Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Andrew J. Gifford"'
Autor:
Chelsea Mayoh, Andrew J. Gifford, Rachael Terry, Loretta M. S. Lau, Marie Wong, Padmashree Rao, Tyler Shai-Hee, Federica Saletta, Dong-Anh Khuong-Quang, Vicky Qin, Marion K. Mateos, Deborah Meyran, Katherine E. Miller, Aysen Yuksel, Emily V. A. Mould, Rachel Bowen-James, Dinisha Govender, Akanksha Senapati, Nataliya Zhukova, Natacha Omer, Hetal Dholaria, Frank Alvaro, Heather Tapp, Yonatan Diamond, Luciano Dalla Pozza, Andrew S. Moore, Wayne Nicholls, Nicholas G. Gottardo, Geoffrey McCowage, Jordan R. Hansford, Seong-Lin Khaw, Paul J. Wood, Daniel Catchpoole, Catherine E. Cottrell, Elaine R. Mardis, Glenn M. Marshall, Vanessa Tyrrell, Michelle Haber, David S. Ziegler, Orazio Vittorio, Joseph A. Trapani, Mark J. Cowley, Paul J. Neeson, Paul G. Ekert
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Molecular profiling of the tumour immune microenvironment (TIME) has enabled the rational choice of immunotherapies in some adult cancers. In contrast, the TIME of paediatric cancers is relatively unexplored. We speculated that a
Externí odkaz:
https://doaj.org/article/fbd7979e6f4b4aebb70a711623639d1f
Autor:
Pamela Ajuyah, Chelsea Mayoh, Loretta M. S. Lau, Paulette Barahona, Marie Wong, Hazel Chambers, Fatima Valdes-Mora, Akanksha Senapati, Andrew J. Gifford, Colleen D’Arcy, Jordan R. Hansford, Neevika Manoharan, Wayne Nicholls, Molly M. Williams, Paul J. Wood, Mark J. Cowley, Vanessa Tyrrell, Michelle Haber, Paul G. Ekert, David S. Ziegler, Dong-Anh Khuong-Quang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Diffuse midline gliomas (DMG) harbouring H3K27M mutation are paediatric tumours with a dismal outcome. Recently, a new subtype of midline gliomas has been described with similar features to DMG, including loss of H3K27 trimethylation, but la
Externí odkaz:
https://doaj.org/article/8e8fabf3268f4381b287194aa795890c
Autor:
Rebecca Daly, Kate Hetherington, Emily Hazell, Bethany R. Wadling, Vanessa Tyrrell, Katherine M. Tucker, Glenn M. Marshall, David S. Ziegler, Loretta M. S. Lau, Toby N. Trahair, Tracey A. O’Brien, Kiri Collins, Andrew J. Gifford, Michelle Haber, Mark Pinese, David Malkin, Mark J. Cowley, Jonathan Karpelowsky, Donna Drew, Chris Jacobs, Claire E. Wakefield
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 7, p 1033 (2023)
Precision medicine programs aim to utilize novel technologies to identify personalized treatments for children with cancer. Delivering these programs requires interdisciplinary efforts, yet the many groups involved are understudied. This study explor
Externí odkaz:
https://doaj.org/article/ebb8f8472a954e148f3f353dc5bb6b5d
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 3, Iss 7, Pp 272-275 (2015)
We report the case and follow up of a 4 year old girl who was born with esophageal atresia and was found to have concomitant Barrett's esophagus and eosinophilic esophagitis. Development of metaplasia has generally been regarded as a chronic, long te
Externí odkaz:
https://doaj.org/article/a797c18a66d543bd9e3d2d74fb516065
Autor:
Wakefield, Rebecca Daly, Kate Hetherington, Emily Hazell, Bethany R. Wadling, Vanessa Tyrrell, Katherine M. Tucker, Glenn M. Marshall, David S. Ziegler, Loretta M. S. Lau, Toby N. Trahair, Tracey A. O’Brien, Kiri Collins, Andrew J. Gifford, Michelle Haber, Mark Pinese, David Malkin, Mark J. Cowley, Jonathan Karpelowsky, Donna Drew, Chris Jacobs, Claire E.
