Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Andrew J. Woo"'
Autor:
Mijeong Kim, Manjot Singh, Bum-Kyu Lee, Moira Hibbs, Kirsty Richardson, Lesley Ellies, Larissa Wintle, Lisa M. Stuart, Jenny Y. Wang, Dominic C. Voon, Pilar Blancafort, Jianlong Wang, Jonghwan Kim, Peter J. Leedman, Andrew J. Woo
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract The MYC proto-oncogene (MYC) is one of the most frequently overexpressed genes in breast cancer that drives cancer stem cell-like traits, resulting in aggressive disease progression and poor prognosis. In this study, we identified zinc finge
Externí odkaz:
https://doaj.org/article/3a2eb9d8862b4252af620303b3ec1a97
Autor:
Dianne J. Beveridge, Kirsty L. Richardson, Michael R. Epis, Rikki A. M. Brown, Lisa M. Stuart, Andrew J. Woo, Peter J. Leedman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract RNA-based therapeutics are emerging as innovative options for cancer treatment, with microRNAs being attractive targets for therapy development. We previously implicated microRNA-642a-5p (miR-642a-5p) as a tumor suppressor in prostate cancer
Externí odkaz:
https://doaj.org/article/cb9118786c3647f78f95a546270cae69
Autor:
Emily Golden, Rabab Rashwan, Eleanor A. Woodward, Agustin Sgro, Edina Wang, Anabel Sorolla, Charlene Waryah, Wan Jun Tie, Elisabet Cuyàs, Magdalena Ratajska, Iwona Kardaś, Piotr Kozlowski, Elizabeth K. M. Johnstone, Heng B. See, Ciara Duffy, Jeremy Parry, Kim A. Lagerborg, Piotr Czapiewski, Javier A. Menendez, Adam Gorczyński, Bartosz Wasag, Kevin D. G. Pfleger, Christina Curtis, Bum-Kyu Lee, Jonghwan Kim, Joseph Cursons, Nathan J. Pavlos, Wojciech Biernat, Mohit Jain, Andrew J. Woo, Andrew Redfern, Pilar Blancafort
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Adipogenesis associated Mth938 Domain Containing gene (AAMDC) is frequently amplified in the IntClus2 subgroup of ER + breast cancer. Here, the authors show that AAMDC drives tumourigenesis through activating PI3K-AKT-mTOR pathway for metabolic repro
Externí odkaz:
https://doaj.org/article/7a78efc95f94434186efe33c5a90c19a
Autor:
Andrew J. Woo, Chelsea-Ann A. Patry, Alireza Ghamari, Gabriela Pregernig, Daniel Yuan, Kangni Zheng, Taylor Piers, Moira Hibbs, Ji Li, Miguel Fidalgo, Jenny Y. Wang, Joo-Hyeon Lee, Peter J. Leedman, Jianlong Wang, Ernest Fraenkel, Alan B. Cantor
Publikováno v:
Blood Advances, Vol 3, Iss 16, Pp 2499-2511 (2019)
Abstract: Erythroid maturation requires the concerted action of a core set of transcription factors. We previously identified the Krüppel-type zinc finger transcription factor Zfp148 (also called ZBP-89) as an interacting partner of the master eryth
Externí odkaz:
https://doaj.org/article/a4a01af35491446d8737b36cfb40774b
Autor:
Estrella Gonzales-Aloy, Patrick Connerty, Basit Salik, Bing Liu, Andrew J. Woo, Michelle Haber, Murray D. Norris, Jianlong Wang, Jenny Y. Wang
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
Externí odkaz:
https://doaj.org/article/436963bc0781433d9f72fe5803c06bc1
Autor:
Andrew J. Woo, Peter J. Leedman, Michael R. Epis, Lisa M. Stuart, Kirsty L. Richardson, Dianne J. Beveridge, Rikki A. M. Brown
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
RNA-based therapeutics are emerging as innovative options for cancer treatment, with microRNAs being attractive targets for therapy development. We previously implicated microRNA-642a-5p (miR-642a-5p) as a tumor suppressor in prostate cancer (PCa), a
Autor:
Francesca M McGrath, Abbie Francis, Daniel M Fatovich, Stephen PJ Macdonald, Glenn Arendts, Andrew J Woo, Erika Bosio
Publikováno v:
Clinical & Translational Immunology. 11
Mechanisms underlying the anaphylactic reaction in humans are not fully understood. Here, we aimed at improving our understanding of anaphylaxis by investigating gene expression changes.Microarray data set GSE69063 was analysed, describing emergency
Autor:
Glenn Arendts, Andrew J. Woo, Erika Bosio, Francesca Marina McGrath, Stephen P J Macdonald, Daniel M Fatovich, Anthony Bosco, Abbie Francis
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 51(10)
BACKGROUND Anaphylaxis is a severe, potentially life-threatening allergic reaction driven primarily by the activation of mast cells. We still fail to understand factors underlying reaction severity. Furthermore, there is currently no reliable diagnos
Autor:
Kevin D. G. Pfleger, Wan Jun Tie, Joseph Cursons, Bum-Kyu Lee, Piotr Kozlowski, Edina Wang, Rabab Rashwan, Ciara Duffy, Mohit Jain, Magdalena Ratajska, Wojciech Biernat, Pilar Blancafort, Piotr Czapiewski, Anabel Sorolla, Agustin Sgro, Andrew J. Woo, Christina Curtis, Jeremy Parry, Kim A. Lagerborg, Charlene Babra Waryah, Elizabeth K. M. Johnstone, Jonghwan Kim, Bartosz Wasag, Eleanor A. Woodward, Javier A. Menendez, Nathan J. Pavlos, Emily Golden, Andrew Redfern, Iwona Kardaś, Heng B. See, Elisabet Cuyàs, Adam Gorczyński
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Adipogenesis associated Mth938 domain containing (AAMDC) represents an uncharacterized oncogene amplified in aggressive estrogen receptor-positive breast cancers. We uncover that AAMDC regulates the expression of several metabolic enzymes involved in
Autor:
Luca Pinello, Andrew J. Woo, Alan B. Cantor, Stuart H. Orkin, Partha Pratim Das, Marc A. Kerenyi, Lee H. Wong, Pratibha Tripathi, Alireza Ghamari, Yogesh Kumar, Jonghwan Kim, Kimberly Glass, Varun K. Pandey, Guo-Cheng Yuan, Majid Mehravar, Dhaval Hathiwala, Michael J. Bullen
SUMMARY Epigenetic regulators and transcription factors establish distinct regulatory networks for gene regulation to maintain the embryonic stem cells (ESC) state. Although much has been learned regarding individual epigenetic regulators, their comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e677088ab8807eeb75d46f69f62a01d0
https://doi.org/10.1101/2020.08.27.269514
https://doi.org/10.1101/2020.08.27.269514