Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Andrew J. Crossthwaite"'
Autor:
Judith, Blythe, Fergus G P, Earley, Katarzyna, Piekarska-Hack, Lucy, Firth, Julia, Bristow, Elizabeth A, Hirst, James A, Goodchild, Elke, Hillesheim, Andrew J, Crossthwaite
Publikováno v:
Pesticide Biochemistry and Physiology. 187:105217
Isocycloseram is a novel isoxazoline insecticide and acaricide with activity against lepidopteran, hemipteran, coleopteran, thysanopteran and dipteran pest species. Isocycloseram selectively targets the invertebrate Rdl GABA receptor at a site that i
Autor:
Ralf Nauen, Lindy Holden-Dye, Thomas Van Leeuwen, Franck E. Dayan, Andrew J. Crossthwaite, Geert Haesaert
Publikováno v:
Outlooks on Pest Management. 30:157-163
Autor:
Ann Sluder, Sheetal Shah, Jérôme Cassayre, Ralph Clover, Peter Maienfisch, Louis-Pierre Molleyres, Elizabeth A Hirst, Anthony J Flemming, Min Shi, Penny Cutler, Carole Stanger, Richard S Roberts, David J Hughes, Thomas Flury, Michael P Robinson, Elke Hillesheim, Thomas Pitterna, Fredrik Cederbaum, Paul A Worthington, Andrew J Crossthwaite, John D Windass, Richard A Currie, Fergus G P Earley
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e34712 (2012)
The efficacy of all major insecticide classes continues to be eroded by the development of resistance mediated, in part, by selection of alleles encoding insecticide insensitive target proteins. The discovery of new insecticide classes acting at nove
Externí odkaz:
https://doaj.org/article/01ae6528af6c47e98391b659caff9a2a
Autor:
Aurelien Bigot, Andrew J. Crossthwaite, Russell Slater, Robert J. Lind, Jim Goodchild, Philippe Camblin, Peter Maienfisch
Publikováno v:
Journal of Pesticide Science. 42:67-83
The nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel composed of 5 protein subunits arranged around a central cation selective pore. Several classes of natural and synthetic insecticides mediate their effect through interacting
Autor:
Andrew Edmunds, Dave Hughes, Anna Cristina Dutton, Olivier Loiseleur, André Stoller, Jean Wenger, Roger Graham Hall, Stephan Trah, Jagadish Pabba, Andrew J. Crossthwaite, André Jeanguenat, Patricia Durieux
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:403-427
The diamide insecticides act on the ryanodine receptor (RyR). The synthesis of various bicyclic anthranilic derivatives is reported. Their activity against the insect ryanodine receptor (RyR) and their insecticidal activity in the greenhouse is prese
Autor:
Daniel Cordova, Shinichi Banba, Vincent L. Salgado, Holly J.R. Popham, Toshifumi Nakao, Robert Kennedy, Shinsuke Fujioka, Ralf Nauen, Andrew J. Crossthwaite, Gerald B. Watson, Barbara J. Wedel, Fergus Gerard Paul Earley, Frank J. Wessels, Ayako Hirao, Ulrich Ebbinghaus-Kintscher, Thomas C. Sparks, Danny Karmon
Publikováno v:
Pesticide Biochemistry and Physiology. 167:104587
Insecticide resistance has been and continues to be a significant problem for invertebrate pest control. As such, effective insecticide resistance management (IRM) is critical to maintain the efficacy of current and future insecticides. A technical g
Publikováno v:
Journal of Chemical Biology. 7:125-128
Neonicotinoid insecticides selectively target the invertebrate nicotinic acetylcholine receptor and disrupt excitatory cholinergic neurotransmission. First launched over 20 years ago, their broad pest spectrum, variety of application methods and rela
Autor:
Christoph Grimm, Christian Gnamm, Daniel P. Kloer, Ana Cristina Dutton, André Jeanguenat, Andrew J. Crossthwaite
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3800-3806
Novel insecticidal anthranilamides with elaborated sulfur-containing groups are described. The synthesis of compounds with functional groups such as sulfoximines and scarcely reported groups such as sulfonimidoyl hydrazides and hydroxylamides, their
Publikováno v:
Trends in Pharmacological Sciences. 27:426-431
There is increasing awareness of the compartmentalization of cAMP signalling – the means by which cAMP levels change in discrete domains of the cell with discrete local consequences. Current developments in understanding the organization of adenyly
Publikováno v:
Molecular Pharmacology. 69:608-617
Although protein scaffolding complexes compartmentalize protein kinase A (PKA) and phosphodiesterases to optimize cAMP signaling, adenylyl cyclases, the sources of cAMP, have been implicated in very few direct protein interactions. The N termini of a