Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew J. Madden"'
Autor:
Lauren S.L. Price, Judith N. Rivera, Andrew J. Madden, Leah B. Herity, Joseph A. Piscitelli, Savannah Mageau, Charlene M. Santos, Jose R. Roques, Bentley Midkiff, Nana N. Feinberg, David Darr, Sha X. Chang, William C. Zamboni
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Minibeam radiation therapy is an experimental radiation therapy utilizing an array of parallel submillimeter planar X-ray beams. In preclinical studies, minibeam radiation therapy has been shown to eradicate tumors and cause significantly
Externí odkaz:
https://doaj.org/article/740570a053e546c4b20b6d47a8927c6a
Autor:
Andrew T. Lucas, Manuel Sanchez-Felix, Rose T. Ajamie, Alberto Gabizon, William C. Zamboni, Zack A. Kornblum, Palaniappan Kulanthaivel, David M. Bender, Leah B. Herity, Andrew J. Madden, Alexander V. Kabanov, Henry A. Havel
Publikováno v:
International Journal of Pharmaceutics. 526:443-454
Studies have shown that nanoparticles (NPs) are cleared through the mononuclear phagocyte system (MPS). Pharmacokinetic studies of Doxil, DaunoXome, micellar doxorubicin (SP1049C) and small molecule (SM) doxorubicin were performed in SCID mice, Sprag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb01bb5687d7fc4af1e6a55e0c1915fd
https://doi.org/10.1016/j.ijpharm.2017.04.079
https://doi.org/10.1016/j.ijpharm.2017.04.079
Autor:
William C. Zamboni, Savannah Mageau, Andrew J. Madden, Joseph A. Piscitelli, Bentley R. Midkiff, Lauren S.L. Price, Sha Chang, Jose R. Roques, Nana N. Feinberg, Leah B. Herity, Judith N. Rivera, David B. Darr, Charlene M. Santos
Publikováno v:
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Minibeam radiation therapy is an experimental radiation therapy utilizing an array of parallel submillimeter planar X-ray beams. In preclinical studies, minibeam radiation therapy has been shown to eradicate tumors and cause significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18546c58e16ac9648be95fdad67637f5
https://doi.org/10.1177/17588359211053700
https://doi.org/10.1177/17588359211053700
Publikováno v:
WIREs Nanomedicine and Nanobiotechnology. 8:642-653
Major advances in carrier-mediated agents (CMAs), which include nanoparticles and conjugates, have revolutionized drug delivery capabilities over the past decade. While providing numerous advantages over their small-molecule counterparts, there is su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1e5cb0af3848e23dff2a0547fef914
https://doi.org/10.1002/wnan.1394
https://doi.org/10.1002/wnan.1394
Autor:
Steven A. Lommel, P. Vennam, B. Oberhardt, Stefan Franzen, Charlene M. Santos, William C. Zamboni, D. Arney, Dustin M. Lockney, C. R. Miller, Andrew J. Madden, Paola A. Gehrig
Publikováno v:
Nanomedicine (London, England). 12(20)
Aim: To compare the pharmacokinetics and efficacy of doxorubicin containing plant virus nanoparticles (PVNs) with PEGylated liposomal doxorubicin (PLD) and small molecule doxorubicin in two mouse models of cancer. Materials & methods: Studies were pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef8614bd5a651eb2e443d30fb7b8dab
https://pubmed.ncbi.nlm.nih.gov/28952882
https://pubmed.ncbi.nlm.nih.gov/28952882
Publikováno v:
Pharmaceutical Nanotechnology: Innovation and Production ISBN: 9783527800681
Pharmaceutical Nanotechnology: Innovation and Production
Pharmaceutical Nanotechnology: Innovation and Production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dbdaaf3d0795b53469adf99db33b388
https://doi.org/10.1002/9783527800681.ch19
https://doi.org/10.1002/9783527800681.ch19
Autor:
William C. Zamboni, Andrew Z. Wang, Lei Peng, James C. Luft, Mathew C. Finniss, Joseph M. DeSimone, Allison N. Schorzman, Charles J. Bowerman, Andrew J. Madden, Kevin S. Chu
Publikováno v:
Biomaterials. 34:8424-8429
Nanoparticle (NP) drug loading is one of the key defining characteristics of an NP formulation. However, the effect of NP drug loading on therapeutic efficacy and pharmacokinetics has not been thoroughly evaluated. Herein, we characterized the effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7405a84804307ca6a055b1d3f2996719
https://doi.org/10.1016/j.biomaterials.2013.07.038
https://doi.org/10.1016/j.biomaterials.2013.07.038
Formulation and physiologic factors affecting the pharmacology of carrier-mediated anticancer agents
Publikováno v:
Expert opinion on drug metabolismtoxicology. 11(9)
Major advances in carrier-mediated agents (CMAs), which include nanoparticles and conjugates, have revolutionized drug delivery capabilities over the past decade. While providing numerous advantages such as increased exposure duration, greater solubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188f51ff299c86276ee007663a645ced
https://pubmed.ncbi.nlm.nih.gov/26173794
https://pubmed.ncbi.nlm.nih.gov/26173794
Autor:
Whitney P Kirschbrown, William C. Zamboni, Andrew J. Madden, Gina Song, Jennifer S. Petschauer
Publikováno v:
Nanomedicine (London, England). 10(3)
Major advances in carrier-mediated agents, which include nanoparticles, nanosomes and conjugates, have revolutionized drug delivery capabilities over the past decade. While providing numerous advantages, such as greater solubility, duration of exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cbb47338161650110011974c3e354c
https://pubmed.ncbi.nlm.nih.gov/25707978
https://pubmed.ncbi.nlm.nih.gov/25707978
Autor:
William C. Zamboni, Charlene M. Santos, Leah B. Herity, David B. Darr, Andrew J. Madden, Judith N. Rivera, Lauren S.L. Price, Sha Chang, Jose R. Roques
Publikováno v:
Cancer Research. 77:5051-5051
Background: Recent meta-analyses have reported that the tumor delivery of nanoparticles (NPs) is lower than expected and inefficient. Thus, there is a strong need to develop new methods to enhance the tumor delivery of NPs without increasing toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6634bfe4b47d1a25d1321b979f34e0f
https://doi.org/10.1158/1538-7445.am2017-5051
https://doi.org/10.1158/1538-7445.am2017-5051