Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andrew J. Stout"'
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110877- (2024)
Summary: Cultivated meat has the potential to revolutionize food production, but its progress is hindered by fundamental shortcomings of mammalian cells with respect to industrial-scale bioprocesses. Here, we discuss the essential role of cell line e
Externí odkaz:
https://doaj.org/article/91a3b1b43bd540739d2317a4a5fdac26
Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production
Autor:
Andrew J. Stout, Xiaoli Zhang, Sophia M. Letcher, Miriam L. Rittenberg, Michelle Shub, Kristin M. Chai, Maya Kaul, David L. Kaplan
Publikováno v:
Cell Reports Sustainability, Vol 1, Iss 1, Pp 100009- (2024)
Summary: Cultivated meat (also known as cultured meat) is a promising technology that faces substantial cost barriers, which are currently driven by the price of media components. Particularly, growth factors such as fibroblast growth factor 2 (FGF2)
Externí odkaz:
https://doaj.org/article/7db4b25dd4fd4cd982ba5c70b1f80d7f
Autor:
Andrew J. Stout, Addison B. Mirliani, Miriam L. Rittenberg, Michelle Shub, Eugene C. White, John S. K. Yuen, David L. Kaplan
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
A substitution of FBS in culturing of bovine satellite cells for the purpose of culturing meat is presented, addressing both basal media and growth factors in relation to proliferating and differentiating cells.
Externí odkaz:
https://doaj.org/article/53acdfeeb8df45cba87efdafcacebbec
Autor:
Andrew J. Stout, Miles J. Arnett, Kristin Chai, Tina Guo, Lishu Liao, Addison B. Mirliani, Miriam L. Rittenberg, Michelle Shub, Eugene C. White, John S. K. Yuen, Xiaoli Zhang, David L. Kaplan
Publikováno v:
ACS Synthetic Biology. 12:1567-1573
For cultured meat to succeed at scale, muscle cells from food-relevant species must be expandedin vitroin a rapid and reliable manner to produce millions of metric tons of biomass annually. Toward this goal, genetically immortalized cells offer subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e543715666ffaaa69d3f2d386a5340c
https://doi.org/10.1021/acssynbio.3c00216
https://doi.org/10.1021/acssynbio.3c00216
Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production
Autor:
Andrew J. Stout, Xiaoli Zhang, Sophia M. Letcher, Miriam L. Rittenberg, Michelle Shub, Kristin M. Chai, Maya Kaul, David L. Kaplan
Publikováno v:
bioRxiv
Cultured meat is a promising technology that faces substantial cost barriers which are currently driven largely by the price of media components. Growth factors such as fibroblast growth factor 2 (FGF2) drive the cost of serum-free media for relevant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a79dfcf4870d4cb061d1e44cbd15f4a
https://europepmc.org/articles/PMC10153192/
https://europepmc.org/articles/PMC10153192/
Autor:
Andrew J. Stout, Miriam L. Rittenberg, Michelle Shub, Michael K. Saad, Addison B. Mirliani, David L. Kaplan
The development of cost-effective serum-free media is essential for the economic viability of cultured meat. A key challenge facing this goal is high-cost recombinant albumin that is necessary in some available serum-free media formulations. As such,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f44b94be10eb499a23692fd8ab3fe0
https://doi.org/10.1101/2022.09.02.506409
https://doi.org/10.1101/2022.09.02.506409
Autor:
Andrew J. Stout, Miriam L. Rittenberg, Michelle Shub, Michael K. Saad, Addison B. Mirliani, James Dolgin, David L. Kaplan
Publikováno v:
Biomaterials. 296:122092
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0a6e9ce7f0d06ff788b664b64cc7961
https://doi.org/10.1016/j.biomaterials.2023.122092
https://doi.org/10.1016/j.biomaterials.2023.122092
Autor:
Erin L. Soule-Albridge, Julian M. Cohen, David L. Kaplan, Andrew J. Stout, Addison B. Mirliani
Publikováno v:
Metab Eng
Metabolic engineering of mammalian cells has to-date focused primarily on biopharmaceutical protein production or the manipulation of native metabolic processes towards therapeutic aims. However, significant potential exists for expanding these techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c226fae92af28eb59b4d76e74581222
https://doi.org/10.1016/j.ymben.2020.07.011
https://doi.org/10.1016/j.ymben.2020.07.011
Autor:
Ning Xiang, Ya Yao, John S.K. Yuen, Andrew J. Stout, Colin Fennelly, Ryan Sylvia, Aletta Schnitzler, Shou Wong, David L. Kaplan
Publikováno v:
Biomaterials. 287
Biomaterial scaffolds are critical components in cultivated meat production for enabling cell adhesion, proliferation, differentiation and orientation. Currently, there is limited information on the fabrication of edible/biodegradable scaffolds for c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42dc4c80bc1aa5883e3d30c77cd4e669
https://pubmed.ncbi.nlm.nih.gov/35839585
https://pubmed.ncbi.nlm.nih.gov/35839585
Autor:
Sophia K. Theodossiou, Hailey DiCindio, Michael K. Saad, Amy C. Rowat, N. Stephanie Kawecki, Brigid M. Barrick, David L. Kaplan, Sophia Letcher, Julian Cohen, Jaymie A. Pietropinto, John S.K. Yuen, Sabrina W. Zhang, Andrew J. Stout, Natalie R. Rubio
Publikováno v:
Biomaterials
With rising global demand for food proteins and significant environmental impact associated with conventional animal agriculture, it is important to develop sustainable alternatives to supplement existing meat production. Since fat is an important co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64c313565a18b433f431abe5de60966
https://europepmc.org/articles/PMC8725203/
https://europepmc.org/articles/PMC8725203/