Výsledky vyhledávání - "Andrew J Paris"

Akademický článek

Using selective lung injury to improve murine models of spatially heterogeneous lung diseases.

Autor: Andrew J Paris, Lei Guo, Ning Dai, Jeremy B Katzen, Priyal N Patel, G Scott Worthen, Jacob S Brenner

Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0202456 (2019)

Many lung diseases, such as the acute respiratory distress syndrome (ARDS), display significant regional heterogeneity with patches of severely injured tissue adjacent to apparently healthy tissue. Current mouse models that aim to mimic ARDS generall

Externí odkaz: https://doaj.org/article/a83cdd6ed33545c7a4c72087cccc4c55

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Neutrophils promote clearance of nuclear debris following acid-induced lung injury

Autor: G. Scott Worthen, Ning Dai, Andrew J. Paris, Lynn A. Spruce, Steven H. Seeholzer, Joseph H. Oved, Ping Wang, Mortimer Poncz, Kandace Gollomp, Kathryn M Rubey

Publikováno v: Blood. 137:392-397

Neutrophils are critical mediators of host defense in pathogen-induced and sterile inflammation. Excessive neutrophil activation has been associated with increased host pathology through collateral organ damage. The beneficial aspects of neutrophil a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8e81de06fe0d72761a5463dc5b190d
https://doi.org/10.1182/blood.2020005505

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Mesenchyme-free expansion and transplantation of adult alveolar progenitor cells: steps toward cell-based regenerative therapies

Autor: Elizabeth Q. Littauer, Derek C. Liberti, Edward E. Morrisey, Andrew E. Vaughan, Gan Zhao, Aaron I. Weiner, Kwaku K. Quansah, G. Scott Worthen, Andrew J. Paris, Katherine M. Neupauer, Sergio R. Jackson, Joseph N. Farshchian

Publikováno v: npj Regenerative Medicine, Vol 4, Iss 1, Pp 1-10 (2019)
NPJ Regenerative Medicine

Alveolar type-2 (AT2) cells are necessary for the lung’s regenerative response to epithelial insults such as influenza. However, current methods to expand these cells rely on mesenchymal co-culture, complicating the possibility of transplantation f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68848466eeda7f5b53efddb5a4791ec3
http://link.springer.com/article/10.1038/s41536-019-0080-9

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An inflammatory pulmonary insult post-traumatic brain injury worsens subsequent spatial learning and neurological outcomes

Autor: C. William Schwab, Daniel N. Holena, Jordan McCarry, Melpo Christofidou-Solomidou, Jose L. Pascual, Syed Ahmed, Douglas H. Smith, Andrew J. Paris, Ryan Leone, Lewis J. Kaplan, Yujin Suto, Christina L. Jacovides

Publikováno v: Journal of Trauma and Acute Care Surgery. 87:552-558

BACKGROUND Severe traumatic brain injury (TBI) patients are at high risk for early aspiration and pneumonia. How pneumonia impacts neurological recovery after TBI is not well characterized. We hypothesized that, independent of the cerebral injury, pn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb83900d17d30547ff6d0b724bcce02
https://doi.org/10.1097/ta.0000000000002403

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Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

Autor: Laurence C. Eisenlohr, Jeremy Katzen, Maria C. Basil, Chaitali Bhadiadra, Jeffrey H. Lin, Sushila A. Toulmin, G. Scott Worthen, Edward E. Morrisey, Andrew J. Paris

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Type II alveolar cells (AT2s) are critical for basic respiratory homeostasis and tissue repair after lung injury. Prior studies indicate that AT2s also express major histocompatibility complex class II (MHCII) molecules, but how MHCII expression by A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bed7e6b5f550671c2361f318d0b7973
http://europepmc.org/articles/PMC8239023

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Type II alveolar cells with constitutive expression of MHCII and limited antigen presentation capacity contribute to improved respiratory viral disease outcomes

Autor: Edward E. Morrisey, Sushila A. Toulmin, Laurence C. Eisenlohr, Jeremy Katzen, George S Worthen, Maria C. Basil, Bhadiadra C, Jerome Lin, Andrew J. Paris

Type II alveolar cells (AT2s) are critical for basic respiratory homeostasis and tissue repair after lung injury. Prior studies indicate that AT2s also express major histocompatibility complex II (MHCII) molecules, but how MHCII expression by AT2s is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d54b5c8bd6701545036652724e5d2b2
https://doi.org/10.1101/2021.03.18.435984

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