Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrew J. Whitehouse"'
Autor:
Andrew J. Whitehouse
Publikováno v:
Winged Worlds ISBN: 9781003334767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7d86e704249e55446d30b0b6a498a32
https://doi.org/10.4324/9781003334767-5
https://doi.org/10.4324/9781003334767-5
Autor:
Sitthivut Charoensutthivarakul, Sherine E. Thomas, Amy Curran, Karen P. Brown, Juan M. Belardinelli, Andrew J. Whitehouse, Marta Acebrón-García-de-Eulate, Jaspar Sangan, Subramanian G. Gramani, Mary Jackson, Vitor Mendes, R. Andres Floto, Tom L. Blundell, Anthony G. Coyne, Chris Abell
Publikováno v:
ACS Infectious Diseases. 8:296-309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a26c6af4b6de128bd9f1582c73b377
https://doi.org/10.1021/acsinfecdis.1c00432
https://doi.org/10.1021/acsinfecdis.1c00432
Autor:
Sophie Burbaud, Andrew J. Whitehouse, Ramanuj Lahiri, Jasper Sangen, Sherine E. Thomas, Tom L. Blundell, Pooja Gupta, Helena I. Boshoff, Juan Manuel Belardinelli, Mary Jackson, Sony Malhotra, R. Andres Floto, Karen Brown, M. Daben J. Libardo, Anthony G. Coyne, Vitor Mendes, Chris Abell
Publikováno v:
Nucleic Acids Research
Translational frameshift errors are often deleterious to the synthesis of functional proteins and could therefore be promoted therapeutically to kill bacteria. TrmD (tRNA-(N(1)G37) methyltransferase) is an essential tRNA modification enzyme in bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0499f42b3a6c17233ceb9dfce7e5197
https://doi.org/10.1093/nar/gkaa539
https://doi.org/10.1093/nar/gkaa539
Autor:
Sitthivut, Charoensutthivarakul, Sherine E, Thomas, Amy, Curran, Karen P, Brown, Juan M, Belardinelli, Andrew J, Whitehouse, Marta, Acebrón-García-de-Eulate, Jaspar, Sangan, Subramanian G, Gramani, Mary, Jackson, Vitor, Mendes, R Andres, Floto, Tom L, Blundell, Anthony G, Coyne, Chris, Abell
Publikováno v:
ACS infectious diseases. 8(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f43cb82ca1f3f2fee243188700ff828
https://pubmed.ncbi.nlm.nih.gov/35037462
https://pubmed.ncbi.nlm.nih.gov/35037462
Autor:
M. Daben J. Libardo, Monica Kasbekar, Helena I. Boshoff, Chris Abell, Craig J. Thomas, Clifton E. Barry, Paul Brear, Gerhard Fischer, Anthony G. Coyne, Andrew J. Whitehouse
With the growing worldwide prevalence of antibiotic-resistant strains of tuberculosis (TB), new targets are urgently required for the development of treatments with novel modes of action. Fumarate hydratase (fumarase), a vulnerable component of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2137f8a13f7a26d72652b5607976c34b
Autor:
Andrew J, Whitehouse, M Daben J, Libardo, Monica, Kasbekar, Paul D, Brear, Gerhard, Fischer, Craig J, Thomas, Clifton E, Barry, Helena I M, Boshoff, Anthony G, Coyne, Chris, Abell
Publikováno v:
Journal of medicinal chemistry. 62(23)
With the growing worldwide prevalence of antibiotic-resistant strains of tuberculosis (TB), new targets are urgently required for the development of treatments with novel modes of action. Fumarate hydratase (fumarase), a vulnerable component of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e8aad1da00b12a0e6107be5a5b28f21
https://pubmed.ncbi.nlm.nih.gov/31664826
https://pubmed.ncbi.nlm.nih.gov/31664826
Autor:
Vitor Mendes, Alexander Fanourakis, Andrew J. Whitehouse, Daniel Shiu-Hin Chan, M. Daben J. Libardo, Sherine E. Thomas, Helena I. Boshoff, Karen Brown, Tom L. Blundell, Chris Abell, R. Andres Floto, Anthony G. Coyne
Publikováno v:
Journal of Medicinal Chemistry
Mycobacterium abscessus (Mab) is a rapidly growing species of multidrug-resistant nontuberculous mycobacteria (NTM) that has emerged as a growing threat to individuals with cystic fibrosis, and other pre-existing chronic lung diseases. Mab pulmonary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52186c7af72fee73a2e1c29f1c70c7d2
https://doi.org/10.26434/chemrxiv.8131847.v1
https://doi.org/10.26434/chemrxiv.8131847.v1
Autor:
Sony Malhotra, Helena I. Boshoff, Tom L. Blundell, Ramanuj Lahiri, Pooja Gupta, Anthony G. Coyne, Karen Brown, Vitor Mendes, Mary Jackson, M. Daben J. Libardo, R. Andres Floto, Andrew J. Whitehouse, Chris Abell, Juan Manuel Belardinelli, Sherine E. Thomas
Translational frameshift errors are often deleterious to the synthesis of functional proteins as they lead to the production of truncated or inactive proteins. TrmD (tRNA-(N(1)G37) methyltransferase) is an essential tRNA modification enzyme in bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b866cafe1277b7e1a848da7a0391e3
https://doi.org/10.1101/564013
https://doi.org/10.1101/564013
Publikováno v:
Essays in biochemistry. 61(5)
Fragment-based approaches in chemical biology and drug discovery have been widely adopted worldwide in both academia and industry. Fragment hits tend to interact weakly with their targets, necessitating the use of sensitive biophysical techniques to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8881b744c7ce28079c90a65ddca29b4e
https://pubmed.ncbi.nlm.nih.gov/28986384
https://pubmed.ncbi.nlm.nih.gov/28986384
Autor:
Caleb H. Ing, Charles J. DiMaggio, Eva Malacova, Andrew J. Whitehouse, Mary K. Hegarty, Tianshu Feng, Joanne E. Brady, Britta S. von Ungern-Sternberg, Andrew J. Davidson, Melanie M. Wall, Alastair J. J. Wood, Guohua Li, Lena S. Sun
Publikováno v:
Anesthesiology. 122(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a323c7b7845c4f08e3b85258e28e722e
https://pubmed.ncbi.nlm.nih.gov/25611662
https://pubmed.ncbi.nlm.nih.gov/25611662