Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Andrew J. Spracklen"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3555-3565 (2019)
Prostaglandins (PGs) are lipid signaling molecules with numerous physiologic functions, including pain/inflammation, fertility, and cancer. PGs are produced downstream of cyclooxygenase (COX) enzymes, the targets of non-steroidal anti-inflammatory dr
Externí odkaz:
https://doaj.org/article/77b2c94c8a6748f69c766b2ef2b6446e
Autor:
Alison N. Bonner, Andrew J. Spracklen, Rodrigo Fernandez-Gonzalez, Alexandru Florea, Mark Peifer, Emma M. Thornton-Kolbe, Peter J. Compton
Publikováno v:
Molecular Biology of the Cell. 30:2399-2421
Small Src homology domain 2 (SH2) and 3 (SH3) adapter proteins regulate cell fate and behavior by mediating interactions between cell surface receptors and downstream signaling effectors in many signal transduction pathways. The CT10 regulator of kin
Autor:
Christopher M. Groen, Tina L. Tootle, Anna K. Allen, Andrew J. Spracklen, Daniel Kelpsch, Darren S. Hoffmann
Publikováno v:
Journal of College Science Teaching.
Publikováno v:
Developmental Biology. 393:209-226
Dynamic remodeling of the actin cytoskeleton is required for both development and tissue homeostasis. While fixed image analysis has provided significant insight into such events, a complete understanding of cytoskeletal dynamics requires live imagin
Publikováno v:
Molecular Biology of the Cell
Tight regulation of actin remodeling is essential for development, and misregulation results in disease. Cytoskeletal dynamics are regulated by prostaglandins (PGs)—lipid signals. PGs temporally regulate actin remodeling during Drosophila oogenesis
Autor:
Colleen G. Bilancia, Stephanie H. Nowotarski, S. Colby Allred, Andrew J. Spracklen, Mark Peifer, Benjamin J. Ritchie, Edward M. Rogers, Kaelyn D. Sumigray, Kristina N. Schaefer
Publikováno v:
Molecular Biology of the Cell
The importance of Abl kinase activity, the F-actin–binding site, and scaffolding ability in Abl’s many cell biological roles during Drosophila morphogenesis is examined. Abl is a robust multidomain scaffold with different protein motifs and activ
Autor:
Mark Peifer, Andrew J. Spracklen
Publikováno v:
Developmental cell. 35(6)
The propagation of force in epithelial tissues requires that the contractile cytoskeletal machinery be stably connected between cells through E-cadherin-containing adherens junctions. In many epithelial tissues the cells’ contractile network is pos
Autor:
Andrew J. Spracklen, Tina L. Tootle
Publikováno v:
Bioactive Lipid Mediators ISBN: 9784431556688
Prostaglandin (PG) synthesis and signaling are conserved in Drosophila melanogaster. PGs are produced downstream of cyclooxygenase or COX enzymes, the targets of nonsteroidal anti-inflammatory drugs. Almost 20 years ago, biochemical studies suggested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25926d1d1a8248c21050990765b12e56
https://doi.org/10.1007/978-4-431-55669-5_13
https://doi.org/10.1007/978-4-431-55669-5_13
Autor:
Andrew J, Spracklen, Tina L, Tootle
Publikováno v:
Journal of visualized experiments : JoVE. (82)
Drosophila oogenesis or follicle development has been widely used to advance the understanding of complex developmental and cell biologic processes. This methods paper describes how to isolate mid-to-late stage follicles (Stage 10B-14) and utilize th