Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Andrew J. Lewin"'
Autor:
Andrew J Lewin, Juan P Frías
Publikováno v:
Expert Opinion on Pharmacotherapy. 16:781-784
The combination of metformin and a sulfonylurea is commonly used in type 2 diabetes mellitus. Many patients on this combination therapy do not achieve or maintain glycemic targets and require the addition of a third antihyperglycemic agent. Among the
Publikováno v:
Clinical Therapeutics. 35:142-152
Elevated systolic blood pressure (SBP) is an independent risk factor for cardiovascular events and mortality.The goal of this study was to assess whether nebivolol (NEB), a vasodilatory β(1)-selective blocker, is a safe and efficacious monotherapy f
Autor:
Matthew R. Weir, Andrew J. Lewin
Publikováno v:
Clinical Therapeutics. 30:2354-2365
This was a post hoc subgroup analysis of efficacy and tolerability data from the Irbesartan/HCTZ Blood Pressure Reductions in Diverse Patient Populations (INCLUSIVE) trial stratified by baseline body mass index (BMI). The BMI subgroup data were also
Autor:
Tu T. Nguyen, Steven G. Terra, Xiang Gao, Charles F. Contant, Andrew J. Lewin, Omar L. Francone
Publikováno v:
The American Journal of Cardiology. 102:434-439
The weak peroxisome proliferator activated receptor-alpha (PPAR-alpha) agonists gemfibrozil and fenofibrate achieve only small increases in high-density lipoprotein (HDL) cholesterol. CP-778,875 is a more potent PPAR-alpha agonist developed to produc
Publikováno v:
Clinical Therapeutics. 29:844-855
Metformin is widely used in the management of type 2 diabetes, either as monotherapy or in combination with other oral antihyperglycemic agents such as sulfonylureas and thiazolidinediones. Combination treatment with metformin and sulfonylurea in pat
Autor:
Andrew J, Lewin, Juan P, Frías
Publikováno v:
Diabetes Care
OBJECTIVE To investigate the efficacy and tolerability of empagliflozin as add-on to metformin and sulfonylurea in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Patients inadequately controlled on metformin and sulfonylurea (HbA1c ≥7 t
Autor:
Myron H. Weinberger, Gordon H. Williams, Andrew J. Lewin, Scott Krause, Murray Epstein, Bruce Beckerman, Rajiv Patni, Robin Mukherjee
Publikováno v:
Clinical Journal of the American Society of Nephrology. 1:940-951
Previous studies have shown that the selective aldosterone blocker eplerenone, in doses of up to 200 mg/d, reduces albuminuria in patients with type 2 diabetes. This study was conducted to ascertain whether lower doses of eplerenone (50 or 100 mg/d)
Autor:
George L. Bakris, Kellie Leight, Gilbert W. Gleim, Santosh Sutradhar, Jonathan C. Fox, Andrew J. Lewin, Laura A. Demopoulos
Publikováno v:
J Clin Hypertens (Greenwich)
The JNC 7 states that persons with blood pressure (BP) more than 20/10 mm Hg above goal should be started on combination drug therapy. This criterion includes patients with BP >160/100 mm Hg and diabetics with hypertension. The goal BP for persons wi
Autor:
Yale B. Mitchel, William Insull, Michael J. Koren, Andrew J. Lewin, Meehyung Cho, Michelle Sidisin, James M. McKenney, Ted Feldman, Debra Kush, Sukrut Shah, Helmut G. Schrott
Publikováno v:
The American Journal of Cardiology. 93:1481-1486
This study assessed whether the co-administration of ezetimibe and simvastatin would be more effective than simvastatin monotherapy in allowing high-risk patients to achieve a low-density lipoprotein (LDL) cholesterol goal of100 mg/dl. Men and women
Autor:
Andrew J, Lewin, Dean J, Kereiakes, Steven G, Chrysant, Joseph L, Izzo, Suzanne, Oparil, James, Lee, Victor, Fernandez, Michael, Melino
Publikováno v:
Ethnicitydisease. 24(1)
Evaluate efficacy/safety of olmesartan medoxomil (OM)/amlodipine (AML)/ hydrochlorothiazide (HCTZ) in Hispanic/Latino adults with hypertension.Randomized, double-blind, 12-week, parallel-group study followed by a 40-week open-label extension phase.Cl