Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrew J. Bills"'
Autor:
John J. Kremer, C. Michael Foley, William A. Meier, Hepei Chen, Mark A. Osinski, Andrew J. Bills, Nathanael J. Hanke
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 75:27-37
Introduction Nonclinical safety studies are increasingly incorporating cardiac safety endpoints to discover potential cardiovascular liabilities. This trend for more thorough cardiovascular nonclinical safety evaluation is prudent given the high attr
Autor:
John J. Kremer, Hepei Chen, Andrew J. Bills, C. Michael Foley, Gary T. Wittwer, Andrea Z. Mitchell, Mark A. Osinski
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:62-73
Introduction Dogs are commonly used in cardiovascular drug safety assessment, and implanted telemetry models include subcutaneous or epicardial electrocardiogram (ECG) electrode placements. The purpose of this study was to determine the sensitivity o
Autor:
Michael Taschwer, Kenneth S. Latimer, Andrea Z. Mitchell, Jacqueline A. Walisser, Alok K. Sharma, Mark A. Osinski, Andrew J. Bills
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:52-61
Introduction Electrocardiogram (ECG) signals in safety pharmacology studies are generally collected via subcutaneous or epicardial leads. Subcutaneous placement is an easier procedure, but signals often contain artifacts. Epicardial leads offer impro
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e34
Autor:
John J. Kremer, Michael Taschwer, Anna M. Williams, Gary T. Wittwer, Andrea Z. Mitchell, Andrew J. Bills, Mark A. Osinski, C. Michael Foley
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e35