Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Andrew J.M. Nel"'
Autor:
Clemens Hermann, Alexander D. Giddey, Andrew J.M. Nel, Nelson C. Soares, Jonathan M. Blackburn
Publikováno v:
MethodsX, Vol 5, Iss , Pp 475-484 (2018)
The comprehensive characterisation of the cell wall proteome of mycobacteria is of considerable relevance to both the discovery of new drug targets as well as to the design of new vaccines against Mycobacterium tuberculosis. However, due to its extre
Externí odkaz:
https://doaj.org/article/27321a622f864be680ca486b007bb655
Autor:
Leshern Karamchand, Andrew J.M. Nel, Jonathan M. Blackburn, David W. Wright, Megan van der Horst, Westley S. Bauer
Publikováno v:
The Analyst
Tuberculosis (TB) is one of the top ten causes of death globally, despite being treatable. The eradication of TB disease requires, amongst others, diagnostic tests with high specificity and sensitivity that will work at the point of care (POC) in low
Autor:
Nishant N. Vaikath, Khalid Ouararhni, Wendy A. Burgers, Adviti Naik, Elizabeth S Mayne, Nur Hafiza Ismail, Michelle Mullins, Darien T. Schell, Omar M. A. El-Agnaf, Nur Diana Anuar, Mohammed Al-Maadheed, Maryam Ali Al-Nesf, Kavithambigai Ellan, Ilham Bensmail, Arif Anwar, Nurul Shielawati Mohamed Rosli, Nour K. Majbour, Vidya Mohamed-Ali, Priscilla E. Morris, Rozainanee Mohd Zain, Seanantha S. Baros-Steyl, Andrew J.M. Nel, Muneerah Smith, Houari Abdesselem, Ti-Myen Tan, Raja Nurashirin Raja Mamat, Jonathan M. Blackburn
Publikováno v:
Viruses
Volume 13
Issue 5
Viruses, Vol 13, Iss 786, p 786 (2021)
Volume 13
Issue 5
Viruses, Vol 13, Iss 786, p 786 (2021)
The COVID-19 pandemic has affected all individuals across the globe in some way. Despite large numbers of reported seroprevalence studies, there remains a limited understanding of how the magnitude and epitope utilization of the humoral immune respon
Autor:
Andrew J.M. Nel, Nur Diana Anuar, Kavithambigai Ellan, Teh Norleila Abdul Rahman, Jonathan M. Blackburn, Nur Izwani Shaiful Bahrin, Noorul Hidayah Badri, Rozainanee Mohd Zain, Arif Anwar, Nurul Shielawati Mohamed Rosli, Ti-Myen Tan, Muneerah Smith
Following the COVID-19 pandemic outbreak in late 2019, a large number of antibody tests were developed for use in seroprevalence studies aimed at determining the extent of current or previous SARS-CoV-2 virus infections in a given population. The vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dbe781336b6ebb4aa3d34559f7866a7
https://doi.org/10.1101/2020.09.25.20201269
https://doi.org/10.1101/2020.09.25.20201269
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-10 (2020)
BackgroundNon-Hodgkin lymphoma is of high prevalence among HIV-infected people. In particular, the incidence of HIV-associated Burkitt lymphoma (BL) remains high despite the advent of Highly Active Anti-Retroviral Therapy. Recent evidence shows that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9919042229d635eb82eaf383f744265b
https://hdl.handle.net/11427/33356
https://hdl.handle.net/11427/33356
Autor:
Alexander D. Giddey, Jonathan M. Blackburn, Kehilwe C. Nakedi, Shaun Garnett, Nelson C. Soares, Mousumi Banerjee, Andrew J.M. Nel, Bridget Calder
Publikováno v:
Molecular & Cellular Proteomics : MCP
Mycobacterial Ser/Thr kinases play a critical role in bacterial physiology and pathogenesis. Linking kinases to the substrates they phosphorylate in vivo, thereby elucidating their exact functions, is still a challenge. The aim of this work was to as
Autor:
Jonathan M. Blackburn, Andrew J.M. Nel, Jerome M. Wendoh, Shaun Garnett, Suereta Fortuin, Nicola Mulder, David L. Tabb, Matthys G Potgieter
Metagenome-driven microbiome research is providing important new insights in fields as diverse as the pathogenesis of human disease, the metabolic interactions of complex microbial ecosystems involved in agriculture, and climate change. However, poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37eb7f02fbfaf3b6a8ec0eec3b28946
https://doi.org/10.1101/605550
https://doi.org/10.1101/605550
Publikováno v:
MethodsX, Vol 8, Iss, Pp 101277-(2021)
The Escherichia coli proteome is the most extensively characterized and studied of all prokaryotic proteomes. Despite this, large scale bacterial proteomics experiments performed on E. coli cells grown in liquid cultures have failed to identify key v
Publikováno v:
Journal of Proteomics. 228:103929
Most bacterial proteomic studies done to date utilise bacterial cells harvested from liquid culture media. However, it is widely accepted that many important determinants associated with virulence and host cell adhesion are exclusively expressed duri
Autor:
Jonathan M. Blackburn, Alexander D. Giddey, Andrew J.M. Nel, Nelson C. Soares, Clemens Hermann
Publikováno v:
Journal of proteomics. 191
Understanding the cell wall of mycobacteria is crucial for improving drug design or identifying new antigens suitable to vaccination. Yet this remains problematic due to the complexity of the cell wall composition. In this study, we successfully deve