Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Andrew J Urquhart"'
Autor:
Diána Hudecz, Sara Björk Sigurdardóttir, Sarah Christine Christensen, Casper Hempel, Andrew J Urquhart, Thomas Lars Andresen, Morten S Nielsen
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
The blood-brain barrier (BBB) is one of the main obstacles for therapies targeting brain diseases. Most macromolecules fail to pass the tight BBB, formed by brain endothelial cells interlinked by tight junctions. A wide range of small, lipid-soluble
Externí odkaz:
https://doaj.org/article/922698fa4c0a47eb9b69cb886bed49d9
Autor:
Franco Aparecido Rossato, Eun Young Choi, Andrew J. Urquhart, David A. Scott, Yin Shan E. Ng, Gopalan Gnanaguru, Ashley Mackey, Anthoula Arta, Patricia A. D'Amore, Thomas W. Gero
Publikováno v:
Free Radic Biol Med
Late-stage dry age-related macular degeneration (AMD) or geographic atrophy (GA) is an irreversible blinding condition characterized by degeneration of retinal pigment epithelium (RPE) and the associated photoreceptors. Clinical and genetic evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691e14ee0f6eb5eaca0221237af4d0e9
https://doi.org/10.1016/j.freeradbiomed.2021.11.026
https://doi.org/10.1016/j.freeradbiomed.2021.11.026
Publikováno v:
Molecules, Vol 24, Iss 11, p 2174 (2019)
Caprolactam, a precursor to nylon-6 has been investigated as part of our studies into the polymerization of materials at high pressure. Single-crystal X-ray and neutron powder diffraction data have been used to explore the high-pressure phase behavio
Externí odkaz:
https://doaj.org/article/f4cac6b147a84a84b2ef9dc6b0f4f167
Autor:
Heidi K. Noddeland, Pernille Kemp, Andrew J. Urquhart, Andreas Herchenhan, Klaus A. Rytved, Karsten Petersson, Louise B. Jensen
Publikováno v:
Noddeland, H K, Kemp, P, Urquhart, A J, Herchenhan, A, Rytved, K A, Petersson, K & Jensen, L B 2022, ' Reactive Oxygen Species-Responsive Polymer Nanoparticles to Improve the Treatment of Inflammatory Skin Diseases ', ACS Omega, vol. 7, no. 29, pp. 25055-25065 . https://doi.org/10.1021/acsomega.2c01071
Noddeland, H K, Kemp, P, Urquhart, A J, Herchenhan, A, Rytved, K A, Petersson, K & B. Jensen, L 2022, ' Reactive Oxygen Species-Responsive Polymer Nanoparticles to Improve the Treatment of Inflammatory Skin Diseases ', ACS Omega, vol. 7, no. 29, pp. 25055-25065 . https://doi.org/10.1021/acsomega.2c01071
Noddeland, H K, Kemp, P, Urquhart, A J, Herchenhan, A, Rytved, K A, Petersson, K & B. Jensen, L 2022, ' Reactive Oxygen Species-Responsive Polymer Nanoparticles to Improve the Treatment of Inflammatory Skin Diseases ', ACS Omega, vol. 7, no. 29, pp. 25055-25065 . https://doi.org/10.1021/acsomega.2c01071
To improve the quality of life for people living with chronic inflammatory skin diseases, we propose a new treatment strategy by exploring a stimuli-responsive drug delivery system. Formulations designed by exploiting smart materials can be programme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecddcef2c1ac57f1d1faed6c63187699
https://orbit.dtu.dk/en/publications/2018b4b7-354f-4b93-956f-94d56d9c4a20
https://orbit.dtu.dk/en/publications/2018b4b7-354f-4b93-956f-94d56d9c4a20
Publikováno v:
Drug Discovery Today. 24:1660-1668
Diseases of the retina cause vision loss and blindness, which have a profound impact on an individual's quality of life. The number of therapies available to treat retinal diseases is limited. Nanoparticle (NP)-based medicines represent one strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab08ed77c099ef3ecda2cb7c0bbd626
https://doi.org/10.1016/j.drudis.2019.04.004
https://doi.org/10.1016/j.drudis.2019.04.004
Autor:
Andrew J. Urquhart, Sara Björk Sigurdardóttir, Sarah Christine Christensen, Thomas Lars Andresen, Morten Nielsen, Diána Hudecz, Casper Hempel
Publikováno v:
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, no. 4, e0249686 . https://doi.org/10.1371/journal.pone.0249686
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, e0249686 . https://doi.org/10.1371/journal.pone.0249686
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, e0249686 . https://doi.org/10.1371/journal.pone.0249686
