Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Andrew J. Skildum"'
Autor:
Donald W. Kundel, Katherine D. Kundel, Ronald R. Regal, Amy L. Greene, Olga Zhdankin, Andrew J. Skildum, Teresa A. Rose-Hellekant
Supplementary Figure 1 from Short-term Prophylactic Tamoxifen Reduces the Incidence of Antiestrogen-Resistant/Estrogen Receptor–Positive/Progesterone Receptor–Negative Mammary Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7436a5f38f794e01df931c8970ac1159
https://doi.org/10.1158/1940-6207.22523154
https://doi.org/10.1158/1940-6207.22523154
Publikováno v:
Cell Cycle
Doxorubicin induces both DNA damage and metabolic interference. How these effects interact to modulate cellular toxicity is not completely understood but important given the widespread use of doxorubicin in cancer treatment. This study tests the hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82abc62712e3f71c454eb926c60da3b3
https://pubmed.ncbi.nlm.nih.gov/33978554
https://pubmed.ncbi.nlm.nih.gov/33978554
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1256 (2007)
Estrogens are required for the proliferation of hormone dependent breast cancer cells, making estrogen receptor (ER) positive tumors amenable to endocrine therapies such as antiestrogens. However, resistance to these agents remains a significant caus
Externí odkaz:
https://doaj.org/article/0b011457b3c24e748cb539c995e0ab5b
Autor:
Douglas A. Hicks, Kevin W. Diebel, Lynne T. Bemis, Evan Odean, Juan E. Abrahante, Kun Zhou, Jon M Holy, Brent Schotl, Monique A. Spillman, Andrew J Skildum
Publikováno v:
Oncotarget
// Kun Zhou 1 , Kevin W. Diebel 1 , Jon Holy 1 , Andrew Skildum 1 , Evan Odean 1 , Douglas A. Hicks 2 , Brent Schotl 1 , Juan E. Abrahante 3 , Monique A. Spillman 4 and Lynne T. Bemis 1 1 Department of Biomedical Sciences, University of Minnesota, Du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe950cfe1d188188d46b1a3c1515658
http://europepmc.org/articles/PMC5707028
http://europepmc.org/articles/PMC5707028
Aspartate facilitates mitochondrial function, growth arrest and survival during doxorubicin exposure
Publikováno v:
Cell Cycle
Genomic screens of doxorubicin toxicity in S. cerevisiae have identified numerous mutants in amino acid and carbon metabolism which express increased doxorubicin sensitivity. This work examines the effect of amino acid metabolism on doxorubicin toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e9e96fe2a44e8244a754c19cf6690f
http://europepmc.org/articles/PMC4825578
http://europepmc.org/articles/PMC4825578
Autor:
Paulo J. Oliveira, Cheryl Zehowski, Kendall B. Wallace, Andrew J Skildum, Kendra K. S. Nordgren, Cláudia M. Deus
Publikováno v:
Toxicology. 334:1-11
Doxorubicin (DOX) is currently used in cancer chemotherapy, however, its use often results in adverse effects highlighted by the development of cardiomyopathy and ultimately heart failure. Interestingly, DOX cardiotoxicity is decreased by resveratrol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fdc5b736139ef4e9e1394453780f309
https://doi.org/10.1016/j.tox.2015.05.001
https://doi.org/10.1016/j.tox.2015.05.001
Autor:
Andrew J Skildum, Kenneth J. Dornfeld
Publikováno v:
Mitochondrial Biology and Experimental Therapeutics ISBN: 9783319733432
Cancer cells are characterized by altered metabolism and uncontrolled proliferation. It is not surprising that mitochondria, which serve important roles in fuel oxidation (catabolism) and synthesizing biosynthetic precursors (anabolism), are altered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd2efb183978d4ad43eb1d11941c51ab
https://doi.org/10.1007/978-3-319-73344-9_9
https://doi.org/10.1007/978-3-319-73344-9_9
Autor:
Amy J. Prunuske, Andrew J Skildum
Publikováno v:
Medical Science Educator. 24:103-109
Many medical schools have adopted competency-based education where educators identify the necessary knowledge and skills expected of their students and design activities and assessments to help determine whether students have achieve these competenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eea2094aea139536b25b35ff0a458d24
https://doi.org/10.1007/s40670-014-0010-9
https://doi.org/10.1007/s40670-014-0010-9
Publikováno v:
Medical Education
Medical Education Online, Vol 22, Iss 1 (2017)
Medical Education Online, Vol 22, Iss 1 (2017)
Background and objectives: A four-week interdisciplinary pre-matriculation program for Native American and rural medical students was created and its impact on students’ transition to medical school was assessed. The program extends the goals of ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad72d433ddfc22baa9ebf83eeaffdcd
http://europepmc.org/articles/PMC5328374
http://europepmc.org/articles/PMC5328374
Autor:
Ming Qiu, Carol A. Lange, Andrea R. Daniel, Emily J. Faivre, Julie H. Ostrander, Andrew J Skildum
Publikováno v:
Steroids. 72:188-201
Progesterone receptor (PR) action is linked to epidermal growth factor (EGF) initiated signaling pathways at multiple levels; mitogen-activated protein kinases (MAPKs) are key mediators of this important cross-talk. Herein, we probed the effects of E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c628f0a51845999716de74d0119ce336
https://doi.org/10.1016/j.steroids.2006.11.009
https://doi.org/10.1016/j.steroids.2006.11.009