Publikováno v:
Journal of Personalized Medicine; Volume 13; Issue 7; Pages: 1033
Precision medicine programs aim to utilize novel technologies to identify personalized treatments for children with cancer. Delivering these programs requires interdisciplinary efforts, yet the many groups involved are understudied. This study explor
Autor:
Joel Vanderniet, Kristen A Neville, Louise S Conwell, Eva A Wegner, Maria E Craig, Susan Adams, Andrew J Gifford, Melissa Koutsiofi, Frances M Calabria, Gemma Maguire, Paul Thomas, Louise Campbell, Helen J Woodhead
Publikováno v:
Journal of Paediatrics and Child Health. 59:398-400
Autor:
Glenn M. Marshall, Belamy B. Cheung, Michael W. Parker, Giovanni Perini, Jamie I. Fletcher, Murray D. Norris, Michelle Haber, W. Clay Gustafson, Shizhen Zhu, Xiaoling Zhang, Tao Liu, Andrew J. Gifford, Matthias Fischer, Andre Oberthuer, Stefan Hüttelmaier, Larissa Doughty, Jessica L. Bell, Michael A. Gorman, Brendan W. Stevenson, Bryce Keenan, Chelsea Mayoh, Bing Liu, Joshua A. McCarroll, Jayne E. Murray, Giorgio Milazzo, Janith A. Seneviratne, Taylor Lim, Mika Herath, Olivia C. Ciampa, Daniel R. Carter, Hassina Massudi, Jessica K. Holien, Jessica Koach
Supplementary Figure S1. PA2G4 is a MYCN transactivation target gene. A, Quantification of protein expression using anti-PA2G4 and anti-MYCN antibodies against whole cell protein lysates from BE(2)-C and Kelly cells, following MYCN siRNA knockdown fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60025d7d24b347241cbbcf5c562a70ea
https://doi.org/10.1158/0008-5472.22426183.v1
https://doi.org/10.1158/0008-5472.22426183.v1
Autor:
Glenn M. Marshall, Belamy B. Cheung, Michael W. Parker, Giovanni Perini, Jamie I. Fletcher, Murray D. Norris, Michelle Haber, W. Clay Gustafson, Shizhen Zhu, Xiaoling Zhang, Tao Liu, Andrew J. Gifford, Matthias Fischer, Andre Oberthuer, Stefan Hüttelmaier, Larissa Doughty, Jessica L. Bell, Michael A. Gorman, Brendan W. Stevenson, Bryce Keenan, Chelsea Mayoh, Bing Liu, Joshua A. McCarroll, Jayne E. Murray, Giorgio Milazzo, Janith A. Seneviratne, Taylor Lim, Mika Herath, Olivia C. Ciampa, Daniel R. Carter, Hassina Massudi, Jessica K. Holien, Jessica Koach
Supplementary Figure S1. F, Confocal microscopy of SHEP Tet21N cells using anti-PA2G4 (red) and anti-MYCN (green) antibodies. G, Immunoblot analysis of cytoplasmic and nuclear fractions from BE(2)-C and Kelly human neuroblastoma cell lines with antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d30f1f6671b089f475263f614b3c030
https://doi.org/10.1158/0008-5472.22426180
https://doi.org/10.1158/0008-5472.22426180
Autor:
Michelle Haber, Murray D. Norris, Katerina V. Gurova, Andrei V. Gudkov, David S. Ziegler, Anthony J. Cesare, Ricky W. Johnstone, Glenn Marshall, Jamie I. Fletcher, Michelle J. Henderson, Daniel R. Carter, Andrew J. Gifford, Alvin Kamili, Lei Zhai, Sophie Allan, Stephanie Alfred, Georgina Eden, Adam Kearns, Erin Mosmann, Jessica A. Pettitt, Frances K. Kusuma, Jennifer Brand, Hazel Quek, Pooja Venkat, Chelsea Mayoh, Aisling O'Connor, Katerina I. Leonova, Natalia Issaeva, Laura D. Gamble, Anahid Ehteda, Rachael Terry, Angelika Bongers, Emma Ronca, Mawar Karsa, Ruby Pandher, Jayne Murray, Klaartje Somers, Lin Xiao
HT10806TG_CBL0137 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a65865b88e665572993028e81a66b25
https://doi.org/10.1158/1078-0432.22481328.v1
https://doi.org/10.1158/1078-0432.22481328.v1
Autor:
Glenn M. Marshall, Belamy B. Cheung, Michael W. Parker, Giovanni Perini, Jamie I. Fletcher, Murray D. Norris, Michelle Haber, W. Clay Gustafson, Shizhen Zhu, Xiaoling Zhang, Tao Liu, Andrew J. Gifford, Matthias Fischer, Andre Oberthuer, Stefan Hüttelmaier, Larissa Doughty, Jessica L. Bell, Michael A. Gorman, Brendan W. Stevenson, Bryce Keenan, Chelsea Mayoh, Bing Liu, Joshua A. McCarroll, Jayne E. Murray, Giorgio Milazzo, Janith A. Seneviratne, Taylor Lim, Mika Herath, Olivia C. Ciampa, Daniel R. Carter, Hassina Massudi, Jessica K. Holien, Jessica Koach
MYCN is a major driver for the childhood cancer, neuroblastoma, however, there are no inhibitors of this target. Enhanced MYCN protein stability is a key component of MYCN oncogenesis and is maintained by multiple feedforward expression loops involvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7722c088528eae6f7ee7e960f9d8b68
https://doi.org/10.1158/0008-5472.c.6512245
https://doi.org/10.1158/0008-5472.c.6512245