Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Andrew J. McKnight"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mucus secretion is an important feature of asthma that highly correlates with morbidity. Current therapies, including administration of mucolytics and anti-inflammatory drugs, show limited effectiveness and durability, underscoring the need for novel
Externí odkaz:
https://doaj.org/article/9fee9093b2864a16a259f82823701e65
Autor:
A. Neil Barclay, Marion H. Brown, S. K. Alex K. Alex Law, Andrew J. McKnight, Michael G. Tomlinson, P. Anton van der Merwe
A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key referenc
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Mucus secretion is an important feature of asthma that highly correlates with morbidity. Current therapies, including administration of mucolytics and anti-inflammatory drugs, show limited effectiveness and durability, underscoring the need for novel
Autor:
Enrique Rodriguez, Benjamin J Schmiedel, Kenneth C. Kalunian, Pandurangan Vijayanand, Andrew J. McKnight, Bharat Panwar, Grégory Seumois, Rachel Soloff, Brandie White, Ferhat Ay, Shu Liang
Publikováno v:
Genome Res
Systemic lupus erythematosus (SLE) is an incurable autoimmune disease disproportionately affecting women. A major obstacle in finding targeted therapies for SLE is its remarkable heterogeneity in clinical manifestations as well as in the involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c8706419841b0363df0b58efab5504
https://europepmc.org/articles/PMC8015858/
https://europepmc.org/articles/PMC8015858/
Autor:
Bharat Panwar, Benjamin J Schmiedel, Grégory Seumois, Kenneth C. Kalunian, Shu Liang, Enrique Rodriguez, Andrew J. McKnight, Pandurangan Vijayanand, Ferhat Ay, Rachel Soloff, Brandie White
The systemic lupus erythematosus (SLE) is an incurable autoimmune disease disproportionately affecting women and may lead to damage in multiple different organs. The marked heterogeneity in its clinical manifestations is a major obstacle in finding t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5eba7f95160355cfae187bb36c0929e
https://doi.org/10.1101/2020.04.27.065227
https://doi.org/10.1101/2020.04.27.065227
Publikováno v:
Immunology. 132:503-515
The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 are involved in variety of inflammatory disorders including multiple sclerosis, rheumatoid arthritis, psoriasis and sarcoidosis. Two alternatively spliced variants of the human CXC
Autor:
Mireille H. Lahoud, Neil Ward, Irina Caminschi, Eugene Maraskovsky, Mariam Sofi, Stéphane Vandenabeele, Ken Shortman, Mark D. Wright, Andrew J McKnight, Thomas C. Brodnicki, Tracey Toy
Publikováno v:
DNA Sequence. 17:8-14
The epidermal growth factor-transmembrane seven (EGF-TM7) family are proteins that express EGF-like domains at their extracellular N-terminus coupled to a classical seven transmembrane (TM7) cassette. Recently, we identified, in mice, a novel member
Autor:
Carmel M. Quinn, Siamon Gordon, Mark R. Addley, Andrew J. McKnight, Alison J. Macfarlane, David R. Greaves, Dawn O'Reilly
Publikováno v:
Genomics. 84:1030-1040
This study has investigated the transcriptional regulation of the Emr1 gene in murine macrophages and defined an enhancer element within the proximal promoter that is necessary for Emr1 expression in myeloid cells. This element consists of an extende
Autor:
Lyn Jones, Andrew J McKnight
This book illustrates the successful partnership of chemistry and biology to advance successful biotherapeutic modalities. Molecular design to create function is common to both chemical and molecular biology, and this text highlights recent developme
Autor:
Andrew J. McKnight, Evelyne Schaller, Siamon Gordon, Klaus Pfeffer, Rudolf A. Rupec, Alison J. Macfarlane
Publikováno v:
Molecular and Cellular Biology. 22:8035-8043
Macrophages play a crucial role in the defense against pathogens. Distinct macrophage populations can be defined by the expression of restricted cell surface proteins. Resident tissue macrophages, encompassing Kupffer cells of the liver and red pulp