Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Andrew J Lautz"'
Autor:
Mihir R. Atreya, Shayantan Banerjee, Andrew J. Lautz, Matthew N. Alder, Brian M. Varisco, Hector R. Wong, Jennifer A. Muszynski, Mark W. Hall, L. Nelson Sanchez-Pinto, Rishikesan Kamaleswaran, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Scott L. Weiss, Michael T. Bigham, Parag N. Jain, Adam J. Schwarz, Riad Lutfi, Jeffrey Nowak, Geoffrey L. Allen, Neal J. Thomas, Jocelyn R. Grunwell, Torrey Baines, Michael Quasney, Bereketeab Haileselassie, Chris J. Lindsell
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104938- (2024)
Summary: Background: Multiple organ dysfunction syndrome (MODS) disproportionately drives morbidity and mortality among critically ill patients. However, we lack a comprehensive understanding of its pathobiology. Identification of genes associated wi
Externí odkaz:
https://doaj.org/article/162e22e81e7c4a51b9298a80581e6c4c
Autor:
Kumaran Senthil, Ryan W. Morgan, Marco M. Hefti, Michael Karlsson, Andrew J. Lautz, Constantine D. Mavroudis, Tiffany Ko, Vinay M. Nadkarni, Johannes Ehinger, Robert A. Berg, Robert M. Sutton, Francis X. McGowan, Todd J. Kilbaugh
Publikováno v:
Resuscitation Plus, Vol 6, Iss , Pp 100124- (2021)
Objective: Cerebral mitochondrial dysfunction is a key mediator of neurologic injury following cardiac arrest (CA) and is regulated by the balance of fusion and fission (mitochondrial dynamics). Under stress, fission can decrease mitochondrial mass a
Externí odkaz:
https://doaj.org/article/19c14c14f8fc4485b3225576a21474de
Publikováno v:
Pediatr Crit Care Med
OBJECTIVES Sepsis-associated myocardial dysfunction is common in pediatric septic shock and negatively impacts outcomes. Early estimation of sepsis-associated myocardial dysfunction risk has the potential to inform clinical care and improve clinical
Autor:
Mihir R. Atreya, Shayantan Banerjee, Andrew J. Lautz, Matthew N. Alder, Brian M. Varisco, hector wong, Jennifer A. Muszynski, Mark W. Hall, L. Nelson Sanchez-Pinto, Rishikesan Kamaleswaran
Background Multiple organ dysfunction syndrome (MODS) disproportionately drives sepsis morbidity and mortality among children. The biology of this heterogeneous syndrome is complex, dynamic, and incompletely understood. Gene expression signatures cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd7dea00cdd516f877e1666e3007d16b
https://doi.org/10.21203/rs.3.rs-2093663/v1
https://doi.org/10.21203/rs.3.rs-2093663/v1
Autor:
Andrew J. Lautz, Basilia Zingarelli
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3523 (2019)
Myocardial dysfunction is common in septic shock and post-cardiac arrest but manifests differently in pediatric and adult patients. By conventional echocardiographic parameters, biventricular systolic dysfunction is more prevalent in children with se
Externí odkaz:
https://doaj.org/article/16aed3e666a24586ae0370bcd70dad01
High-quality cardiopulmonary resuscitation (CPR) with targeted post-arrest management have resulted in dramatic improvements in survival with favourable neurological outcome from in-hospital paediatric cardiac arrest over the past two decades. High-q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a2d8c3b5edd6b308aec5fd737198b2
https://doi.org/10.1093/med/9780198794592.003.0004
https://doi.org/10.1093/med/9780198794592.003.0004
Autor:
Mary Frey, Adam A. Vukovic, Matthew Zackoff, Gary L. Geis, Andrew J Lautz, Erika Stalets, Benjamin T. Kerrey, Tena Pham, Andrea Maxwell, Erin F Hoehn, Mary K Cabrera-Thurman, Preston Dean
Publikováno v:
Pediatric Quality & Safety
Introduction: Patients with physiologic disorders, such as hypoxemia or hypotension, are at high risk of peri-intubation cardiac arrest. Standardization improves emergency tracheal intubation safety, but no published reports describe initiatives to r
Publikováno v:
Critical Care Explorations
Supplemental Digital Content is available in the text.
Objectives: Circulatory dysfunction has been associated with mortality in children with septic shock. However, the mortality risk attributable to myocardial dysfunction per se has not been e
Objectives: Circulatory dysfunction has been associated with mortality in children with septic shock. However, the mortality risk attributable to myocardial dysfunction per se has not been e
Autor:
Ryan W. Morgan, Andrew J Lautz, Constantine D. Mavroudis, Nancy Craig, Sejin Jeong, Robert A. Berg, Robert M. Sutton, Todd J. Kilbaugh, Michael Karlsson, William P. Landis, Vinay M. Nadkarni, Yuxi Lin
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 197:905-912
Many in-hospital cardiac arrests are precipitated by hypotension, often associated with systemic inflammation. These patients are less likely to be successfully resuscitated, and novel approaches to their treatment are needed.To determine if the addi
Autor:
Daniel J. Licht, Robert A. Berg, Vinay M. Nadkarni, Michael Karlsson, Robert M. Sutton, Ryan W. Morgan, Constantine D. Mavroudis, Andrew J Lautz, Todd J. Kilbaugh, Tiffany Ko
Publikováno v:
Critical care medicine. 47(3)
OBJECTIVES Less than half of the thousands of children who suffer in-hospital cardiac arrests annually survive, and neurologic injury is common among survivors. Hemodynamic-directed cardiopulmonary resuscitation improves short-term survival, but its