe.com/file/6729552/1/ana.26251
Autor:
Charlotte Young, Lucy C. Fairclough, Andrew D. Westwell, Kerry Roberts, Kate Davies, Thomas Tozer, Stephanie E A Burnell, Paddy Tighe, Tara Rees, Amanda Jackson, B. Paul Morgan, Awen Gallimore, Martin J. Scurr, Michelle Somerville, Mererid Evans, Andrew James Godkin, George Lippiatt, Wioleta M. Zelek, Mark R. Wills, Helen Lawton, Lorenzo Capitani
Publikováno v:
Immunology
Accurate assessment of SARS‐CoV‐2 immunity is critical in evaluating vaccine efficacy and devising public health policies. Whilst the exact nature of effective immunity remains incompletely defined, SARS‐CoV‐2‐specific T‐cell responses ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d98df614d6784a18360ac8e997abea
http://europepmc.org/articles/PMC8653009
http://europepmc.org/articles/PMC8653009
Autor:
Andrew James Godkin, Alan L. Parker, Elise Moses, Rebecca J. Bayliss, Georgina H. Mason, Alicia Teijeira Crespo, Lorenzo Capitani, Awen Gallimore, James A. Davies, Stephanie E A Burnell
Publikováno v:
Immunology
Oncolytic viruses possess the ability to infect, replicate and lyse malignantly transformed tumour cells. This oncolytic activity amplifies the therapeutic advantage and induces a form of immunogenic cell death, characterized by increased CD8 + T‐c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8914e2f9ae1ff06e891522d1b1dce3ca
Autor:
Thomas Tozer, Kate Davies, Lucy C. Fairclough, Martin J. Scurr, Michelle Somerville, Kerry Roberts, Andrew James Godkin, Mererid Evans, George Lippiatt, Andrew D. Westwell, Tara Rees, Mark R. Wills, Helen Lawton, Stephanie E A Burnell, Awen Gallimore, Amanda Jackson, Wioleta M. Zelek, Lorenzo Capitani, Charlotte Aimee Young, B. Paul Morgan
Accurate assessment of SARS-CoV-2 immunity in the population is critical to evaluating vaccine efficacy and devising public health policies. Whilst the exact nature of effective immunity remains incompletely defined, SARS-CoV-2-specific T cell respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c11330d1aecb09fe1f9bfa9265e9e1
https://doi.org/10.1101/2021.06.02.21258218
https://doi.org/10.1101/2021.06.02.21258218
Autor:
Andrew James Godkin, Michael P. Manns, Ye Htun Oo, Nwe Ni Than, Meemee Botter, James Hodson, David H. Adams, Mark G. Swain, Rebecca E. Wawman, Daniel Schmidt-Martin, Kelly W. Burak, Aldo J. Montano-Loza, Richard Taubert, Rebecca L Jones, Gautham D Appanna, Frank Lammert, Nishant Gautam, Christoph Schramm, Gideon M. Hirschfield, Kilian Bock
Publikováno v:
JHEP Reports
JHEP Reports, Vol 1, Iss 6, Pp 437-445 (2019)
JHEP reports
JHEP Reports, Vol 1, Iss 6, Pp 437-445 (2019)
JHEP reports
Background & Aims Treatment options remain limited for patients with autoimmune hepatitis (AIH), while there are still concerns over the consequences of long-term corticosteroid use. A few studies have suggested a role for B cell-driven autoimmune li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5f5e6f4134dc01f06e7916837491c6
http://europepmc.org/articles/PMC7005655
http://europepmc.org/articles/PMC7005655
Autor:
Kathryn Smart, Andrew James Godkin, Stefan Milutinovic, Sarah Nicol Lauder, Awen Gallimore, Ana Pires
Publikováno v:
Methods in Cell Biology ISBN: 9780128225349
Mouse models of cancer are essential in furthering our understanding both of the mechanisms that drive tumor development and the immune response that develops in parallel, and also in providing a platform for testing novel anti-cancer therapies. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00fa511cd046aeab045189f804073446
https://doi.org/10.1016/bs.mcb.2020.09.007
https://doi.org/10.1016/bs.mcb.2020.09.007
Autor:
Emma Jones, Rhiannon French, William J. Watkins, Matthew J. Smalley, Alexander Greenshields-Watson, James P. Hindley, Awen Gallimore, Sarah N. Lauder, Michelle Somerville, Robert Andrews, Andrew James Godkin, Kathryn Smart, Stefan Milutinovic, Ana Pires, Howard Kendrick
Publikováno v:
Cancer Immunol Res
The nature of the tumor microenvironment (TME) influences the ability of tumor-specific T cells to control tumor growth. In this study, we performed an unbiased comparison of the TME of regulatory T-cell (Treg)–replete and Treg-depleted carcinogen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c12cfa716e73b409f397bccf382eb36
https://europepmc.org/articles/PMC7611107/
https://europepmc.org/articles/PMC7611107/