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pro vyhledávání: '"Andrew J. Kavran"'
Autor:
Andrew J. Kavran, Aaron Clauset
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background Large-scale biological data sets are often contaminated by noise, which can impede accurate inferences about underlying processes. Such measurement noise can arise from endogenous biological factors like cell cycle and life histor
Externí odkaz:
https://doaj.org/article/bd8467f6762c426d9b93304b4003a75a
Autor:
Andrew J, Kavran, Scott A, Stuart, Kristyn R, Hayashi, Joel M, Basken, Barbara J, Brandhuber, Natalie G, Ahn
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(12)
Patients with melanoma receiving drugs targeting BRAFV600E and mitogen-activated protein (MAP) kinase kinases 1 and 2 (MEK1/2) invariably develop resistance and face continued progression. Based on preclinical studies, intermittent treatment involvin
Autor:
N. Doherty Garcia, T. Jourabchi, Sara L. Sawyer, N. Lammer, Aaron Clauset, Michael J. Smallegan, T. S. Brant, Steve Miller, Andrew J Kavran, V. DuMont, M. Palacio, Nicholas J. Cordaro
Despite substantial standardization, polymerase chain reaction (PCR) experiments frequently fail. Troubleshooting failed PCRs can be costly in both time and money. Using a crowdsourced data set spanning 290 real PCRs from six active research laborato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112623724e5df1de6862052df4950307
https://doi.org/10.1101/2021.08.12.455589
https://doi.org/10.1101/2021.08.12.455589
Autor:
Aaron Clauset, Andrew J Kavran
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)
Large-scale biological data sets, e.g., transcriptomic, proteomic, or ecological, are often contaminated by noise, which can impede accurate inferences about underlying processes. Such measurement noise can arise from endogenous biological factors li
Autor:
Natalie G. Ahn, Christopher C. Ebmeier, Scott A. Stuart, Thomas Lee, Joel Basken, William M. Old, Andrew J. Kavran
Publikováno v:
Molecularcellular proteomics : MCP. 17(4)
The BRAF-MKK1/2-ERK1/2 pathway is constitutively activated in response to oncogenic mutations of BRAF in many cancer types, including melanoma. Although small molecules that inhibit oncogenic BRAF and MAP kinase kinase (MKK)1/2 have been successful i