Výsledky vyhledávání - "Andrew J. Heilpern"

Matrix Metalloproteinase 9 Plays a Key Role in Lyme Arthritis but Not in Dissemination of Borrelia burgdorferi

Autor: Linden T. Hu, Andrew J. Heilpern, George Perides, Roderick T. Bronson, Warren Wertheim, Jia He

Publikováno v: Infection and Immunity. 77:2643-2649

Borrelia burgdorferi , the causative agent of Lyme arthritis, does not produce any exported proteases capable of degrading extracellular matrix despite the fact that it is able to disseminate from a skin insertion site to infect multiple organs. Prio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1502996bb0c99b7545883c9e58f112f1
https://doi.org/10.1128/iai.00214-09

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pIII CTX , a Predicted CTXφ Minor Coat Protein, Can Expand the Host Range of Coliphage fd To Include Vibrio cholerae

Autor: Andrew J. Heilpern, Matthew K. Waldor

Publikováno v: Journal of Bacteriology. 185:1037-1044

CTXφ is a filamentous bacteriophage that encodes cholera toxin. CTXφ infection of its host bacterium, Vibrio cholerae , requires the toxin-coregulated pilus (TCP) and the products of the V. cholerae tolQRA genes. Here, we have explored the role of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1958fa10877de9d87950d75be9a4b2e6
https://doi.org/10.1128/jb.185.3.1037-1044.2003

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Molecular analyses of a putative CTXphi precursor and evidence for independent acquisition of distinct CTX(phi)s by toxigenic Vibrio cholerae

Autor: Matthew K. Waldor, E. Fidelma Boyd, Andrew J. Heilpern

Publikováno v: Journal of bacteriology. 182(19)

The genes encoding cholera toxin ( ctxA and ctxB ) are encoded in the genome of CTXφ, a filamentous phage that infects Vibrio cholerae . To study the evolutionary history of CTXφ, we examined genome diversity in CTXφs derived from a variety of epi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111d1680ecb217716db07e1cbf4f032e
https://pubmed.ncbi.nlm.nih.gov/10986258

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The Carboxyl Terminus of v-Abl Protein Can Augment SH2 Domain Function

Autor: David Warren, Naomi Rosenberg, Andrew J. Heilpern, Kent Berg

Abelson murine leukemia virus (Ab-MLV) transforms NIH 3T3 and pre-B cells via expression of the v-Abl tyrosine kinase. Although the enzymatic activity of this molecule is absolutely required for transformation, other regions of the protein are also i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f279af6ece97ead9e633ba50f6b16e
https://europepmc.org/articles/PMC111963/

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CTXphi infection of Vibrio cholerae requires the tolQRA gene products

Autor: Andrew J. Heilpern, Matthew K. Waldor

Publikováno v: Journal of bacteriology. 182(6)

CTXφ is a lysogenic filamentous bacteriophage that encodes cholera toxin. Filamentous phages that infect Escherichia coli require both a pilus and the products of tolQRA in order to enter host cells. We have previously shown that toxin-coregulated p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818f6cdefa96a5bc1be339104d604732
https://pubmed.ncbi.nlm.nih.gov/10692381

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