Zobrazeno 1 - 10
of 602
pro vyhledávání: '"Andrew J Murphy"'
Autor:
Katharine A Kott, Adam S Chan, Stephen T Vernon, Thomas Hansen, Taiyun Kim, Macha deDreu, Bavani Gunasegaran, Andrew J Murphy, Ellis Patrick, Peter J Psaltis, Stuart M Grieve, Jean Y Yang, Barbara Fazekas de St Groth, Helen M McGuire, Gemma A Figtree
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract Objective The importance of inflammation in atherosclerosis is well accepted, but the role of the adaptive immune system is not yet fully understood. To further explore this, we assessed the circulating immune cell profile of patients with c
Externí odkaz:
https://doaj.org/article/c6896394e4c5467bb8255df0f5093c80
Autor:
Dragana Dragoljevic, Man Kit Sam Lee, Gerard Pernes, Pooranee K Morgan, Cynthia Louis, Waled Shihata, Kevin Huynh, Arina A Kochetkova, Patrick W Bell, Natalie A Mellett, Peter J Meikle, Graeme I Lancaster, Michael J Kraakman, Prabhakara R Nagareddy, Beatriz Y Hanaoka, Ian P Wicks, Andrew J Murphy
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 4, Pp n/a-n/a (2023)
Abstract Objectives The leading cause of mortality in patients with rheumatoid arthritis is atherosclerotic cardiovascular disease (CVD). We have shown that murine arthritis impairs atherosclerotic lesion regression, because of cellular cholesterol e
Externí odkaz:
https://doaj.org/article/48c0e47238314555b62510482001ecff
Autor:
Jean-Francois Gautier, Nicolas Venteclef, Assam El-Osta, Andrew J Murphy, Darren M Riddy, Helene L Kammoun, Sanja Bosnyak-Gladovic, Rocio De la Fuente Gonzalez, Jon Merlin, Mark Ziemann, Stewart Fabb, Tracie L Pierce, Natalie Diepenhorst, Patricia Rueda, William N Charman, Arthur Christopoulos, Patrick M Sexton, Roger J Summers, Mark A Febbraio, Philippe Delerive, Christopher J Langmead
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 2 (2021)
Externí odkaz:
https://doaj.org/article/4720f931b7654da0bb23e3c27d888fd0
Autor:
Robert Rangeley, Bárbara de Moura Neves, Neus Campanyà-Llovet, Mary Denniston, Rodd Laing, Katrina Anthony, Paul McCarney, Reba McIver, Jennifer Whyte, Alexandra R Vance, Isabelle Jubinville, Jean Hodgson, Andrew J Murphy, David Cote
Publikováno v:
Ecology and Society, Vol 27, Iss 4, p 47 (2022)
Labrador Inuit have expressed concern about the impacts of climate change on their health and well-being and their future access to marine resources, including fisheries. This study filled important knowledge gaps identified by the Nunatsiavut Govern
Externí odkaz:
https://doaj.org/article/0dfb387ebf544eea810da3f02ab1d79a
Autor:
Senem Aykul, Richard A Corpina, Erich J Goebel, Camille J Cunanan, Alexandra Dimitriou, Hyon Jong Kim, Qian Zhang, Ashique Rafique, Raymond Leidich, Xin Wang, Joyce McClain, Johanna Jimenez, Kalyan C Nannuru, Nyanza J Rothman, John B Lees-Shepard, Erik Martinez-Hackert, Andrew J Murphy, Thomas B Thompson, Aris N Economides, Vincent Idone
Publikováno v:
eLife, Vol 9 (2020)
Activin A functions in BMP signaling in two ways: it either engages ACVR1B to activate Smad2/3 signaling or binds ACVR1 to form a non-signaling complex (NSC). Although the former property has been studied extensively, the roles of the NSC remain unex
Externí odkaz:
https://doaj.org/article/f046d1441e0d4e23a1f1b1baf6223516
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Abstract Macrophages are the first immune cells in the developing embryo and have a central role in organ development, homeostasis, immunity and repair. Over the last century, our understanding of these cells has evolved from being thought of as simp
Externí odkaz:
https://doaj.org/article/74f9aa12b7d44458a681fac9c613a3e2
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract The importance of metabolic regulation in the immune system has launched back into the limelight in recent years. Various metabolic pathways have been examined in the context of their contribution to maintaining immune cell homeostasis and f
Externí odkaz:
https://doaj.org/article/cf5a4729a1a44c3c873361e473fecd1a
Autor:
Kang-Yu Peng, Christopher K Barlow, Helene Kammoun, Natalie A Mellett, Jacquelyn M Weir, Andrew J Murphy, Mark A Febbraio, Peter J Meikle
Publikováno v:
Metabolites, Vol 11, Iss 3, p 188 (2021)
There is a strong association between hepatocyte phospholipid homeostasis and non-alcoholic fatty liver disease (NAFLD). The phosphatidylcholine to phosphatidylethanolamine ratio (PC/PE) often draws special attention as genetic and dietary disruption
Externí odkaz:
https://doaj.org/article/5ce77a6cc4864340ad96bdf2249349c3
Autor:
Jesse J R Masson, Andrew J Murphy, Man K S Lee, Matias Ostrowski, Suzanne M Crowe, Clovis S Palmer
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183931 (2017)
Metabolism plays a fundamental role in supporting the growth, proliferation and effector functions of T cells. We investigated the impact of HIV infection on key processes that regulate glucose uptake and mitochondrial biogenesis in subpopulations of
Externí odkaz:
https://doaj.org/article/442c69c097fe4db091d8035613d003c6
Autor:
Keiko Takahashi, Rachel Kim, Colette Lauhan, Yuna Park, Nghiep G Nguyen, Dietmar Vestweber, Melissa G Dominguez, David M Valenzuela, Andrew J Murphy, George D Yancopoulos, Nicholas W Gale, Takamune Takahashi
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177192 (2017)
Renal vascular development is a coordinated process that requires ordered endothelial cell proliferation, migration, intercellular adhesion, and morphogenesis. In recent decades, studies have defined the pivotal role of endothelial receptor tyrosine
Externí odkaz:
https://doaj.org/article/a048c4993700443b8ff05d3a4013a0ff