Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Andrew J. Dwork"'
Autor:
David S. Ruff, Ilaria Balbo, Ruo‐Yah Lai, Diarra Dieng, Charlotte Hennessey, Krish Vennam, Andrew J. Dwork, Morgan McCreary, Elan D. Louis, Phyllis L. Faust, Sheng‐Han Kuo
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 377-388 (2024)
Abstract Objective Postmortem examination of the essential tremor cerebellum has revealed a variety of pathological changes centered in and around Purkinje cells. Studies have predominantly focused on cerebellar neuronal connections. Bergmann glial m
Externí odkaz:
https://doaj.org/article/4b5a027e77934becaa5a906e6df8f236
Autor:
Robert C. Bransfield, Shiva Kumar Goud Gadila, Laura J. Kursawe, Andrew J. Dwork, Gorazd Rosoklija, Elizabeth J. Horn, Michael J. Cook, Monica E. Embers
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31159- (2024)
Background: Infectious diseases can contribute to substance abuse. Here, a fatal case of borreliosis and substance abuse is reported. This patient had a history of multiple tick bites and increasing multisystem symptoms, yet diagnosis and treatment w
Externí odkaz:
https://doaj.org/article/b659731d1ca34c2e88682b9b39be213d
Autor:
Zac Chatterton, Natalia Mendelev, Sean Chen, Walter Carr, Gary H. Kamimori, Yongchao Ge, Andrew J. Dwork, Fatemeh Haghighi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Sampling the live brain is difficult and dangerous, and withdrawing cerebrospinal fluid is uncomfortable and frightening to the subject, so new sources of real-time analysis are constantly sought. Cell-free DNA (cfDNA) derived from glia and neurons o
Externí odkaz:
https://doaj.org/article/0a2eae08fd784a2aa546b74bf8ce8bb8
Autor:
Shiva Kumar Goud Gadila, Gorazd Rosoklija, Andrew J. Dwork, Brian A. Fallon, Monica E. Embers
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
The complex etiology of neurodegenerative disease has prompted studies on multiple mechanisms including genetic predisposition, brain biochemistry, immunological responses, and microbial insult. In particular, Lyme disease is often associated with ne
Externí odkaz:
https://doaj.org/article/336876a7ee654925816735d133faea0a
Autor:
Antoine Besnard, Tomer Langberg, Sally Levinson, Duong Chu, Cinzia Vicidomini, Kimberly N. Scobie, Andrew J. Dwork, Victoria Arango, Gorazd B. Rosoklija, J. John Mann, René Hen, E. David Leonardo, Maura Boldrini, Amar Sahay
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3183-3196 (2018)
Summary: Stress exposure is associated with the pathogenesis of psychiatric disorders, including post-traumatic stress disorder (PTSD) and major depressive disorder (MDD). Here, we show in rodents that chronic stress exposure rapidly and transiently
Externí odkaz:
https://doaj.org/article/3c57edd6b6b14a11979a871628b1efed
Autor:
Jeremy D. Coplan, Shariful Syed, Tarique D. Perera, Sasha L. Fulton, Mary Ann Banerji, Andrew J. Dwork, John G. Kral
Publikováno v:
Neural Plasticity, Vol 2014 (2014)
Glucagon-like peptide-1 (GLP-1) regulates carbohydrate metabolism and promotes neurogenesis. We reported an inverse correlation between adult body mass and neurogenesis in nonhuman primates. Here we examine relationships between physiological levels
Externí odkaz:
https://doaj.org/article/2114332eca0c4e0a840c9267e98f815b
Autor:
Di Zhang, Yanxiang Deng, Petra Kukanja, Eneritz Agirre, Marek Bartosovic, Mingze Dong, Cong Ma, Sai Ma, Graham Su, Shuozhen Bao, Yang Liu, Yang Xiao, Gorazd B. Rosoklija, Andrew J. Dwork, J. John Mann, Kam W. Leong, Maura Boldrini, Liya Wang, Maximilian Haeussler, Benjamin J. Raphael, Yuval Kluger, Gonçalo Castelo-Branco, Rong Fan
Publikováno v:
Nature. 616:113-122
Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular states in the tissue context1–5. However, current methods capture only one layer of omics information at
Autor:
Mark D Underwood, Hanga Galfalvy, Shu-chi Hsiung, Yan Liu, Norman R Simpson, Mihran J Bakalian, Gorazd B Rosoklija, Andrew J Dwork, Victoria Arango, J John Mann
Publikováno v:
International Journal of Neuropsychopharmacology.
Background The hypothalamic-pituitary-adrenal (HPA) axis is a major stress response system, and excessive HPA responses can impact major depressive disorder and suicide. We examined relationships between reported early life adversity (ELA), recent li
Autor:
Aswathy Ammothumkandy, Kristine Ravina, Victoria Wolseley, Alexandria N. Tartt, Pen-Ning Yu, Luis Corona, Naibo Zhang, George Nune, Laura Kalayjian, J. John Mann, Gorazd B. Rosoklija, Victoria Arango, Andrew J. Dwork, Brian Lee, J. A. D. Smith, Dong Song, Theodore W. Berger, Christianne Heck, Robert H. Chow, Maura Boldrini, Charles Y. Liu, Jonathan J. Russin, Michael A. Bonaguidi
Publikováno v:
Nature Neuroscience. 25:493-503
The hippocampus is the most common seizure focus in people. In the hippocampus, aberrant neurogenesis plays a critical role in the initiation and progression of epilepsy in rodent models, but it is unknown whether this also holds true in humans. To a
Autor:
Allison L Soung, Abigail Vanderheiden, Anna S Nordvig, Cheick A Sissoko, Peter Canoll, Madeline B Mariani, Xiaoping Jiang, Traci Bricker, Gorazd B Rosoklija, Victoria Arango, Mark Underwood, J John Mann, Andrew J Dwork, James E Goldman, Adrianus C M Boon, Maura Boldrini, Robyn S Klein
Publikováno v:
Research Square
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Infection with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is associated with onset of neurological and psychiatric symptoms during and after the acute phase of illness1–4. Acute SARS-CoV-2 disease (COVID-19) presents with defi