Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Andrew J. Bean"'
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279258 (2022)
Graduate admissions committees throughout the United States examine both quantitative and qualitative data from applicants to make admissions determinations. A number of recent studies have examined the ability of commonly used quantitative metrics s
Externí odkaz:
https://doaj.org/article/fb32279be384491d98c6e75bdbbc22dc
Autor:
Andrew J. Bean
The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Traffic
Autor:
Frederick F. Lang, Roel G. Verhaak, Raghu Kalluri, Edgar T. Walters, Juan Fueyo, George A. Calin, Andrew J. Bean, Hoon Kim, Joy Gumin, Anwar Hossain, Tal Shahar, Lynette M. Phillips, Javier Figueroa
GA-hMSC-derived exosomes increase GSC proliferation and clonogenicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e210eaa87f747e5ff2819b031d4e801
https://doi.org/10.1158/0008-5472.22419074.v1
https://doi.org/10.1158/0008-5472.22419074.v1
Autor:
Frederick F. Lang, Roel G. Verhaak, Raghu Kalluri, Edgar T. Walters, Juan Fueyo, George A. Calin, Andrew J. Bean, Hoon Kim, Joy Gumin, Anwar Hossain, Tal Shahar, Lynette M. Phillips, Javier Figueroa
MSC-derived exosomes contain highly expressed and highly enriched miRNA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d52e5cce55718faa6ab4102d839a771
https://doi.org/10.1158/0008-5472.22419056
https://doi.org/10.1158/0008-5472.22419056
Autor:
Frederick F. Lang, Roel G. Verhaak, Raghu Kalluri, Edgar T. Walters, Juan Fueyo, George A. Calin, Andrew J. Bean, Hoon Kim, Joy Gumin, Anwar Hossain, Tal Shahar, Lynette M. Phillips, Javier Figueroa
Tumor–stromal communications impact tumorigenesis in ways that are incompletely understood. Here, we show that glioma-associated human mesenchymal stem cells (GA-hMSC), a newly identified stromal component of glioblastoma, release exosomes that inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c83d9e5360aff02c2aba9fb2ea253ad4
https://doi.org/10.1158/0008-5472.c.6510284.v1
https://doi.org/10.1158/0008-5472.c.6510284.v1
Autor:
John W. McLean, Julie A. Wilson, Tina Tian, Jennifer A. Watson, Mary VanHart, Andrew J. Bean, Steven S. Scherer, David K. Crossman, Eroboghene Ubogu, Scott M. Wilson
Publikováno v:
J Neurosci
Endosomal sorting plays a fundamental role in directing neural development. By altering the temporal and spatial distribution of membrane receptors, endosomes regulate signaling pathways that control the differentiation and function of neural cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb129d750cf665d341f1b4bd2fdd090a
https://doi.org/10.1523/jneurosci.2481-21.2022
https://doi.org/10.1523/jneurosci.2481-21.2022
Autor:
Jennifer A Watson, Bula J Bhattacharyya, Jada H Vaden, Julie A Wilson, Mert Icyuz, Alan D Howard, Edward Phillips, Tara M DeSilva, Gene P Siegal, Andrew J Bean, Gwendalyn D King, Scott E Phillips, Richard J Miller, Scott M Wilson
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005290 (2015)
Neurons are particularly vulnerable to perturbations in endo-lysosomal transport, as several neurological disorders are caused by a primary deficit in this pathway. In this report, we used positional cloning to show that the spontaneously occurring n
Externí odkaz:
https://doaj.org/article/4fa74ad0928c45cbb6f41a27408027a2
Publikováno v:
Cancer Biol Ther
Neuroblastoma is the most common malignancy in infants. Overexpression of the epidermal growth factor receptor (EGFR) in neuroblastoma tumors underlies resistance to chemotherapeutics. UBE4B, an E3/E4 ubiquitin ligase involved in EGFR degradation, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a16c7f66c6eb1c8495f7b20f2157d48
https://doi.org/10.1080/15384047.2019.1647049
https://doi.org/10.1080/15384047.2019.1647049
Autor:
Kimiya Memarzadeh, Jeffrey A. Frost, Heather S. Carr, Courtney Olsen, Andrew J. Bean, Arzu Ulu
Publikováno v:
Endocrinology. 160:1031-1043
The G(i)-coupled somatostatin receptor 2 (SST(2)) is a G protein–coupled receptor (GPCR) that mediates many of somatostatin’s neuroendocrine actions. Upon stimulation, SST(2) is rapidly internalized and transported to early endosomes before being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2148c17fffa01d374b08732cd7be549
https://doi.org/10.1210/en.2018-00865
https://doi.org/10.1210/en.2018-00865
Mycobacterium tuberculosis type VII secreted effector EsxH targets host ESCRT to impair trafficking.
Autor:
Alka Mehra, Aleena Zahra, Victor Thompson, Natalie Sirisaengtaksin, Ashley Wells, Maura Porto, Stefan Köster, Kristen Penberthy, Yoshihisha Kubota, Amelie Dricot, Daniel Rogan, Marc Vidal, David E Hill, Andrew J Bean, Jennifer A Philips
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003734 (2013)
Mycobacterium tuberculosis (Mtb) disrupts anti-microbial pathways of macrophages, cells that normally kill bacteria. Over 40 years ago, D'Arcy Hart showed that Mtb avoids delivery to lysosomes, but the molecular mechanisms that allow Mtb to elude lys
Externí odkaz:
https://doaj.org/article/8cf2ec156ac647b2b5f8f2e3b35e59d3