Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Andrew J. Payne"'
Autor:
Christina A. Nelson, James N. Brundage, Benjamin M. Williams, Jared K. Baldridge, Alyssa L. Stockard, Charlton H. Bassett, Brandon J. Burger, Bridger T. Gunter, Andrew J. Payne, Jordan T. Yorgason, Scott C. Steffensen, Kyle B. Bills
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1593 (2024)
Exercise has increasingly been recognized as an adjunctive therapy for alcohol-use disorder (AUD), yet our understanding of its underlying neurological mechanisms remains limited. This knowledge gap impedes the development of evidence-based exercise
Externí odkaz:
https://doaj.org/article/86ad168a4c3b461a87d04dfa0a19de4c
Autor:
Kiran J. Mcloughlin, Afnan M. Aladdad, Andrew J. Payne, Anna I. Boda, Sayra Nieto-Gomez, Karl E. Kador
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Purified Retinal Ganglion Cells (RGCs) for in vitro study have been a valuable tool in the study of neural regeneration and in the development of therapies to treat glaucoma. Traditionally, RGCs have been isolated from early postnatal rats and mice,
Externí odkaz:
https://doaj.org/article/0a4cf6a1a0c249ec943334a27fcfd0ce
Autor:
R. Scott Duncan, Sean M. Riordan, Conner W. Hall, Andrew J. Payne, Kent D. Chapman, Peter Koulen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
N-acyl amides (NAAs) are a class of lipids that consist of an acyl group N-linked to an amino acid, neurotransmitter, taurine or ethanolamide group (N-acylethanolamines or NAEs) and include some endocannabinoids (eCB) such as anandamide. These lipids
Externí odkaz:
https://doaj.org/article/0d17e40471bf4198992004878889072f
Autor:
Ashley C. Nelson, Stephanie B. Williams, Stephanie S. Pistorius, Hyun J. Park, Taylor J. Woodward, Andrew J. Payne, J. Daniel Obray, Samuel I. Shin, Jennifer K. Mabey, Scott C. Steffensen
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The neural mechanisms underlying alcohol dependence are not well-understood. GABAergic neurons in the ventral tegmental area (VTA) are a relevant target for ethanol. They are inhibited by ethanol at physiologically-relevant levels in vivo and display
Externí odkaz:
https://doaj.org/article/cfedb0f2c074461f9e5197f44a1125c2
Publikováno v:
Molecules, Vol 19, Iss 6, Pp 7327-7340 (2014)
Resveratrol is a naturally occurring compound contributing to cellular defense mechanisms in plants. Its use as a nutritional component and/or supplement in a number of diseases, disorders, and syndromes such as chronic diseases of the central nervou
Externí odkaz:
https://doaj.org/article/5469aad8121e446f9495057267432110
Publikováno v:
Molecules, Vol 15, Iss 3, Pp 1168-1195 (2010)
Both acute and chronic degenerative diseases of the nervous system reduce the viability and function of neurons through changes in intracellular calcium signaling. In particular, pathological increases in the intracellular calcium concentration promo
Externí odkaz:
https://doaj.org/article/f318fa58759544b8bd1ad41a60acfd5f
Autor:
Hyun J. Park, Jennifer K. Mabey, J Daniel Obray, Stephanie S. Pistorius, Samuel I. Shin, Taylor J. Woodward, Andrew J. Payne, Ashley C. Nelson, Stephanie B. Williams, Scott C. Steffensen
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Frontiers in Neuroscience
Frontiers in Neuroscience
The neural mechanisms underlying alcohol dependence are not well-understood. GABAergic neurons in the ventral tegmental area (VTA) are a relevant target for ethanol. They are inhibited by ethanol at physiologically-relevant levels in vivo and display
Publikováno v:
Current Protocols in Toxicology
Drug discovery heavily relies on cell viability studies to assess the potential toxicity of drug candidates. L-Lactate dehydrogenase (LDH) is a cytoplasmic enzyme that catalyzes the concomitant interconversions of pyruvate to L-lactate and NADH to NA
Autor:
Vidhi V. Shah, Nathalie Sumien, Michael J. Forster, Andrew J. Payne, Simon Kaja, Alexandra N. Maynard, Imran Puthawala, Nitasha Khullar, Peter Koulen
Publikováno v:
Molecular Neurobiology. 52:545-554
Mutations in presenilin (PS) proteins cause familial Alzheimer’s disease. We herein tested the hypothesis that the expression levels of PS proteins are differentially affected during healthy aging, in the absence of pathological mutations. We used