Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrew J. Rivnak"'
Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans.
Autor:
Henrik Zetterberg, Erik Mörtberg, Linan Song, Lei Chang, Gail K Provuncher, Purvish P Patel, Evan Ferrell, David R Fournier, Cheuk W Kan, Todd G Campbell, Ray Meyer, Andrew J Rivnak, Brian A Pink, Kaitlin A Minnehan, Tomasz Piech, David M Rissin, David C Duffy, Sten Rubertsson, David H Wilson, Kaj Blennow
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28263 (2011)
Amyloid β (Aβ) peptides are proteolytic products from amyloid precursor protein (APP) and are thought to play a role in Alzheimer disease (AD) pathogenesis. While much is known about molecular mechanisms underlying cerebral Aβ accumulation in fami
Externí odkaz:
https://doaj.org/article/bd279e68e5df447f8caafa35e86ed2e2
Autor:
Cheuk W. Kan, David C. Duffy, David M. Rissin, Todd G. Campbell, Derek R. DuPont, Andrew J. Rivnak, Carlos Cabrera, David Fournier, Sean Sullivan, Melissa Gardel, Brian A. Pink, Matthew W. Fishburn, Tomasz Piech, Linan Song
Publikováno v:
Journal of Immunological Methods. 424:20-27
We report a system and assay for performing fully-automated measurement of 6 proteins simultaneously with single molecule sensitivity. The system combines handling of samples, reagents, and consumables, with a module for imaging single molecule array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584185c8c2ca6739c7ccbcfa74dad842
https://doi.org/10.1016/j.jim.2015.04.017
https://doi.org/10.1016/j.jim.2015.04.017
Autor:
David H. Wilson, Purvish P. Patel, Linan Song, Andrew J. Rivnak, Brian A. Pink, Mary A. Till, Lei Chang, Cheuk W. Kan, David C. Duffy, Gail K. Provuncher, David Hanlon, Kaitlin A. Minnehan, David Fournier, William A. Faubion, Evan P. Ferrell, Todd G. Campbell
Publikováno v:
Journal of Immunological Methods. 372:177-186
The quantitative measurement of inflammatory cytokines in blood has been limited by insufficient sensitivity of conventional immunoassays. This limitation has prevented the widespread clinical monitoring of cytokine concentrations in chronic inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50154c2f5380203bc377483f10542b7
https://doi.org/10.1016/j.jim.2011.07.015
https://doi.org/10.1016/j.jim.2011.07.015
Autor:
Cheuk W. Kan, Brian A. Pink, David H. Wilson, Purvish P. Patel, David C. Duffy, David M. Rissin, Linan Song, David Fournier, Evan P. Ferrell, Andrew J. Rivnak, Tomasz Piech, Gail K. Provuncher, Stuart C. Howes, Lei Chang, Kaitlin A. Minnehan, Todd G. Campbell
Publikováno v:
Analytical Chemistry. 83:2279-2285
We report a method for combining the detection of single molecules (digital) and an ensemble of molecules (analog) that is capable of detecting enzyme label from 10(-19) M to 10(-13) M, for use in high sensitivity enzyme-linked immunosorbent assays (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3779dfc2a308af6b419c2748130c308c
https://doi.org/10.1021/ac103161b
https://doi.org/10.1021/ac103161b
Autor:
Jeffrey Randall, Cheuk W. Kan, Andrew J. Rivnak, Tomasz Piech, Purvish P. Patel, David C. Duffy, David R. Walt, David Fournier, Gail K. Provuncher, Stuart C. Howes, Lei Chang, David M. Rissin, Linan Song, Todd G. Campbell, Evan P. Ferrell
Publikováno v:
Nature biotechnology
The ability to detect single protein molecules in blood could accelerate the discovery and use of more sensitive diagnostic biomarkers. To detect low-abundance proteins in blood, we captured them on microscopic beads decorated with specific antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6867354f00d0c7695315b37a4dcef6
https://doi.org/10.1038/nbt.1641
https://doi.org/10.1038/nbt.1641
Autor:
Andrew J. Rivnak, Todd G. Campbell, Evan P. Ferrell, Matthias Mösl, Tomasz Piech, David Fournier, Hans-Peter Niederberger, Andrej Peterça, David H. Wilson, Cheuk W. Kan, David M. Rissin, Kaitlin A. Minnehan, David C. Duffy, Purvish P. Patel, Raymond E. Meyer, Lei Chang
Publikováno v:
Lab on a chip. 12(5)
We report a method for isolating individual paramagnetic beads in arrays of femtolitre-sized wells and detecting single enzyme-labeled proteins on these beads using sequential fluid flows in microfabricated polymer array assemblies. Arrays of femtoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5d37aa707d05c2307c4d9896c38b31
https://pubmed.ncbi.nlm.nih.gov/22179487
https://pubmed.ncbi.nlm.nih.gov/22179487
Autor:
David C. Duffy, Raymond E. Meyer, Andrew J. Rivnak, David M. Rissin, Tomasz Piech, Qichao Shao, David Fournier, Linan Song, Matthew W. Fishburn, Evan P. Ferrell, Todd G. Campbell, Cheuk W. Kan
Publikováno v:
Lab on a Chip. 13:2902
We have developed a method that enables the multiplexed detection of proteins based on counting single molecules. Paramagnetic beads were labeled with fluorescent dyes to create optically distinct subpopulations of beads, and antibodies to specific p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0442e3732aabb60d4c4a48ec2f12d9be
https://doi.org/10.1039/c3lc50416f
https://doi.org/10.1039/c3lc50416f
Autor:
Kaj Blennow, Brian A. Pink, Erik Mörtberg, David Fournier, Sten Rubertsson, Gail K. Provuncher, Lei Chang, Ray E. Meyer, Andrew J. Rivnak, David H. Wilson, Purvish P. Patel, Evan P. Ferrell, David M. Rissin, Henrik Zetterberg, Linan Song, Todd G. Campbell, Kaitlin A. Minnehan, Cheuk W. Kan, David C. Duffy, Tomasz Piech
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28263 (2011)
PLoS ONE
PLoS ONE
Amyloid β (Aβ) peptides are proteolytic products from amyloid precursor protein (APP) and are thought to play a role in Alzheimer disease (AD) pathogenesis. While much is known about molecular mechanisms underlying cerebral Aβ accumulation in fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1b36190d6adda85de62526025506c4
https://doi.org/10.1371/journal.pone.0028263
https://doi.org/10.1371/journal.pone.0028263
Autor:
David M. Rissin, Tomasz Piech, Jeff Randall, David M. Wilson, David R. Walt, Cheuk W. Kan, Andrew J. Rivnak, Stuart C. Howes, Linan Song, Gail K. Provuncher, Purvish P. Patel, David C. Duffy, David Fournier, Evan P. Ferrell, Todd G. Campbell
Publikováno v:
Clinical Cancer Research. 16:B14-B14
Purpose: Develop a method for measuring prostate specific antigen (PSA) in the serum of patients who have undergone radical prostatectomy (RP). The method is based on Single Molecule Array (SiMoATM) technology in which individual molecules of analyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cdedc88b0ec52ae45aecce1793e24af
https://doi.org/10.1158/diag-10-b14
https://doi.org/10.1158/diag-10-b14