Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew J. Sonderfan"'
Autor:
Yuan Liu, Josephine Ye, Luisa Shin Ogawa, Takayo Inoue, Qin Huang, John Chu, Richard C Bates, Weiwen Ying, Andrew J Sonderfan, Patricia E Rao, Dan Zhou
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127361 (2015)
Systemic lupus erythematosus (SLE) is a complex, systemic autoimmune disease with a diverse range of immunological and clinical manifestations. The introduction of broad spectrum immunosuppressive therapies and better management of acute disease exac
Externí odkaz:
https://doaj.org/article/9d2de1569a5d4281b33a286a3638a459
Publikováno v:
Archives of Biochemistry and Biophysics. 251:188-197
The aim of the present study was to investigate whether the mechanism by which pregnenolone-16α-carbonitrile (PCN) protects rats from digitoxin toxicity was dependent on the induction of liver microsomal cytochrome P -450 p and/or the UDP-glucuronos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e9004dbe5740187a1281fd7ba762b7
https://doi.org/10.1016/0003-9861(86)90065-2
https://doi.org/10.1016/0003-9861(86)90065-2
Publikováno v:
Biochemical Pharmacology. 36:3859-3866
Treatment of rats with pregnenolone-16 alpha-carbonitrile (PCN) markedly induces rat liver microsomal cytochrome P-450p and UDP-GT-dt1, a glucuronosyltransferase active towards the digitoxin metabolite, digitoxigenin monodigitoxoside. The present stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ad96277957171f1681c7632fb5544b
https://doi.org/10.1016/0006-2952(87)90450-3
https://doi.org/10.1016/0006-2952(87)90450-3
Publikováno v:
Archives of Biochemistry and Biophysics. 255:316-328
The aim of the present study was to examine a recent proposal that inhibitory isozyme:isozyme interactions explain why membrane-bound isozymes of rat liver microsomal cytochrome P-450 exert only a fraction of the catalytic activity they express when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed213cb68f8d984b2f9b56b5f7dcc9c
https://doi.org/10.1016/0003-9861(87)90399-7
https://doi.org/10.1016/0003-9861(87)90399-7
Publikováno v:
Endocrinology. 125:857-866
Previous studies have shown that several forms of cytochrome P-450 present in rat liver microsomes oxidize testosterone with a high degree of regio- and stereospecificity. The aim of this study was to characterize the pathways of testosterone oxidati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd904a539de0beaf3fc4837c0584d17
https://doi.org/10.1210/endo-125-2-857
https://doi.org/10.1210/endo-125-2-857
Autor:
Andrew J. Sonderfan, Andrew Parkinson
Publikováno v:
Archives of Biochemistry and Biophysics. 265:208-218
It has been shown previously that liver microsomal steroid 5α-reductase activity increases with age in female but not male rats, which coincides with a female-specific, age-dependent decline in the cytochrome P-450-dependent oxidation of testosteron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393275b1fb31eedb4c40319549be2177
https://doi.org/10.1016/0003-9861(88)90386-4
https://doi.org/10.1016/0003-9861(88)90386-4
Autor:
Andrew Parkinson, David R. Dutton, Michael P. Arlotto, Andrew J. Sonderfan, Susan K. McMillen
Publikováno v:
Archives of biochemistry and biophysics. 255(1)
The pathways of testosterone oxidation catalyzed by purified and membrane-bound forms of rat liver microsomal cytochrome P-450 were examined with an HPLC system capable of resolving 14 potential hydroxylated metabolites of testosterone and androstene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e653280a99a53795e3cc98d8d881225
https://pubmed.ncbi.nlm.nih.gov/3592665
https://pubmed.ncbi.nlm.nih.gov/3592665
Publikováno v:
Synta Pharmaceuticals Corp. MarketLine Company Profile. 11/3/2015, p1-15. 15p.
Publikováno v:
Synta Pharmaceuticals Corp. MarketLine Company Profile. 11/19/2014, p1-15. 16p.
Autor:
Bourne, Nigel, Bernstein, David I., Ireland, James, Sonderfan, Andrew J., Profy, Albert T., Stanberry, Lawrence R.
Publikováno v:
Journal of Infectious Diseases; 7/1/99, Vol. 180 Issue 1, p203-205, 3p