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pro vyhledávání: '"Andrew J. Knappenberger"'
Autor:
Sneha Grandhi, Rajesh Viswanathan, Md. Faiz Ahmad, Andrew J. Knappenberger, Michael E. Harris, Reena Sheth
Publikováno v:
Journal of Biological Chemistry. 292:16463-16476
Eukaryotic class I ribonucleotide reductases (RRs) generate deoxyribonucleotides for DNA synthesis. Binding of dNTP effectors is coupled to the formation of active dimers and induces conformational changes in a short loop (loop 2) to regulate RR spec
Autor:
Michael E. Harris, Andrew J. Knappenberger, Rajesh Viswanathan, Chris Dealwis, Md. Faiz Ahmad
Publikováno v:
Biochemistry. 55:5884-5896
Class I ribonucleotide reductase (RR) maintains balanced pools of deoxyribonucleotide substrates for DNA replication by converting ribonucleoside diphosphates (NDPs) to 2'-deoxyribonucleoside diphosphates (dNDPs). Binding of deoxynucleoside triphosph