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
The blood-brain barrier (BBB) is one of the main obstacles for therapies targeting brain diseases. Most macromolecules fail to pass the tight BBB, formed by brain endothelial cells interlinked by tight junctions. A wide range of small, lipid-soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa30e19fe0204ed8693055ee68d52673
https://pure.au.dk/portal/da/publications/two-peptides-targeting-endothelial-receptors-are-internalized-into-murine-brain-endothelial-cells(c5af39a7-7a79-4414-9886-948bc7fdee5c).html
https://pure.au.dk/portal/da/publications/two-peptides-targeting-endothelial-receptors-are-internalized-into-murine-brain-endothelial-cells(c5af39a7-7a79-4414-9886-948bc7fdee5c).html
Autor:
Viktoria Sereti, Kasper Bendix Johnsen, Thomas Lars Andresen, Andrew J. Urquhart, Marieke Olsman, Melina Mühlenpfordt, Catharina de Lange Davies
Publikováno v:
Olsman, M, Sereti, V, Mühlenpfordt, M, Johnsen, K B, Andresen, T L, Urquhart, A J & Davies, C D L 2021, ' Focused Ultrasound and Microbubble Treatment Increases Delivery of Transferrin Receptor-Targeting Liposomes to the Brain ', Ultrasound in Medicine and Biology, vol. 47, no. 5, pp. 1343-1355 . https://doi.org/10.1016/j.ultrasmedbio.2021.01.014
Ultrasound in Medicine and Biology
Ultrasound in Medicine and Biology
The blood-brain barrier (BBB) is a major obstacle to treating several brain disorders. Focused ultrasound (FUS) in combination with intravascular microbubbles increases BBB permeability by opening tight junctions, creating endothelial cell openings,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb1e18deac8221f115c077e478d810e
https://orbit.dtu.dk/en/publications/c6745fc4-1d12-49c5-9fda-060e566fcf61
https://orbit.dtu.dk/en/publications/c6745fc4-1d12-49c5-9fda-060e566fcf61
Autor:
Anthoula Arta, Michael Larsen, Paul J. Kempen, Thomas Lars Andresen, Anne Zebitz Eriksen, Jannik B. Larsen, Andrew J. Urquhart
Publikováno v:
International journal of pharmaceutics. 588
Targeting nanocarrier drug delivery systems, that deliver drug payloads to the site of disease action, are frequently viewed as the future of nanocarrier based therapies but have struggled to breakthrough to the clinic in comparison to non-targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a62191d7c16c99072ee9bbb6aa357c
https://pubmed.ncbi.nlm.nih.gov/32750439
https://pubmed.ncbi.nlm.nih.gov/32750439
Autor:
Catharina de Lange Davies, Viktoria Sereti, Kristine Andreassen, Rasmus Eliasen, Sofie Snipstad, Marieke Olsman, Annemieke van Wamel, Sigrid Berg, Thomas Lars Andresen, Andrew J. Urquhart
Publikováno v:
Journal of Controlled Release
Olsman, M, Sereti, V, Andreassen, K, Snipstad, S, van Wamel, A, Eliasen, R, Berg, S, Urquhart, A J, Andresen, T L & Davies, C D L 2020, ' Ultrasound-mediated delivery enhances therapeutic efficacy of MMP sensitive liposomes ', Journal of controlled release, vol. 325, pp. 121-134 . https://doi.org/10.1016/j.jconrel.2020.06.024
Olsman, M, Sereti, V, Andreassen, K, Snipstad, S, van Wamel, A, Eliasen, R, Berg, S, Urquhart, A J, Andresen, T L & Davies, C D L 2020, ' Ultrasound-mediated delivery enhances therapeutic efficacy of MMP sensitive liposomes ', Journal of controlled release, vol. 325, pp. 121-134 . https://doi.org/10.1016/j.jconrel.2020.06.024
To improve therapeutic efficacy of nanocarrier drug delivery systems, it is essential to improve their uptake and penetration in tumour tissue, enhance cellular uptake and ensure efficient drug release at the tumour site. Here we introduce a tumour t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1d0fcb1f457386c3563464bf0ac529
https://hdl.handle.net/11250/2673754
https://hdl.handle.net/11250/2673754
Autor:
Sofie Snipstad, Annemieke van Wamel, Sigrid Berg, Rasmus Eliasen, Kristine Andreassen, Andrew J. Urquhart, Marieke Olsman, Thomas Lars Andresen, Catharina de Lange Davies, Viktoria Sereti
Publikováno v:
Journal of Controlled Release. 337:628
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c2e1fd4103d89e7605aa6348c8f02f1
https://doi.org/10.1016/j.jconrel.2021.08.005
https://doi.org/10.1016/j.jconrel.2021.08.005