Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Andrew J. Yates"'
Autor:
Tea Babushku, Markus Lechner, Stefanie Ehrenberg, Ursula Rambold, Marc Schmidt-Supprian, Andrew J. Yates, Sanket Rane, Ursula Zimber-Strobl, Lothar J. Strobl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Sustained Notch2 signals induce trans-differentiation of Follicular B (FoB) cells into Marginal Zone B (MZB) cells in mice, but the physiology underlying this differentiation pathway is still elusive. Here, we demonstrate that most B cells r
Externí odkaz:
https://doaj.org/article/6e11745d8d724719a32b1e692199e761
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Heat waves and droughts increase air pollution from power plants in California, which disproportionately damages counties with a majority of people of color. Droughts cause chronic increases in pollution damages. Heat waves are responsible for the da
Externí odkaz:
https://doaj.org/article/c4b0959ab62043b49dc95eb736cb0faf
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The dynamics of cell populations are frequently studied in vivo using pulse-chase DNA labeling techniques. When combined with mathematical models, the kinetic of label uptake and loss within a population of interest then allows one to estimate rates
Externí odkaz:
https://doaj.org/article/aac52fca7da34e0b83932c702b277971
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative procedure for a large number of diseases. However, the greatest barriers to the success of allo-HCT are relapse and graft-versus-host-disease (GVHD). Many stu
Externí odkaz:
https://doaj.org/article/d189775a3d294f46bb035df567f29fdd
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108376- (2020)
Summary: Follicular mature (FM) and germinal center (GC) B cells underpin humoral immunity, but the dynamics of their generation and maintenance are not clearly defined. Here, we exploited a fate-mapping system in mice that tracks B cells as they dev
Externí odkaz:
https://doaj.org/article/ec56e120c6a942dda905ec078bac470e
Publikováno v:
Atmosphere, Vol 12, Iss 8, p 951 (2021)
The COVID-19 pandemic resulted in stay-at-home policies and other social distancing behaviors in the United States in spring of 2020. This paper examines the impact that these actions had on emissions and expected health effects through reduced perso
Externí odkaz:
https://doaj.org/article/9c9961193aba44b49793d4a14dd9eda0
Autor:
Alan J. Hayes, Sanket Rane, Hannah E. Scales, Gavin R. Meehan, Robert A. Benson, Asher Maroof, Juliane Schroeder, Michio Tomura, Neil Gozzard, Andrew J. Yates, Paul Garside, James M. Brewer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Initiation of adaptive immunity involves distinct migratory cell populations coming together in a highly dynamic and spatially organized process. However, we lack a detailed spatiotemporal map of these events due to our inability to track the fate of
Externí odkaz:
https://doaj.org/article/990e096a122f42f8ab6e7b00751d7cba
Autor:
Rita Rb-Silva, Claudia Nobrega, Cecilia Azevedo, Emilia Athayde, João Canto-Gomes, Ivo Ferreira, Rémi Cheynier, Andrew J. Yates, Ana Horta, Margarida Correia-Neves
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Poor immunological responders (PIR) are HIV-infected patients with virologic suppression upon antiretroviral therapy (ART) but persistently low CD4+ T cell counts. Early identification of PIR is important given their higher morbimortality compared to
Externí odkaz:
https://doaj.org/article/99771c59a68c467e8f8adf2cb3d0fdf4
Publikováno v:
Evolutionary Applications, Vol 6, Iss 2, Pp 365-376 (2013)
Abstract Parasites may alter their behaviour to cope with changes in the within‐host environment. In particular, investment in transmission may alter in response to the availability of parasite resources or host immune responses. However, experimen
Externí odkaz:
https://doaj.org/article/c28a88d11d4e45099b337a38d5b9d6ef
Autor:
Sinead E Morris, Renate Strehlau, Stephanie Shiau, Elaine J Abrams, Caroline T Tiemessen, Louise Kuhn, Andrew J Yates, EPIICAL Consortium and the LEOPARD study team
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010751 (2022)
In 2019 there were 490,000 children under five living with HIV. Understanding the dynamics of HIV suppression and rebound in this age group is crucial to optimizing treatment strategies and increasing the likelihood of infants achieving and sustainin
Externí odkaz:
https://doaj.org/article/03daa5b7e9c64dd8b450ba2a9b2f3919