Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Andrew J. Cohoon"'
Publikováno v:
Addictive Behaviors Reports, Vol 15, Iss , Pp 100401- (2022)
Background: Individuals with a family history of alcohol and other substance use disorders (FH+) are several times more likely to develop alcohol problems compared to individuals with no such family histories (FH–). Here we sought to evaluate assoc
Externí odkaz:
https://doaj.org/article/8fc52492765643898b54914ca37dd697
Autor:
William R Lovallo, Ashley Acheson, Andrew J Cohoon, Kristen H Sorocco, Andrea S Vincent, Colin A Hodgkinson, David Goldman
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218212 (2019)
Early life adversity (ELA) negatively affects health behaviors in adulthood, but pathways from ELA exposure to behavioral outcomes are poorly understood. ELA in childhood and adolescence may translate into adult outcomes by way of modified glucocorti
Externí odkaz:
https://doaj.org/article/8a9b4a52c3994ce6b3d72586c021b410
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205723 (2018)
Early life adversity (ELA) contributes to behavioral impulsivity along with risk for substance use disorders, both accompanied by blunted stress-axis reactivity. However, the biological contributors to blunted stress reactivity are not known. We took
Externí odkaz:
https://doaj.org/article/5327a281322e46f99c871e0a9a5f9e8d
Publikováno v:
Experimental and Clinical Psychopharmacology. 27:153-159
Increased discounting (devaluing) of delayed rewards is associated with nearly all types of substance use disorders (SUDs) and is also present in individuals with family histories of SUDs. Early life adversity (ELA) likely contributes to these findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7d5ee5267f2c521d0af05d86267977
https://doi.org/10.1037/pha0000241
https://doi.org/10.1037/pha0000241
Publikováno v:
Addiction
Background and aims People with blunted stress reactivity have poor impulse control and also show increased risk for alcoholism. Exposure to early life adversity (ELA) contributes to blunted reactivity, but individual differences in susceptibility to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd63f737633e7f87dbd296edb9773812
https://doi.org/10.1111/add.14501
https://doi.org/10.1111/add.14501
Autor:
Sukyung Woo, Deborah Wright, Won S. Yang, Andrew J. Cohoon, Randy L. Jensen, Eun Ha Kim, April M. Teague, Rheal A. Towner, Yan Zhao, Alexandra Ikeguchi, Sarah Sung, Satish Sharan, James Battiste
Publikováno v:
Neuro Oncol
BACKGROUND The nitrone compound OKN-007 is a novel anti-cancer agent. In glioblastoma xenografts, OKN-007 reduces cell proliferation and angiogenesis, and increases apoptosis. Here we report on the safety, efficacy, and pharmacokinetics (PK) of OKN-0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2818179f117523f3f42cd74ae7f92c
https://europepmc.org/articles/PMC7650506/
https://europepmc.org/articles/PMC7650506/
Publikováno v:
Addictive Behaviors. 77:247-254
Individuals with a family history of alcohol and other drug use disorders (FH+) are at increased risk for developing substance use disorders themselves relative to those with no such histories (FH-). Here we sought to identify key characteristics ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33ddfa3c755ec5358ec8a1370e476a1
https://doi.org/10.1016/j.addbeh.2017.10.014
https://doi.org/10.1016/j.addbeh.2017.10.014
Publikováno v:
Stress
Women have smaller cortisol responses to psychological stress than men do, and women taking hormonal contraceptives (HC+) have smaller responses than HC- women. Cortisol secretion undergoes substantial diurnal variation, with elevated levels in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758a31609f0bddde250c0fd58dfd4d1a
https://europepmc.org/articles/PMC6525075/
https://europepmc.org/articles/PMC6525075/
Autor:
Kristen H. Sorocco, Ashley Acheson, Andrea S. Vincent, Colin A. Hodgkinson, Andrew J. Cohoon, David Goldman, William R. Lovallo
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Risk for alcoholism may be enhanced by exposure to early life adversity (ELA) in persons with genetic vulnerabilities. We examined ELA in the presence of a common variant of the gene for the enzyme catechol-o-methyltransferase (COMT, Val1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9399c55a52bb516811339214ba8b6a63
https://pubmed.ncbi.nlm.nih.gov/31150143
https://pubmed.ncbi.nlm.nih.gov/31150143
Autor:
William R. Lovallo, Andrew J. Cohoon, Kristen H. Sorocco, Jordan R. Hoffmeister, Ashley Acheson
Publikováno v:
Drug Alcohol Depend
Background Some individuals are resistant to alcohol use disorders despite high levels of intake. Addiction Resistance (AR) measures the disparity between alcohol consumption and alcohol use disorder (AUD) symptoms, such that some persons exhibit few
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3423affb9f16b4fc1f6dea523c8c3fd
https://pubmed.ncbi.nlm.nih.gov/31539868
https://pubmed.ncbi.nlm.nih.gov/31539868