Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Andrew J Wood"'
Autor:
Lewis Macdonald, Gillian C Taylor, Jennifer Margaret Brisbane, Ersi Christodoulou, Lucy Scott, Alex von Kriegsheim, Janet Rossant, Bin Gu, Andrew J Wood
Publikováno v:
eLife, Vol 11 (2022)
Auxin-inducible degrons are a chemical genetic tool for targeted protein degradation and are widely used to study protein function in cultured mammalian cells. Here, we develop CRISPR-engineered mouse lines that enable rapid and highly specific degra
Externí odkaz:
https://doaj.org/article/37d766044e734f3c97a2d073fbe2492a
Autor:
Andrew J Wood
Publikováno v:
Lateral, Vol 8, Iss 2 (2019)
Stevphen Shukaitis has produced an interesting text by situating a strategic conversation between artistic avant-gardes and autonomist political movements. He begins with a plea for rethinking strategy, and not just questions of tactics, in seeking r
Externí odkaz:
https://doaj.org/article/185914c5cfcd4958b7d309121a6bbaae
Autor:
Eirini M Kallimasioti-Pazi, Keerthi Thelakkad Chathoth, Gillian C Taylor, Alison Meynert, Tracy Ballinger, Martijn J E Kelder, Sébastien Lalevée, Ildem Sanli, Robert Feil, Andrew J Wood
Publikováno v:
PLoS Biology, Vol 16, Iss 12, p e2005595 (2018)
Genome editing occurs in the context of chromatin, which is heterogeneous in structure and function across the genome. Chromatin heterogeneity is thought to affect genome editing efficiency, but this has been challenging to quantify due to the presen
Externí odkaz:
https://doaj.org/article/5d84a8fbada2410c8fe18bed75f1ab24
Autor:
Madapura M Pradeepa, Fionnuala McKenna, Gillian C A Taylor, Hemant Bengani, Graeme R Grimes, Andrew J Wood, Shipra Bhatia, Wendy A Bickmore
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006677 (2017)
Long noncoding RNAs (lncRNAs) have been implicated in various biological functions including the regulation of gene expression, however, the functionality of lncRNAs is not clearly understood and conflicting conclusions have often been reached when c
Externí odkaz:
https://doaj.org/article/5f753eeb62ae4ecdb1c08f534831cf21
Autor:
Elan L. Guterman, Mary P. Mercer, Andrew J. Wood, Edilberto Amorim, Jonathan K. Kleen, Daniel Gerard, Colleen Kellison, Scott Yamashita, Benjamin Auerbach, Nikita Joshi, Karl A. Sporer
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Background Point‐of‐care electroencephalography (EEG) devices can be rapidly applied and do not require specialized technologists, creating new opportunities to use EEG during prehospital care. We evaluated the feasibility of point‐of
Externí odkaz:
https://doaj.org/article/878fb358e1df4da7884a79ee80300934
Publikováno v:
PLoS Genetics, Vol 3, Iss 2, p e20 (2007)
Imprinted genes undergo epigenetic modifications during gametogenesis, which lead to transcriptional silencing of either the maternally or the paternally derived allele in the subsequent generation. Previous work has suggested an association between
Externí odkaz:
https://doaj.org/article/9e4645a22f644ffaa18238795672ef9b
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/c9b71fc688ec4bbf8268e4fcbfd974be
Autor:
Andrew J Wood, Rebecca J Oakey
Publikováno v:
PLoS Genetics, Vol 2, Iss 11, p e147 (2006)
The epigenetic events that occur during the development of the mammalian embryo are essential for correct gene expression and cell-lineage determination. Imprinted genes are expressed from only one parental allele due to differential epigenetic marks
Externí odkaz:
https://doaj.org/article/4c9f9401995f454c955383b699c5c7dd
Publikováno v:
Communications in Soil Science and Plant Analysis. 53:1672-1684
Autor:
Gillian C Taylor, Lewis Macdonald, Jennifer Margaret Brisbane, Ersi Christodoulou, Lucy Scott, Alex von Kriegsheim, Janet Rossant, Bin Gu, Andrew J Wood
Publikováno v:
MacDonald, L, Taylor, G, Brisbane, J, Christodoulou, E, Scott, L, von Kriegsheim, A, Rossant, J, Gu, B & Wood, A J 2022, ' Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons ', eLIFE, vol. 11 . https://doi.org/10.7554/eLife.77987
Auxin-inducible degrons are a chemical genetic tool for targeted protein degradation and are widely used to study protein function in cultured mammalian cells. Here, we develop CRISPR-engineered mouse lines that enable rapid and highly specific degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd043f0d620aca83bc9390be51da816d
https://www.pure.ed.ac.uk/ws/files/285851556/elife_77987_v2.pdf
https://www.pure.ed.ac.uk/ws/files/285851556/elife_77987_v2.pdf