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pro vyhledávání: '"Andrew J. Veenis"'
Autor:
Raghav R. Poudyal, Rebecca M. Guth-Metzler, Andrew J. Veenis, Erica A. Frankel, Christine D. Keating, Philip C. Bevilacqua
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Membraneless compartments have been theorized to be prebiotic micro-compartments as they spontaneously encapsulate RNA and proteins. Here, the authors report membraneless compartments can enhance RNA chemistries, affecting template directed RNA polym
Externí odkaz:
https://doaj.org/article/bd95f9acb3e540aebabd151c0ada12ad
Autor:
Andrew J. Veenis, Sharon Hammes-Schiffer, Alexander V. Soudackov, Pengfei Li, Philip C. Bevilacqua
Publikováno v:
J Phys Chem B
Small ribozymes cleave their RNA phosphodiester backbone by catalyzing a transphosphorylation reaction wherein a specific O2′ functions as the nucleophile. While deprotonation of this alcohol through its acidification would increase its nucleophili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a62c1cc12cf40e7ae8d4f5890f9103f
https://europepmc.org/articles/PMC8760728/
https://europepmc.org/articles/PMC8760728/
Autor:
Erica A. Frankel, Christine D. Keating, Rebecca M. Guth-Metzler, Andrew J. Veenis, Philip C. Bevilacqua, Raghav R. Poudyal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Membraneless compartments, such as complex coacervates, have been hypothesized as plausible prebiotic micro-compartments due to their ability to sequester RNA; however, their compatibility with essential RNA World chemistries is unclear. We show that
Autor:
Daniel D. Seith, Aileen Charlotte Button, Philip C. Bevilacqua, Andrew J. Veenis, Jamie L. Bingaman
Publikováno v:
ACS Catal
A number of small, self-cleaving ribozyme classes have been identified including the hammerhead, hairpin, hepatitis delta virus (HDV), Varkud satellite (VS), glmS, twister, hatchet, pistol, and twister sister ribozymes. Within the active sites of the