Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrew J. Musacchio"'
Autor:
David C. Miller, Trevor C. Sherwood, Andrew J. Musacchio, Jacob M. Ganley, Robert R. Knowles, William R. Ewing
Publikováno v:
J Am Chem Soc
We report here a photocatalytic method for the intermolecular anti-Markovnikov hydroamination of unactivated olefins with primary alkyl amines to selectively furnish secondary amine products. These reactions proceed through aminium radical cation (AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b30a261e0ae7a8e6fa5229e047ee44c
https://doi.org/10.1021/jacs.9b08746
https://doi.org/10.1021/jacs.9b08746
Publikováno v:
J Am Chem Soc
With hundreds of unique members isolated to date, guaianolide lactones represent a particularly prolific class of terpene natural products. Given their extensive documented therapeutic properties and fascinating chemical structures, these metabolites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a800c7e63ed412700d4b166ab94e378
https://europepmc.org/articles/PMC6818654/
https://europepmc.org/articles/PMC6818654/
Publikováno v:
Journal of the American Chemical Society. 136:12217-12220
While olefin amination with aminium radical cations is a classical method for C-N bond formation, catalytic variants that utilize simple 2° amine precursors remain largely undeveloped. Herein we report a new visible-light photoredox protocol for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9d0210778cc0a257ddcd57fa3980e5
https://doi.org/10.1021/ja5056774
https://doi.org/10.1021/ja5056774
Autor:
Trevor C. Sherwood, Saeed G. Naguib, Robert R. Knowles, Andrew J. Musacchio, Brendan C. Lainhart, Xin Zhang
Publikováno v:
Science (New York, N.Y.). 355(6326)
Hydroamination gets a light push uphill Hydroamination of olefins is a broadly useful method for making carbon-nitrogen bonds. However, when both the amine and the olefin have multiple alkyl substituents, the reaction can become energetically unfavor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7f066c3a749e771470a777b9e13584
https://pubmed.ncbi.nlm.nih.gov/28209858
https://pubmed.ncbi.nlm.nih.gov/28209858
Autor:
Timothy Noël, Andrew J. Musacchio
Publikováno v:
Organic Letters. 13:5180-5183
General continuous-flow conditions for the Suzuki-Miyaura cross-coupling of heteroaryl halides and (hetero)arylboronic acids have been developed. A wide range of heterobiaryl products is obtained in excellent yields (20 examples) employing low cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5999e1a7429046bc0a4b64717a165eb
https://doi.org/10.1021/ol202052q
https://doi.org/10.1021/ol202052q
Publikováno v:
ChemInform. 46
While olefin amination with aminium radical cations is a classical method for C–N bond formation, catalytic variants that utilize simple 2° amine precursors remain largely undeveloped. Herein we report a new visible-light photoredox protocol for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6866b3f9ddedfa8a658794c9f7f16346
https://doi.org/10.1002/chin.201512161
https://doi.org/10.1002/chin.201512161
Autor:
Timothy Noël, Andrew J. Musacchio
Publikováno v:
ChemInform. 43
The reaction is applied to a wide range of heteroaromatic chlorides, bromides and triflates and aromatic and heteroaromatic boronic acids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9adfedcc3f7da7c3bcc2472ef73de0c
https://doi.org/10.1002/chin.201206085
https://doi.org/10.1002/chin.201206085
Publikováno v:
ChemInform. 42
A continuous-flow microfluidic system is developed for the transformation of phenols into their corresponding aryl triflates followed by Suzuki—Miyaura cross-coupling reaction to afford biaryls directly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::883b298791f3c0b5e5ad19aff90b713a
https://doi.org/10.1002/chin.201143082
https://doi.org/10.1002/chin.201143082
Autor:
Timothy NoeÌl, Andrew J. Musacchio
Publikováno v:
Organic Letters; Oct2011, Vol. 13 Issue 19, p5180-5183, 4p