Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew J. Kukor"'
Autor:
Madeleine C. Deem, Isabelle Cai, Joshua S. Derasp, Paloma L. Prieto, Yusuke Sato, Junliang Liu, Andrew J. Kukor, Jason E. Hein
Publikováno v:
ACS Catalysis. 13:1418-1430
Autor:
Andrew J. Kukor, Noah Depner, Isabelle Cai, John L. Tucker, Jeffrey C. Culhane, Jason E. Hein
Publikováno v:
Chemical Science. 13:10765-10772
A novel enantioselective route to tetrabenazine has been developed using continuous CIDT in a multiwell crystallization/racemization device outfitted with real-time HPLC to visualize and control the dynamic process.
Autor:
Andrew J. Kukor, Frédéric St-Jean, Andreas Stumpf, Thomas C. Malig, Katarzyna A. Piechowicz, Kenji Kurita, Jason E. Hein
Publikováno v:
Reaction Chemistry & Engineering.
The crystallization-induced diastereomer transformation of a precursor to navoximod was investigated using online HPLC and optimized with inline racemization.
Autor:
Derek J. Schipper, Robert C. M. Claridge, W. Scott Hopkins, Andrew J. Kukor, Geoffrey S. Sinclair
Publikováno v:
Chemical Science
Non-covalent bonding interactions, such as chalcogen bonding, can have a substantial effect on the electronic and physical properties of conjugated polymers and is largely dependent on the strength of interaction. Functional groups that are tradition
Publikováno v:
Reaction Chemistry & Engineering. 6:2042-2049
Current PAT tools struggle to provide real time solid-phase composition data for crystallizations. HPLC offers a variety of benefits over other solution-phase PATs and can be used to infer solid-phase composition when combining total (solid plus solu
Publikováno v:
Chemistry–Methods. 2
Autor:
Andrew J, Kukor, Noah, Depner, Isabelle, Cai, John L, Tucker, Jeffrey C, Culhane, Jason E, Hein
Publikováno v:
Chemical science. 13(36)
A multi-well continuous CIDT approach with inline racemization of the solution phase is presented. Using two in-house built PATs and a flow reactor, we were able to successfully crystallize an enantiopure salt of TBZ, the active metabolite of the tar
Publikováno v:
Macromolecules. 53:5169-5176
The development of economical synthetic methods remains an important step toward the widespread use of conjugated polymers. Most well-established methods require either prefunctionalization with or...
Autor:
Andrew J. Kukor, Cochran Brian M, Junliang Liu, Jason E. Hein, Kucera David, Jeffrey C. Culhane, John L. Tucker, Yusuke Sato
Publikováno v:
The Journal of organic chemistry. 86(20)
Solid-liquid slurries are vital and increasingly prevalent in the pharmaceutical and chemical industries. Despite the importance of these heterogeneous systems, process control and optimization are fundamentally hindered by a lack of compatible real-
Synthesis of Poly(heteroarylenevinylene) Derivatives via Rhodium-Catalyzed Hydroarylation of Alkynes
Publikováno v:
Synlett. 29:2552-2556
Organic electronics has developed into a significant field of research and industry in the last decade. The progress has been enabled by the many advancements made in synthetic technologies, which allow for the design of a plethora of interesting mat