Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Andrew J. Reason"'
Autor:
Andras G. Lacko, Andrew J. Reason, Colin Nuckolls, Bhalchandra J. Kudchodkar, Maya P. Nair, Geetha Sundarrajan, P. Haydn Pritchard, Howard R. Morris, Anne Dell
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 4, Pp 807-820 (1998)
The major N-linked carbohydrate structures were determined for recombinant human plasma lecithin:cholesterol acyltransferase (LCAT). The analysis of the structure of oligosaccharides by fast atom bombardment mass spectrometry (FAB-MS) and linkage ana
Externí odkaz:
https://doaj.org/article/849096fa55c649258b347e7472ca726e
Autor:
A. Tony Etienne, Adam O. Whelan, Richard L. Easton, Stephen L. l. Michell, Douglas B. Young, Stuart M. Haslam, R. Glyn Hewinson, Anne Dell, Paul R. Wheeler, Maria Panico, Andrew J. Reason, Jean-Louis Herrmann, Howard R. Morris
Publikováno v:
Journal of Biological Chemistry. 278:16423-16432
Mycobacterium tuberculosis and Mycobacterium bovis, the causative agents of human and bovine tuberculosis, have been reported to express a range of surface and secreted glycoproteins, although only one of these has been subjected to detailed structur
Autor:
Howard R. Morris, Vincent Vidal, Andrew J. Reason, Thanai Paxton, A. Dell, Maria Panico, Dominic P. Kwiatkowski, Ian G. Scragg
Publikováno v:
Journal of Biological Chemistry. 275:937-941
Louse-borne relapsing fever, caused by Borrelia recurrentis, provides one of the best documented examples of the causative role of tumor necrosis factor (TNF) in the pathology of severe infection in humans. We have identified the principal TNF-induci
Autor:
Luc-Alain Savoy, Jean-Claude Jaton, Andrew J. Reason, Séverine Frutiger-Hughes, Graham J. Hughes
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1434:86-93
Human secretory component has seven putative sites for N -linked glycosylation. From tryptic and Glu-C digests we have isolated peptides encompassing asparagines 65, 72, 117, 168, 403, 451 and 481. Analysis by on line HPLC-electrospray mass spectrome
Autor:
William Harnett, Andrew J. Reason, Howard R. Morris, Stuart M. Haslam, Katrina M. Houston, Anne Dell
Publikováno v:
Journal of Biological Chemistry. 274:20953-20960
N-Type glycans containing phosphorylcholine (PC-glycans), unusual structures found in the important human pathogens filarial nematodes, represent a novel target for chemotherapy. Previous work in our laboratories produced compositional information on
Autor:
Andrew J. Reason, Stuart M. Haslam, O. S. Chizhov, Howard R. Morris, Anatolii I. Usov, Anne Dell, Roy A. McDowell, Alexander O. Chizhov
Publikováno v:
Carbohydrate Research. 310:203-210
MALDI and FAB mass spectrometry were applied to eight samples of laminarans from different algal species. The existence of both M-chains (mannitol-containing) and G-chains (mannitol-free) was confirmed for six of them, as well as the absence of M-cha
Autor:
Yang Kevin Xiang, Kori Stella, Laurel Thomas, Gseping Liu, François Jean, Andrew J. Reason, Gary Thomas
Publikováno v:
Proceedings of the National Academy of Sciences. 95:7293-7298
The important role of furin in the proteolytic activation of many pathogenic molecules has made this endoprotease a target for the development of potent and selective antiproteolytic agents. Here, we demonstrate the utility of the protein-based inhib
Publikováno v:
Molecular and Biochemical Parasitology. 93:143-147
Autor:
P. Haydn Pritchard, Anne Dell, Andras G. Lacko, Geetha Sundarrajan, Bhalchandra J. Kudchodkar, Howard R. Morris, Colin Nuckolls, Andrew J. Reason, Maya Nair
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 4, Pp 807-820 (1998)
The major N-linked carbohydrate structures were determined for recombinant human plasma lecithin:cholesterol acyltransferase (LCAT). The analysis of the structure of oligosaccharides by fast atom bombardment mass spectrometry (FAB-MS) and linkage ana
Autor:
Lauri A. Ellis, Anne Dell, Florencio M. Ubeira, Judith A. Appleton, Andrew J. Reason, Howard R. Morris, R. Iglesias
Publikováno v:
Glycobiology. 4:585-592
We have investigated the role of glycans on Trichinella spiralis antigens in recognition by rat monoclonal antibodies (mAbs) which protect rat pups against challenge with the parasite. In pups born to infected dams or pups passively immunized with mA